含有生物活性化合物的食物,叫做营养食品,可以对抗或预防或缓解疾病。营养品或植物化学物质对非侵入性生物医学应用的贡献正在增加。虽然提取生物活性化合物或次生代谢产物的传统方法很多,这些过程有许多缺点,如产率低,较长的处理时间,能耗高,更多使用溶剂,产生低活性原则,对疾病的功效低,质量差,传质不良,较高的提取温度,等。然而,消除非热技术的所有这些缺点,超声在提高产量和改善生物功效方面发挥了重要作用。声空化的物理和化学效应是输出的症结。这篇综述论文主要讨论了生物活性物质的超声辅助提取(USAE)在人类和动物模型中提供对疾病和身体功能障碍的非侵入性预防和治疗。详细讨论了非侵入性生物活性成分在体外或体外条件下的产量和临床功效方面的输出。USAE生物活性物质提供抗癌的非侵入性生物医学应用,抗氧化剂,心血管健康,抗糖尿病药,和抗菌效益进行了深入分析和评价。这篇综述还强调了USAE化合物对常规提取化合物的改进性能。此外,对食品生物活性物质在体内和体外系统中的作用和应用进行了详尽的分析,主要用于在非侵入性生物医学应用中推广这些有效的USAE生物活性物质。此外,这篇评论探讨了从仙人掌梨果实等较少探索的食物来源中回收生物活性物质,灰葫芦,甜花岗岩,罗勒,kokum,猴面包树,和食品加工工业废物,如果皮,果渣,蜂胶,葡萄酒残留物,麸皮,等。,这在文学中是罕见的。
Foods incorporated with bioactive compounds, called nutraceuticals, can fight or prevent or alleviate diseases. The contribution of nutraceuticals or phytochemicals to non-invasive biomedical applications is increasing. Although there are many traditional methods for extracting bioactive compounds or secondary metabolites, these processes come with many disadvantages like lower yield, longer process time, high energy consumption, more usage of solvent, yielding low active principles with low efficacy against diseases, poor quality, poor mass transfer, higher extraction temperature, etc. However, nullifying all these disadvantages of a non-thermal technology, ultrasound has played a significant role in delivering them with higher yield and improved bio-efficacy. The physical and chemical effects of acoustic cavitation are the crux of the output. This
review paper primarily discusses the ultrasound-assisted extraction (USAE) of bioactives in providing non-invasive prevention and cure to diseases and bodily dysfunctions in human and animal models. The outputs of non-invasive bioactive components in terms of yield and the clinical efficacy in either in vitro or in vitro conditions are discussed in detail. The non-invasive biomedical applications of USAE bioactives providing anticancer, antioxidant, cardiovascular health, antidiabetic, and antimicrobial benefits are analyzed in-depth and appraised. This
review additionally highlights the improved performance of USAE compounds against conventionally extracted compounds. In addition, an exhaustive analysis is performed on the role and application of the food bioactives in vivo and in vitro systems, mainly for promoting these efficient USAE bioactives in non-invasive biomedical applications. Also, the
review explores the recovery of bioactives from the less explored food sources like cactus pear fruit, ash gourd, sweet granadilla, basil, kokum, baobab, and the food processing industrial wastes like peel, pomace, propolis, wine residues, bran, etc., which is rare in literature.