背景:许多国家的预防性抗凝药物,包括南非,规定不足。这导致了不可接受的发病率和死亡率。
方法:南部非洲血栓和止血协会召开会议,更新以前的指南,并审查包括其他协会指南在内的新文献。委员会中有以下专业的代表:麻醉药,心脏病学,临床血液学,重症监护,妇产科,血液病理学,内科,神经学,骨科手术和肺科。会上提交了一份文件草案,然后通过协商一致协议进行了修订。为了避免局部偏差,该准则由公认的国际外部专家裁定。
结论:简洁,针对南非的疾病,为内科和外科患者的血栓预防和治疗制定了实用的最新指南.希望该指南将继续改善该国的抗凝实践,我们认为这将直接有利于患者的治疗结果。
BACKGROUND: Pharmacological prophylactic anticoagulation in many countries, including South Africa, is under-prescribed. This has resulted in unacceptable rates of morbidity and mortality.
METHODS: The Southern African Society of Thrombosis and Haemostasis held a meeting to update the previous
guideline and review new literature including
guidelines from other societies. The following specialties were represented on the committees: anaesthetics, cardiology, clinical haematology, critical care, obstetrics and gynaecology, haematopathology, internal medicine, neurology, orthopaedic surgery and pulmonology. A draft document was presented at the meeting, which was then revised by
consensus agreement. To avoid local bias, the
guideline was adjudicated by recognised international external experts.
CONCLUSIONS: A concise, practical updated
guideline for thromboprophylaxis and treatment in medical and surgical patients has been produced for South African conditions. It is hoped that this guideline will continue to improve anticoagulation practice in this country, which we believe will directly benefit patient outcomes.