PDF(Pubmed)
Abstract：
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation. The purpose of this systematic review is to evaluate the effectiveness of exercise training on functional capacity and quality of life (QoL) in patients with RA. We performed a search in four databases, selecting clinical trials that included community or outpatient exercise training programs in patients with RA. The primary outcome was functional capacity assessed by peak VO2 or the 6 min walking test, and the secondary outcome was QoL assessed by questionnaires. Seven studies were finally included, identifying a total number of 448 patients. The results of the present systematic review show a statistically significant increase in peak VO2 after exercise training in four out of seven studies. In fact, the improvement was significantly higher in two out of these four studies compared to the controls. Six out of seven studies provided data on the patients\' QoL, with five of them managing to show statistically significant improvement after exercise training, especially in pain, fatigue, vitality, and symptoms of anxiety and depression. This systematic review demonstrates the beneficial effects of exercise training on functional capacity and QoL in patients with RA.
摘要：
类风湿性关节炎(RA)是一种以慢性炎症为特征的自身免疫性疾病。这项系统评价的目的是评估运动训练对RA患者功能能力和生活质量（QoL）的有效性。我们在四个数据库中进行了搜索，选择包含RA患者社区或门诊运动训练计划的临床试验.主要结果是通过峰值VO2或6分钟步行测试评估的功能能力。次要结局是通过问卷评估的QoL。最终纳入了七项研究，确定总共448名患者。本系统评价的结果表明，在七项研究中的四项中，运动训练后峰值VO2在统计学上显着增加。事实上,与对照组相比,4项研究中有2项的改善程度显著高于对照组.七项研究中有六项提供了患者QoL的数据，其中五人在运动训练后表现出统计学上的显着改善，尤其是在疼痛中，疲劳,活力,还有焦虑和抑郁的症状.这项系统评价证明了运动训练对RA患者功能能力和QoL的有益影响。
