关键词: Mycoplasma hominis Cardiothoracic surgery Clindamycin Lung transplantation Surgical site infection Wound infection

Mesh : Humans Lung Transplantation / adverse effects Surgical Wound Infection / microbiology drug therapy diagnosis Mycoplasma hominis / genetics isolation & purification Mycoplasma Infections / microbiology diagnosis drug therapy Male COVID-19 / diagnosis Anti-Bacterial Agents / therapeutic use Sputum / microbiology Middle Aged SARS-CoV-2 / genetics isolation & purification Immunocompromised Host Clindamycin / therapeutic use

来  源:   DOI:10.1007/s12223-024-01160-5

Abstract:
Following the COVID-19 infection, the sternum dislocation and wound dehiscence resulted in an infection complicating the recovery of an immunosuppressed patient after bilateral lung transplantation. Anaerobic culture (96 h) of milky cloudy wound secretion resulted in the growth of pinpoint haemolytic colonies identified as Metamycoplasma hominis (formerly Mycoplasma hominis). The search for the endogenous source of the infection found the bacterium exclusively in the patient\'s sputum, making a possible link to donor lung M. hominis colonization. Unfortunately, the donor samples were no longer available. The wound infection was successfully treated with 17 days of clindamycin despite the continuous PCR detection of M. hominis in the sputum after the end of the treatment.
摘要:
COVID-19感染后,胸骨脱位和伤口裂开导致感染,使双侧肺移植后免疫抑制患者的康复复杂化。乳状浑浊的伤口分泌物的厌氧培养(96小时)导致了确定为人前支原体(以前的人型支原体)的精确溶血菌落的生长。寻找感染的内源性来源发现细菌仅在患者的痰中,与供体肺人源支原体定植有可能的联系。不幸的是,供体样本不再可用。尽管在治疗结束后连续PCR检测到痰中的人型支原体,但用克林霉素成功治疗了17天的伤口感染。
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