■有氧运动(AE)干预措施开始被用作治疗注意力缺陷多动障碍(ADHD)儿童的新兴辅助治疗方式。然而,到目前为止,没有大量证据支持有氧运动干预对6-12岁多动症儿童的改善效果.本研究旨在探讨有氧运动疗法对6~12岁注意缺陷多动障碍儿童执行功能的影响。
■我们使用PubMed和WebofScience进行了系统综述和荟萃分析。截止日期为2023年6月1日。目的是评估有氧运动干预对ADHD儿童的影响,并纳入所有符合ADHD儿童有氧运动干预条件的随机对照试验。9项随机对照试验筛选了系统评价的资格。9项研究采用PEDro评分和GRADE证据质量评价系统对结果指标进行质量分级,评估偏倚风险。在测试了异质性之后,选择随机效应模型进行分析.最后,对核心功能进行荟萃分析和回归分析(抑制控制,认知灵活性,和工作记忆)以及使用Revman5.4和Stata16.0进行的九项执行功能研究的亚组。
■偏倚风险评估显示平均PEDro评分为7.78,在9项研究中,两个被评为具有优异的方法学质量,而其余7人都有很好的证据,GRADE证据评价结果指标均为中等质量。抑制控制[SMD=0.83,95%CI(0.37-1.29),Z=3.51,p=0.0005],认知灵活性[SMD=0.65,95%CI(0.37-0.93),Z=4.58,p<0.00001],和工作记忆[SMD=0.48,95%CI(0.02-0.95),Z=2.03,p=0.04]具有统计学意义,具有中等或更高的效果大小;此外,在亚组分析干预类型中,持续时间,强度,药物使用对抑制控制和认知灵活性有不同的影响,和组合的IC,CF统计发现,单类有氧运动(β=0.867,p<0.001),中等强度(β=0.928,p<0.001),6-12周(β=0.804,p<0.001),60-90分钟(β=0.894,p<0.001),使用药物(β=1.202,p=0.002)对EF的总体改善更好。
■有氧运动疗法显著改善多动症儿童的执行功能,表现出中等以上的效应大小,特别是在抑制控制中,认知灵活性,和工作记忆。有氧运动疗法可作为改善ADHD患儿执行功能的参考,但是鉴于这项研究的局限性,临床应用时应谨慎使用.
UNASSIGNED: Aerobic exercise (AE) interventions are beginning to be used as an emerging adjunctive treatment modality in the treatment of children with Attention Deficit Hyperactivity Disorder (ADHD). However, to date, there is no substantial evidence to support the improved effects of aerobic exercise intervention in children with ADHD aged 6-12 years. This study aims to investigate the effect of aerobic exercise therapy on executive function in children with attention deficit hyperactivity disorder aged 6-12 years.
UNASSIGNED: We conducted a systematic review and meta-analysis using PubMed and Web of Science. The cut-off date was June 1, 2023. The aim was to assess the impact of aerobic exercise interventions on children with ADHD and all randomized controlled trials eligible for aerobic exercise interventions for children with ADHD were included. Nine randomized controlled trials were screened for eligibility for systematic evaluation, and the nine studies were assessed for risk of bias using the PEDro score and the GRADE Quality of Evidence Evaluation System for quality grading of outcome indicators. After testing for heterogeneity, a random-effects model was selected for analysis. Finally, meta-analyses and regression analyses were performed on the core functions (inhibitory control, cognitive flexibility, and working memory) and subgroups of the nine studies on executive function using Revman 5.4 and Stata 16.0.
UNASSIGNED: The risk of bias evaluation showed a mean PEDro score of 7.78, and of the nine studies, two were rated as having excellent methodological quality, while the remaining seven had a good level of evidence, and the GRADE evidence evaluation showed that the outcome indicators were all of moderate quality. Inhibitory control [SMD = 0.83,95% CI (0.37-1.29), Z = 3.51, p = 0.0005], cognitive flexibility [SMD = 0.65,95% CI (0.37-0.93), Z = 4.58, p < 0.00001], and working memory [SMD = 0.48,95% CI (0.02-0.95), Z = 2.03, p = 0.04] were statistically significant, with effect sizes of moderate or higher; furthermore, in subgroup analyses type of intervention, duration, intensity, and medication use had different effects on inhibitory control and cognitive flexibility, and the combined IC, CF statistic found that a single category of aerobic exercise ( β = 0.867, p < 0.001), moderate intensity ( β = 0.928, p < 0.001), 6-12 weeks (β = 0.804, p < 0.001), 60-90 min ( β = 0.894, p < 0.001), and the use of medication ( β = 1.202, p = 0.002) were better for overall improvement in EF.
UNASSIGNED: Aerobic exercise therapy significantly improved executive functioning in children with ADHD, showing above moderate effect sizes especially in inhibitory control, cognitive flexibility, and working memory. Aerobic exercise therapy can be used as a reference in improving executive function in children with ADHD, but given the limitations of this study, it should be used with caution when applied in clinical settings.