Surgical Site Infection

手术部位感染
  • 文章类型: Case Reports
    我们提供了一例病例报告,该病例报告是一名26岁的女性在双侧隆胸后感染了wolinskyi分枝杆菌手术部位。与以前报道的病例相比,这是一种独特的方法,该患者在门诊仅口服复方复方新诺明(甲氧苄啶-磺胺甲恶唑)和环丙沙星并单侧保留乳房假体治疗成功.我们还提供截至2023年12月在PubMed数据库中提供的所有wolinskyi感染报告病例的全面概述,并比较不同的诊断和治疗方法。
    We present a case report about a 26-year-old female with a Mycobacterium wolinskyi surgical site infection after bilateral breast augmentation. In a unique approach compared with previously reported cases, the patient was successfully treated in an outpatient setting using only orally administered cotrimoxazole (trimethoprim-sulfamethoxazole) and ciprofloxacin with one-sided preservation of the breast prothesis. We also provide a comprehensive overview of all report cases of M. wolinskyi infections available in the PubMed database until December 2023 and compare the different diagnostic and therapeutic approaches.
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  • 文章类型: Case Reports
    金黄色葡萄球菌与血管炎的关联仍然相对罕见且知之甚少。在这份报告中,我们介绍了一例甲氧西林敏感性金黄色葡萄球菌(MSSA)相关白细胞碎裂性血管炎(LCV)手术部位感染后,增加了对这个有趣的临床实体的有限知识。一名52岁男性,有明显的2型糖尿病病史,高血压,高脂血症,冠状动脉疾病表现为逐渐恶化的泛发性斑疹和偏头痛伴关节肿胀。患者的症状开始于腹直肌切口疝手术修复后,并放置网片,在手术部位并发腹壁脓肿。提示排水沟放置。来自脓肿抽吸物的培养物显示甲氧西林敏感的金黄色葡萄球菌感染。对瘀点病变的穿刺活检显示发现与白细胞碎裂性血管炎一致。皮疹和关节痛在开始抗生素和类固醇治疗后约一周缓解。该病例揭示了甲氧西林敏感性金黄色葡萄球菌感染与白细胞碎裂性血管炎之间罕见但具有临床意义的关联,特别是在手术部位感染之后。及时识别和治疗潜在的MSSA感染,随着LCV的目标管理,导致我们的患者症状的解决。该病例强调了综合诊断方法的重要性,并强调了抗生素治疗在减轻MSSA相关血管病变表现方面的功效。
    The association of Staphylococcus aureus with vasculitis remains relatively rare and poorly understood. In this report, we present a case of Methicillin-sensitive Staphylococcus aureus (MSSA)-associated leukocytoclastic vasculitis (LCV) following a surgical site infection, adding to the limited body of knowledge on this intriguing clinical entity. A 52-year-old male with a medical history significant for type 2 diabetes mellitus, hypertension, hyperlipidemia, and coronary artery disease presented with progressively worsening generalized petechial rash and migratory joint pains with associated joint swelling. The patient\'s symptoms began following surgical repair for a rectus abdominis incisional hernia with mesh placement that was complicated by an abdominal wall abscess at the surgical site, prompting drain placement. Cultures from the abscess aspirate revealed Methicillin-sensitive Staphylococcus aureus infection. A punch biopsy of the petechial lesions revealed findings consistent with leukocytoclastic vasculitis. The rash and joint pains resolved approximately one week after initiation of treatment with antibiotics and steroids. This case sheds light on the rare but clinically significant association between Methicillin-sensitive Staphylococcus aureus infection and leukocytoclastic vasculitis, particularly following surgical site infections. The prompt recognition and treatment of underlying MSSA infection, along with the targeted management of LCV, resulted in the resolution of symptoms in our patient. This case emphasizes the importance of a comprehensive diagnostic approach and highlights the efficacy of antibiotic therapy in mitigating MSSA-associated vasculitic manifestations.
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  • 文章类型: Case Reports
    该报告详细介绍了一名53岁的IgA-κ型多发性骨髓瘤患者在异基因造血干细胞移植(allo-HSCT)后由kansasii分枝杆菌引起的手术部位感染(SSI)的罕见病例。在接受多种化疗方案和两次干细胞移植后,患者在移植后31个月出现了SSI,在先前的开颅手术部位表现为颅内脓肿。从引流液中分离出了Kansasii分枝杆菌,在具有这种延迟发作的allo-HSCT后NTM感染的文献中,将此病例标记为独特病例。患者的治疗包括基于药敏试验的靶向抗菌治疗,最终导致感染的解决,尽管患者后来死于多发性骨髓瘤复发。该病例强调了在免疫功能低下患者的持续性发烧和SSIs的鉴别诊断中,必须考虑NTM感染。尤其是那些患有慢性移植物抗宿主病的患者。它强调了早期诊断和治疗干预措施对有效管理这些感染的重要性。本报告有助于有限但越来越多的关于NTM感染后allo-HSCT的文献,并强调在监测术后患者时需要保持警惕。尤其是那些长期免疫抑制的人。
    This report details a rare case of surgical site infection (SSI) caused by Mycobacterium kansasii following allogeneic hematopoietic stem cell transplantation (allo-HSCT) in a 53-year-old patient with IgA-κ type multiple myeloma. After undergoing multiple chemotherapy regimens and two stem cell transplants, the patient developed an SSI 31-month post-transplantation, manifesting as an intracranial abscess at the site of a previous craniotomy. M. kansasii was isolated from the drainage fluid, marking this instance as a unique case in the literature of nontuberculous mycobacteria (NTM) infection post-allo-HSCT with such a delayed onset. The patient\'s treatment included targeted antimicrobial therapy based on susceptibility testing, resulting in eventual resolution of the infection, although the patient later succumbed to multiple myeloma relapse. This case underscores the critical need to consider NTM infections in the differential diagnosis of persistent fevers and SSIs in immunocompromised patients, particularly those with chronic graft-versus-host disease. It highlights the importance of early diagnostic and therapeutic interventions to manage these infections effectively. This report contributes to the limited but growing body of literature on NTM infections post-allo-HSCT and emphasizes the need for vigilance in monitoring postoperative patients, especially those with prolonged immunosuppression.
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  • 文章类型: Case Reports
    我们介绍了一例43岁女性艰难梭菌(CD)引起的输卵管卵巢脓肿(TOA)。尽管缺乏性传播疾病的病史,患者在入院前9个月接受了卵巢旁膀胱切除术.术后8个月经阴道超声检查显示左卵巢增大,随后伴有下腹痛和超过38°C的发烧。由于口服抗生素治疗无效,病人入院。入院时的计算机断层扫描显示出巨大的TOA。进行脓肿的外科引流,在脓液的培养物中鉴定出CD。TOA用甲硝唑和口服阿莫西林/克拉维酸治疗三个月的疗程。虽然CD通常与结肠炎有关,肠外表现异常罕见.此案例代表了CD产生的TOA的就职报告。关于腹部和盆腔CD脓肿的文献综述发现,接受手术引流的患者预后良好。因此,手术干预在CD脓肿的治疗中起着重要作用。
    We present a case of tubo-ovarian abscess (TOA) caused by Clostridioides difficile (CD) in a 43-year-old female. Despite lacking a history of sexually transmitted diseases, the patient had undergone paraovarian cystectomy nine months before admission. Transvaginal ultrasonography performed eight months post-surgery revealed left ovarian enlargement, accompanied by subsequent lower abdominal pain and fever exceeding 38 °C. As oral antibiotic treatment was ineffective, the patient was admitted to our hospital. Computed tomography upon admission revealed a massive TOA. Surgical drainage of the abscess was performed, and CD was identified in the culture from the pus. The TOA was treated with a three-month course of metronidazole and oral amoxicillin/clavulanic acid. While CD is commonly associated with colitis, extraintestinal manifestations are exceptionally rare. This case represents the inaugural report of TOA resulting from CD. A literature review on abdominal and pelvic CD abscesses found that patients undergoing surgical drainage had a favorable prognosis. Therefore, surgical intervention plays an important role in the management of CD abscesses.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Case Reports
    人类sc疮是由Sarcoptesscabiei螨引起的传染性皮肤病,导致皮肤损伤和随后的机械刺激刮伤。这种受损的皮肤完整性使个体易于皮肤感染。虽然由金黄色葡萄球菌和化脓性链球菌引起的sc疮和皮肤感染之间的关联是有据可查的,关于此类病例中手术部位感染风险的文献有限.
    方法:本病例报告旨在探讨这一风险,该病例是一例在1例sc疮感染患者的复杂肘部损伤手术后由化脓性链球菌引起的手术部位感染。
    结论:镰刀菌感染导致细菌的直接传播,并有助于细菌感染。此外,由sc疮引起的补体抑制和菌群失调可能会促进这些细菌感染的发生。
    结论:皮肤感染经常发生在sc疮感染中。手术前应仔细评估首选切口。需要进一步的研究才能就此问题得出明确的结论。
    UNASSIGNED: Human scabies is a contagious skin condition caused by the Sarcoptes scabiei mite, leading to skin damage and subsequent mechanical irritation from scratching. This impaired skin integrity predisposes individuals to skin infections. While the association between scabies and skin infections caused by Staphylococcus aureus and Streptococcus pyogenes is well-documented, there is limited literature on the risk of surgical site infections in such cases.
    METHODS: This case report aims to explore this risk by presenting a case of surgical site infection caused by Streptococcus pyogenes following surgery for a complex elbow injury in a patient with scabies infestation.
    CONCLUSIONS: Scabies infestation leads to direct spread of bacteria and contributes to bacterial infection. Furthermore, complement inhibition and dysbiosis induced by the scabies may facilitate the occurrence of these bacterial infections.
    CONCLUSIONS: Skin infections are frequently encountered in scabies infestations. Preferred incision should be evaluated meticulously before surgery. Further studies are needed to reach a definitive conclusion on this subject.
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  • 文章类型: Case Reports
    脊髓硬膜外脓肿(SEA)是一种罕见的疾病,可能导致灾难性的后果。另一方面,焦磷酸钙(CPP)沉积疾病(CPPD)引起炎性关节炎。由CPPD引起的晶体诱导的炎症的脊柱受累也很常见。手术是SEA和CPPD的常见危险因素;然而,SEA并发CPPD的术后急性发作极为罕见。
    一位70多岁的男子来到我们医院,抱怨右上肢无力,失去灵巧,和步态紊乱。诊断为脊髓型颈椎病,他在C3,C4和C5水平进行了椎板切除术。椎板切除术后四天,他患有急性颈部疼痛,弱点,他的胳膊和腿感觉减退。磁共振成像显示肿块占据了C6和C7的硬膜外背侧间隙,压迫了颈脊髓。考虑到急性症状,手术后怀疑急性脊髓硬膜外血肿;因此,实施了紧急C6和C7椎板切除术.手术结果表明椎管内压力升高,肿块是脓性渗出物。病理检查显示化脓性炎症并伴有CPP沉积。考虑了SEA与CPPD的复杂性;因此,给予抗生素和非甾体抗炎药.尽管他的灵活性略有残留,但运动无力和感觉减退得到了改善。
    宫颈手术后SEA并发CPPD急性发作的报道很少。由晶体诱导的炎症引起的化脓性炎症可能是急性症状学的原因。
    UNASSIGNED: Spinal epidural abscess (SEA) is a rare condition that may result in catastrophic outcomes. On the other hand, calcium pyrophosphate (CPP) deposition disease (CPPD) causes inflammatory arthritis. Spinal involvement of a crystal-induced inflammation caused by CPPD is also common. Surgery is a common risk factor for both SEA and CPPD; however, the postoperative acute onset of SEA complicated with CPPD is extremely rare.
    UNASSIGNED: A man in his 70s presented to our hospital, complaining of right upper limb weakness, loss of dexterity, and gait disturbance. The diagnosis of cervical spondylotic myelopathy was made, and he performed laminectomy at C3, C4, and C5 levels. Four days after the laminectomy, he suffered from acute neck pain, weakness, and hypoesthesia in his arms and legs. Magnetic resonance imaging revealed a mass occupying the dorsal epidural space of C6 and C7, compressing the cervical spinal cord. Considering the acute symptomatology, an acute spinal epidural hematoma after surgery was suspected; therefore, emergency C6 and C7 laminectomy was performed. Surgical findings indicated that the pressure inside the spinal canal was elevated, and the mass was purulent exudate. Pathological examination showed suppurative inflammation with concomitant deposition of CPP. SEA complicated with CPPD was considered; therefore, antibiotics and non-steroidal anti-inflammatory drugs were administered. The motor weakness and hypoesthesia were improved despite a slight residual deficit in his dexterity.
    UNASSIGNED: An acute onset of SEA complicated with CPPD after cervical surgery has rarely been reported. The suppurative inflammation fostered by the crystal-induced inflammation may account for the acute symptomatology.
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  • 文章类型: Case Reports
    COVID-19感染后,胸骨脱位和伤口裂开导致感染,使双侧肺移植后免疫抑制患者的康复复杂化。乳状浑浊的伤口分泌物的厌氧培养(96小时)导致了确定为人前支原体(以前的人型支原体)的精确溶血菌落的生长。寻找感染的内源性来源发现细菌仅在患者的痰中,与供体肺人源支原体定植有可能的联系。不幸的是,供体样本不再可用。尽管在治疗结束后连续PCR检测到痰中的人型支原体,但用克林霉素成功治疗了17天的伤口感染。
    Following the COVID-19 infection, the sternum dislocation and wound dehiscence resulted in an infection complicating the recovery of an immunosuppressed patient after bilateral lung transplantation. Anaerobic culture (96 h) of milky cloudy wound secretion resulted in the growth of pinpoint haemolytic colonies identified as Metamycoplasma hominis (formerly Mycoplasma hominis). The search for the endogenous source of the infection found the bacterium exclusively in the patient\'s sputum, making a possible link to donor lung M. hominis colonization. Unfortunately, the donor samples were no longer available. The wound infection was successfully treated with 17 days of clindamycin despite the continuous PCR detection of M. hominis in the sputum after the end of the treatment.
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  • 文章类型: Journal Article
    本病例系列的目的是分析在三级医疗机构进行的气管造口术在两年时间内引起的并发症。在研究的100例气管切开术中,观察到15例并发症的发生,表明患病率为15%。检测到的并发症包括皮下气肿,管子的错位,手术部位的感染,气管狭窄,在各种其他人中。确定了相当多的并发症迹象,包括年龄和头颈癌病史等变量。这项研究的结果突出了个性化病人护理的意义,警惕监测,以及对接受气管造口术的个人采取的积极措施。需要进一步的研究来验证这些发现并提高患者的安全性和气管造口术领域的预后。
    The objective of this case series was to analyse the complications that arise from tracheostomy procedures conducted in a tertiary healthcare facility throughout a two-year timeframe. Fifteen occurrences of complications were observed out of the 100 tracheostomies that were studied, suggesting a prevalence rate of 15%. The detected complications included subcutaneous emphysema, misplacement of the tube, infection at the surgical site, and tracheal stenosis, among various others. Considerable indications of complication were identified, encompassing variables such as age and a history of head and neck cancer. The findings of this study highlight the significance of personalized patient care, vigilant monitoring, and proactive measures for individuals receiving tracheostomy. Further investigations are necessary to validate these findings and improve patient safety and outcomes in the realm of tracheostomy surgeries.
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  • 文章类型: Journal Article
    手术部位感染是一种常见的医疗保健相关感染,会影响产妇健康,但它是可以预防或控制的。剖腹产最可能发生手术部位感染。据报道,剖腹产的分娩率高于某些医疗机构的可接受率。可以识别和修改手术部位感染的危险因素,以减少手术部位感染的发生。这项研究旨在确定肯尼亚三级教学医院剖腹产后导致手术部位感染的危险因素。
    这是一项回顾性病例对照(1:2匹配)研究,于2021年11月1日至2022年10月31日在内罗毕的一家三级医院进行。根据世界卫生组织推荐的术前措施提取手术部位危险因素数据,对于这两种情况和控制。使用描述性统计来总结变量,并使用卡方检验和Fisher精确检验进行组比较。
    总共进行了1,262次剖腹产手术,其中2.1%(27/1262)在剖腹产后发生手术部位感染。确定的危险因素与手术部位感染的发展没有显着相关(胎龄P=0.152,体重指数P=0.615,胎膜早破P=0.253,抗生素预防P=0.108)。
    尽管存在积极趋势,但手术部位感染危险因素与手术部位感染没有显著关联。除了图表审查外,还应使用其他前瞻性方法来确定每个危险因素对手术部位感染的影响程度。
    UNASSIGNED: Surgical site infection is a common healthcare-associated infection that affects maternal health, yet it can be prevented or controlled. Caesarian sections are most likely to develop surgical site infections. The rates of delivery by caesarian section in reported to be higher that the acceptable rates in some healthcare facilities. Risk factors for surgical site infections can be identified and modified to reduce the occurrence of surgical site infections. This study aims to determine the risk factors that contribute to surgical site infections post caesarian section in a tertiary teaching hospital in Kenya.
    UNASSIGNED: This was a retrospective case-control (1:2 matched) study conducted between 1st November 2021 to 31st October 2022 at a tertiary hospital in Nairobi. Data was extracted on surgical site risk factors as per World Health Organization\'s recommended preoperative measures, for both cases and controls. Descriptive statistics was used to summarize the variables and the Chi-squared test and Fisher\'s Exact test were used for group comparisons.
    UNASSIGNED: A total of 1,262 caesarian deliveries were performed, 2.1% (27/1262) of which developed surgical site infections post caesarian section. The risk factors identified were not significantly associated with surgical site infection development (gestational age P=0.152, body mass index P=0.615, premature rupture of membranes P=0.253, and antibiotic prophylaxis P=0.108).
    UNASSIGNED: There was no significant association of exposure to surgical site infection risk factors with surgical site infection despite a positive trend. Other prospective methods should also be used in addition to chart reviews to determine the level of effect each risk factor has on surgical site infection.
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