肉牛生产系统的盈利能力在很大程度上取决于繁殖特性。不幸的是,某些特征,如第一次产牛年龄(AFC),产卵间隔(CI),和妊娠长度(GL),由于传统育种计划的低遗传力(0.01-0.12)和性别有限的特征,可能对传统育种计划构成挑战。另一个重要方面是保护适应哥伦比亚地区的动物的遗传资源,这意味着在国家市场上保存和合理使用克里奥尔品种。因此,这项研究旨在确定影响雌性繁殖性状的克里奥尔牛品种BlancoOrejinegro(BON)的基因组区域。该数据集包括439只动物和118,116个单核苷酸多态性(SNP)标记。GS3程序用于使用BAYESCπ方法鉴定SNP效应。对AFC有效的SNP的数量为25,CI为1527,GL为23。发现的一些基因与生殖和生长性状以及免疫反应和环境适应ECE1,EPH,EPHB2,SMARCAL1,IGFBP5,IGFBP2,FCGRT,EGFR,MUL1,PINK1,STPG1,CNGB1,TGFB1,OXTR,IL22RA1,MYOM3,OXTR,CNR2,HIVEP3,CTPS1,CXCL8,FCGRT,MREG,TMEM169,PECR,MC1R。我们的结果表明,哥伦比亚克里奥尔牛品种BlancoOrejinegro的遗传结构做出了很高的贡献,这可能会影响应包括在实施遗传改良和保护计划中。
The profitability of the beef cattle production system relies heavily on reproductive traits. Unfortunately, certain traits, such as age at first calving (AFC), calving interval (CI), and gestation length (GL), can pose challenges in traditional breeding programs because of their low heritability (0.01-0.12) and sex-limited characteristics. Another important aspect is the conservation of the genetic resources of animals adapted to the Colombian regions, which implies the preservation and rational use of the creole breeds in the country market. Therefore, this
study aimed to identify genomic regions in the creole cattle breed Blanco Orejinegro (BON) that influence the reproductive traits in females. The dataset comprised 439 animals and 118,116 single-nucleotide polymorphisms\' (SNPs) markers. The GS3 program was used to identify the SNP effects employing the BAYES Cπ methodology. The number of SNPs with effect for AFC was 25, 1527 for CI, and 23 for GL. Some of the genes found associated with reproductive and growth traits as well as immune response and environmental adaptation ECE1, EPH, EPHB2, SMARCAL1, IGFBP5, IGFBP2, FCGRT, EGFR, MUL1, PINK1, STPG1, CNGB1, TGFB1, OXTR, IL22RA1, MYOM3, OXTR, CNR2, HIVEP3, CTPS1, CXCL8, FCGRT, MREG, TMEM169, PECR, and MC1R. Our results evidenced a high contribution of the genetic architecture of the Colombian creole cattle breed Blanco Orejinegro that may impact should be included in implementing genetic improvement and conservation programs.