anaesthesia

麻醉
  • 文章类型: Journal Article
    动脉压监测和管理是手术患者血液动力学治疗的主要手段。本文介绍了在伦敦举行的第11届POQI围手术期质量倡议(POQI)共识会议期间制定的关于围手术期动脉压管理的最新共识声明和建议。英国,2023年6月4日至6日,其中包括一组不同的国际专家。基于改进的德尔菲法,我们建议高危患者术中平均动脉压≥60mmHg.我们进一步建议在静脉或室压升高时增加平均动脉压目标,并根据推测的潜在原因治疗低血压。当治疗术中高血压时,我们建议这样做小心,以避免低血压。临床医生应考虑连续术中动脉压监测,因为与间歇性动脉压监测相比,它可以帮助减少低血压的严重程度和持续时间。术后低血压通常未被识别,并且可能比术中低血压更重要,因为它通常被延长且未经治疗。未来的研究应集中于确定患者特异性和器官特异性低血压的伤害阈值以及术中低血压的最佳治疗策略,包括血管加压药的选择。还需要进行研究,以指导监测和管理策略,以识别,预防,治疗术后低血压。
    Arterial pressure monitoring and management are mainstays of haemodynamic therapy in patients having surgery. This article presents updated consensus statements and recommendations on perioperative arterial pressure management developed during the 11th POQI PeriOperative Quality Initiative (POQI) consensus conference held in London, UK, on June 4-6, 2023, which included a diverse group of international experts. Based on a modified Delphi approach, we recommend keeping intraoperative mean arterial pressure ≥60 mm Hg in at-risk patients. We further recommend increasing mean arterial pressure targets when venous or compartment pressures are elevated and treating hypotension based on presumed underlying causes. When intraoperative hypertension is treated, we recommend doing so carefully to avoid hypotension. Clinicians should consider continuous intraoperative arterial pressure monitoring as it can help reduce the severity and duration of hypotension compared to intermittent arterial pressure monitoring. Postoperative hypotension is often unrecognised and might be more important than intraoperative hypotension because it is often prolonged and untreated. Future research should focus on identifying patient-specific and organ-specific hypotension harm thresholds and optimal treatment strategies for intraoperative hypotension including choice of vasopressors. Research is also needed to guide monitoring and management strategies for recognising, preventing, and treating postoperative hypotension.
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  • 文章类型: Journal Article
    背景:临床医生和研究人员通过社交媒体(SoMe)传播医疗实践和科学信息正在增加。广泛的信息暴露可以促进科学界内部的联系,克服获取来源的障碍,增加辩论,并揭示外行人的观点和偏好。另一方面,缺乏科学证据的做法也可能得到推广,外行人可能会误解专业信息,临床医生可能会受到职业地位的侵蚀。该项目的目的是提高认识,并向麻醉界和广大临床医生提供有关潜在风险的建议,倡导负责任地使用SoMe来传播与医疗实践和知识有关的信息。
    方法:在多学科专家小组中进行了具有预定共识标准的改良Delphi过程,包括麻醉师-重症医师,临床心理学家,和法医学专家。确定了六个项目:伦理学和道义学原则,通过社交媒体分享信息的做法,法律方面,心理方面,自我推销,和适当传播的标准。陈述和理由被制作出来,并受到小组成员的盲目投票。达成共识后,编写了一份文件,然后由不参与共识进程的专家进行外部审查。该项目由意大利麻醉镇痛复苏和重症监护协会(SIAARTI)推广。
    结果:产生了12份声明,所有人都达成了共识。小组的结论是,指导通过SoMe传播专业信息的一般原则必须与道德的一般原则保持一致,道义,和科学有效性,指导医学专业和一般科学。在通过SoMe进行沟通时,必须保持专业公平。不应传播缺乏科学证据支持的医疗实践。在传播信息之前必须获得患者的知情同意,images,或数据。自我推销不能优先于任何这些原则。
    结论:在分享关于SoMe的医疗实践和科学信息时,建议医疗保健专业人员认真和道德地行事。应遵守地方性法规。关于SoMe为此目的的潜在风险和适当性的机构培训可能有助于维护专业诚信。
    BACKGROUND: Dissemination of medical practice and scientific information through social media (SoMe) by clinicians and researchers is increasing. Broad exposure of information can promote connectivity within the scientific community, overcome barriers to access to sources, increase debate, and reveal layperson perspectives and preferences. On the other hand, practices lacking scientific evidence may also be promoted, laypeople may misunderstand the professional message, and clinician may suffer erosion of professional status. The aim of this project was to enhance awareness and advise the anesthesia community and clinicians at large about the potential risks advocate for responsible use of SoMe to disseminate information related to medical practices and knowledge.
    METHODS: A modified Delphi process with prespecified consensus criteria was conducted among a multidisciplinary panel of experts, including anesthesiologists-intensivists, clinical psychologists, and forensic medicine specialists. Six items were identified: Ethics and deontological principles, the practice of sharing information via social media, legal aspects, psychological aspects, self-promotion, and criteria for appropriate dissemination. Statements and rationales were produced and subjected to blinded panelists\' votes. After reaching consensus, a document was written which then underwent external review by experts uninvolved in the consensus process. The project was promoted by the Italian Society of Anesthesia Analgesia Resuscitation and Intensive Care (SIAARTI).
    RESULTS: Twelve statements were produced, and consensus was achieved for all. The panel concluded that the general principles guiding dissemination of professional information via SoMe must remain in line with the general principles of ethics, deontology, and scientific validity that guide the medical profession and science in general. Professional equity must be maintained while communicating via SoMe. Medical practices lacking support by scientific evidence should not be disseminated. Patients\' informed consent must be obtained before dissemination of information, images, or data. Self-promotion must not be prioritized over any of these principles.
    CONCLUSIONS: When sharing medical practices and scientific information on SoMe, healthcare professionals are advised to act conscientiously and ethically. Local regulations should be adhered to. Institutional training on the potential risks and proper of SoMe for such purpose may contribute to preservation of professional integrity.
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  • 文章类型: Journal Article
    2022年欧洲心脏病学会关于非心脏手术患者心血管评估和管理的指南旨在为参与非心脏手术患者围手术期护理的医生提供服务。心脏病是并发症的潜在来源。虽然相关和有用,指南的长度可能会限制广泛阅读。这篇文章总结了指导方针,强调与医务人员为患者准备手术最相关的方面。
    The 2022 European Society of Cardiology guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery are intended for physicians involved in the perioperative care of patients undergoing non-cardiac surgery, in whom heart disease is a potential source of complications. While relevant and useful, the length of the guidelines may limit widespread reading. This article summarises the guidelines, highlighting the aspects most relevant to medical staff preparing patients for surgery.
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  • 文章类型: Journal Article
    背景:肋骨骨折与显著的发病率和死亡率相关,提供足够的镇痛对于预防这些损伤的早期并发症至关重要。多种区域麻醉技术可用于为这些损伤提供镇痛;然而,很少有基于证据的指南供他们使用。这项研究的目的是在专家组内就选择肋骨骨折区域麻醉技术时使用的选择标准达成共识。
    方法:Delphi技术是一种混合方法研究格式,它使用纵向调查过程在专家组中形成共识意见。使用在线调查平台进行了三轮修改的e-Delphi研究。第一轮确定了队列特征,并确定了该小组在选择肋骨骨折的区域麻醉技术时认为重要的关键因素。随后的几轮使用Likert量表和自由文本评论来评估参与者与第一轮回应产生的各种陈述的一致性水平。最终的共识门槛是建立的,因为至少70%的受访者表示,\'强烈不同意\'或\'不同意\'或\'同意\'或\'强烈同意\'。
    结果:招募了一个由英国麻醉和/或重症监护医学顾问组成的专家小组。参与者在各种三级和非三级创伤护理环境中工作,他们多年的经验各不相同,每年的肋骨骨折病例数和对肋骨骨折处理中各种麻醉技术的偏好。54名参与者参加了第一轮,并产生了60份陈述,并在总共三轮的迭代过程中进行了进一步分析。共有28项声明最终达到了专家组内达成共识的预定阈值。
    结论:这项e-Delphi研究成功地在与肋骨骨折患者区域麻醉选择标准相关的多个陈述中达成共识。这些共识声明可以为临床实践提供信息,指导未来的研究重点,并可以整合到跨多个医院设置的决策路径。
    BACKGROUND: Rib fractures are associated with significant morbidity and mortality, and providing adequate analgesia is paramount in preventing early complications from these injuries. Multiple regional anaesthetic techniques can be used to provide analgesia for these injuries; however, few evidence-based guidelines exist for their use. The aim of this study was to establish consensus within an expert group on the selection criteria used when choosing regional anaesthetic techniques for rib fractures.
    METHODS: The Delphi technique is a mixed-methods study format which uses a longitudinal survey process to develop consensus opinion amongst an expert group. A three-round modified e-Delphi study was undertaken using an online survey platform. Round one established cohort characteristics and identified key factors considered important by the group when selecting regional anaesthetic techniques for rib fractures. Subsequent rounds used Likert scales and free text comments to rate the participants\' level of agreement with various statements generated from the first-round responses. The final consensus threshold was established as at least 70% of respondents stating, \'Strongly Disagree\' or \'Disagree\' or alternatively \'Agree\' or \'Strongly Agree\'.
    RESULTS: An expert panel of UK-based consultants in anaesthesia and/or intensive care medicine was recruited. Participants worked in a variety of tertiary- and non-tertiary trauma care settings and were varied in their years of experience, approximate annual rib fracture caseload and preference for various anaesthetic techniques in rib fracture management. 54 participants took part in round one and generated 60 statements which were further analysed in an iterative process involving a total of three rounds. A total of 28 statements ultimately reached the pre-defined threshold for consensus within the expert group.
    CONCLUSIONS: This e-Delphi study succeeded in building consensus across multiple statements relating to the selection criteria for regional anaesthesia in patients with rib fractures. These consensus statements can inform clinical practice, guide future research priorities and can be integrated into decision-making pathways across multiple hospital settings.
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  • 文章类型: Journal Article
    围手术期用药安全是复杂的。避免用药错误既是基于系统的,也是基于医生的,医院内的许多部门都为安全有效的系统做出了贡献。对于个人麻醉师来说,起草,标签和正确的药物管理是患者围手术期的关键组成部分。这些指南旨在为手术环境中的医生和其他个人提供务实的安全步骤。以及制定减少错误的协作方法的短期到长期目标。目的是将它们用作灌输良好做法的基础。
    Peri-operative medication safety is complex. Avoidance of medication errors is both system- and practitioner-based, and many departments within the hospital contribute to safe and effective systems. For the individual anaesthetist, drawing up, labelling and then the correct administration of medications are key components in a patient\'s peri-operative journey. These guidelines aim to provide pragmatic safety steps for the practitioner and other individuals within the operative environment, as well as short- to long-term goals for development of a collaborative approach to reducing errors. The aim is that they will be used as a basis for instilling good practice.
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  • 文章类型: Consensus Development Conference
    可能需要急性住院治疗,以支持主要经历呼吸系统并发症的神经肌肉疾病(NMD)患者。吞咽困难,心力衰竭,紧急外科手术.由于NMD可能需要特定的治疗,他们应该在专科医院进行理想的管理。然而,如果需要紧急治疗,NMD患者应在最近的医院现场管理,这可能不是一个专门的中心,当地的急诊医生有足够的经验来管理这些病人。尽管NMD是一组在疾病发作方面可能不同的疾病,programming,其他系统的严重程度和参与程度,许多建议是横向的,适用于最常见的NMD。应急卡(EC)报告了关于呼吸和心脏问题的最常见建议,并提供了谨慎使用药物/治疗的适应症,在一些国家,NMD患者积极使用。在意大利,对使用任何欧共体没有共识,少数患者在紧急情况下定期服用。2022年4月,来自意大利不同中心的50名参与者在米兰会面,意大利,就紧急护理管理的最低建议达成一致,这些建议可以扩展到绝大多数NMD。研讨会的目的是就与NMD患者的急诊护理有关的主要主题达成最相关的信息和建议,以便为13个最常见的NMD产生特定的ECs。
    Acute hospitalisation may be required to support patients with Neuromuscular disorders (NMDs) mainly experiencing respiratory complications, swallowing difficulties, heart failure, urgent surgical procedures. As NMDs may need specific treatments, they should be ideally managed in specialized hospitals. Nevertheless, if urgent treatment is required, patients with NMD should be managed at the closest hospital site, which may not be a specialized centre where local emergency physicians have the adequate experience to manage these patients. Although NMDs are a group of conditions that can differ in terms of disease onset, progression, severity and involvement of other systems, many recommendations are transversal and apply to the most frequent NMDs. Emergency Cards (EC), which report the most common recommendations on respiratory and cardiac issues and provide indications for drugs/treatments to be used with caution, are actively used in some countries by patients with NMDs. In Italy, there is no consensus on the use of any EC, and a minority of patients adopt it regularly in case of emergency. In April 2022, 50 participants from different centres in Italy met in Milan, Italy, to agree on a minimum set of recommendations for urgent care management which can be extended to the vast majority of NMDs. The aim of the workshop was to agree on the most relevant information and recommendations regarding the main topics related to emergency care of patients with NMD in order to produce specific ECs for the 13 most frequent NMDs.
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  • 文章类型: Systematic Review
    Mortality, morbidity, and organ failure are important and common serious harms after surgery. However, there are many candidate measures to describe these outcome domains. Definitions of these measures are highly variable, and validity is often unclear. As part of the International Standardised Endpoints in Perioperative Medicine (StEP) initiative, this study aimed to derive a set of standardised and valid measures of mortality, morbidity, and organ failure for use in perioperative clinical trials.
    Three domains of endpoints (mortality, morbidity, and organ failure) were explored through systematic literature review and a three-stage Delphi consensus process using methods consistently applied across the StEP initiative. Reliability, feasibility, and patient-centredness were assessed in round 3 of the consensus process.
    A high level of consensus was achieved for two mortality time points, 30-day and 1-yr mortality, and these two measures are recommended. No organ failure endpoints achieved threshold criteria for consensus recommendation. The Clavien-Dindo classification of complications achieved threshold criteria for consensus in round 2 of the Delphi process but did not achieve the threshold criteria in round 3 where it scored equivalently to the Post Operative Morbidity Survey. Clavien-Dindo therefore received conditional endorsement as the most widely used measure. No composite measures of organ failure achieved an acceptable level of consensus.
    Both 30-day and 1-yr mortality measures are recommended. No measure is recommended for organ failure. One measure (Clavien-Dindo) is conditionally endorsed for postoperative morbidity, but our findings suggest that no single endpoint offers a reliable and valid measure to describe perioperative morbidity that is not dependent on the quality of deli-vered care. Further refinement of current measures, or development of novel measures, of postoperative morbidity might improve consensus in this area.
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  • 文章类型: Journal Article
    人为因素是一门基于证据的科学学科,用于安全关键行业,以改善安全和工人福祉。在麻醉中实施人为因素策略有可能减少对特殊个人和团队绩效的依赖,以提供安全和高质量的患者护理。鼓励在麻醉中采用人为因素科学,困难气道协会和麻醉师协会成立了一个工作组,包括具有人为因素专业知识和/或兴趣的麻醉师和手术室团队成员,加上一个人为因素的科学家,工业心理学家和实验心理学家/实施科学家。使用三阶段Delphi过程来制定一组12个建议:这些建议使用“控制层次结构”模型进行描述,并分类为设计,障碍,缓解措施以及教育和培训策略。尽管大多数关于人为因素的麻醉知识都涉及非技术技能,如团队合作和沟通,人为因素是一门基础广泛的科学学科,还有许多其他方面同样重要。的确,最有可能产生最大影响的人为因素策略是与安全工作环境设计有关的策略,设备和系统。虽然我们的建议主要是为麻醉师和他们合作的团队提供的,除了麻醉专业之外,其他从事医疗保健工作的人可能会有一些教训。
    Human factors is an evidence-based scientific discipline used in safety critical industries to improve safety and worker well-being. The implementation of human factors strategies in anaesthesia has the potential to reduce the reliance on exceptional personal and team performance to provide safe and high-quality patient care. To encourage the adoption of human factors science in anaesthesia, the Difficult Airway Society and the Association of Anaesthetists established a Working Party, including anaesthetists and operating theatre team members with human factors expertise and/or interest, plus a human factors scientist, an industrial psychologist and an experimental psychologist/implementation scientist. A three-stage Delphi process was used to formulate a set of 12 recommendations: these are described using a \'hierarchy of controls\' model and classified into design, barriers, mitigations and education and training strategies. Although most anaesthetic knowledge of human factors concerns non-technical skills, such as teamwork and communication, human factors is a broad-based scientific discipline with many other additional aspects that are just as important. Indeed, the human factors strategies most likely to have the greatest impact are those related to the design of safe working environments, equipment and systems. While our recommendations are primarily provided for anaesthetists and the teams they work with, there are likely to be lessons for others working in healthcare beyond the speciality of anaesthesia.
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  • 文章类型: Journal Article
    许多护士仍然熟悉传统上给准备接受手术的患者的指令“从午夜开始口服”。国家和国际指南现在提倡缩短术前禁食时间,封装在\'2-4-6规则\'-两个小时的透明液体,母乳四个小时,固体六个小时。最新的证据似乎表明,这些禁食时间需要修订。此外,指南的实施方式存在不一致之处。本文探讨了有关成人和儿童术前禁食的指南和文献,以确定证据是什么以及可以进行哪些更改以确保一致,高质量的病人护理。
    Many nurses will still be familiar with the instruction \'nil by mouth from midnight\' traditionally given to patients preparing to undergo surgery. National and international guidelines now promote much shorter preoperative fasting times, encapsulated in the \'2-4-6 rule\' - two hours for clear fluids, four hours for breast milk and six hours for solids. The latest evidence appears to show that these fasting times are in need of revision. Furthermore, there are inconsistencies in how guidelines are implemented. This article explores the guidelines and literature on preoperative fasting in adults and children to determine what the evidence is and what changes could be made to ensure consistent, high-quality patient care.
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  • 文章类型: Journal Article
    指导文件是临床医生指导循证决策的宝贵资源。麻醉和其他专业的指南质量已被证明很差。COVID-19迫切需要立即指导麻醉师作为一线临床医生。本研究的目的是使用国际认可的研究与评估指南评估(AGREE)II工具评估COVID-19指导文件的质量。
    在OvidEMBASE和OvidMEDLINE进行了搜索,以确定2020-2021年的所有COVID-19麻醉指导文件。选择了38份指导文件,由4名独立评估师使用AGREEII工具进行分析,跨越其6个领域和23个项目。工作组通过协商一致同意了高质量的评分阈值。
    总的来说,COVID-19指导文件的正文在使用AGREEII时得分较差。只有5%的文件符合高质量标准。质量标志包括国际和多机构合作。文档标题(\'指南\'与\'共识声明\'/\'建议\')在领域得分和总体质量评级方面没有任何差异。与最近的全身麻醉指南相比,COVID-19指南的表现明显更差。
    在大流行的头两年发布的COVID-19指导文件缺乏严谨性和适当的质量。这引起了人们对它们在临床实践中使用的可信度的担忧。需要增强系统,以确保快速制定的指南的完整性。
    Guidance documents are a valuable resource to clinicians to guide evidenced-based decision making. The quality of guidelines in anaesthesia and across other specialties has been demonstrated to be poor. COVID-19 presented an urgent need for immediate guidance for anaesthetists as frontline clinicians. The aim of this study was to evaluate the quality of COVID-19 guidance documents using the internationally validated Appraisal of Guidelines for Research & Evaluation (AGREE) II tool.
    A search was conducted in Ovid EMBASE and Ovid MEDLINE to identify all COVID-19 anaesthesia guidance documents from 2020-2021. Thirty-eight guidance documents were selected for analysis by 4 independent appraisers using the AGREE II instrument, across its 6 domains and 23 items. A scoring threshold for high quality was agreed by the working group via consensus.
    Overall, the body of COVID-19 guidance documents achieved poor scores using AGREE II. Only 5% of documents met the high-quality criteria. Markers of quality included international and multi-institutional collaboration. Document title (\'guideline\' vs \'consensus statement\'/ \'recommendations\') did not yield any differences in domain scores and overall quality ratings. Compared with recent general anaesthesia guidelines, COVID-19 guidelines performed significantly worse.
    COVID-19 guidance documents published during the first two years of the pandemic lacked rigour and appropriate quality. This raises concern about their trustworthiness for use in clinical practice. Enhanced systems are required to ensure the integrity of rapidly formulated guidance.
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