■色素性紫癜性皮肤病(PPD)被称为慢性复发性喷发,通常表现为下肢的瘀点和色素性黄斑。皮肤镜检查是一种非侵入性诊断工具,用于识别色素沉着和血管病变。这也有助于PPD的评估。
■我们旨在分析PPD的常见皮肤特征,并将这些发现与组织病理学特征相关联。此外,本研究人群的皮肤镜和病理结果与文献综述中的其他类似研究进行了比较。
■对60例经皮肤活检诊断为PPD的患者进行回顾性分析。通过将模式分类为苔藓样进行病理分析,血管周围,接口,和海绵状亚型,皮肤镜评估由三位作者独立进行.
■在皮肤镜检查中,96.7%的患者出现红色小球和点,接着是褐色的补丁,铜红色色素沉着,和环状逗号状血管。病理模式分析显示,苔藓样模式与铜红色色素沉着具有统计学意义。环状/逗号样血管的血管周围模式,网状色素沉着网络和线性血管的海绵状形态。评估者间相似性检验显示总kappa值为0.811,指“非常好”。
■在这项研究中,确定了亚洲PPD患者的皮肤镜特征的患病率,这与以前的研究相似。在四个皮肤镜特征中发现了皮肤镜与病理的相关性。我们建议皮肤镜检查有助于PPD的临床诊断和病理预测。
UNASSIGNED: Pigmented purpuric dermatosis (PPD) is known as a chronic recurrent eruption which usually presents with petechiae and pigmented macules on the lower extremities. Dermoscopy is a noninvasive diagnostic tool in identifying pigmented and vascular lesions, which can also be beneficial in the evaluation of PPD.
UNASSIGNED: We aimed to analyze the common dermoscopic characteristics of PPD, and correlate those findings with the histopathologic features. Additionally, dermoscopic and pathological findings in this study population were compared with other similar studies from the literature
review.
UNASSIGNED: A retrospective analysis was performed using data of 60 patients who were diagnosed as PPD by skin biopsy and had dermoscopic examination. The pathologic analysis was performed by categorizing the pattern into lichenoid, perivascular, interface, and spongiotic subtype, and the dermoscopic assessment was performed by the three authors independently.
UNASSIGNED: In dermoscopy, 96.7% of the patients showed red globules and dots, followed by brownish patch, coppery-red pigmentation, and annular comma-like vessels. The pathologic pattern analysis revealed statistically significant association of lichenoid pattern with coppery red pigmentation, perivascular pattern with annular/comma-like vessels, and spongiosis pattern with reticular pigmented network and linear vessels. The interrater similarity test showed total kappa value of 0.811 which referred to \"very good\".
UNASSIGNED: In this study, the prevalence of dermoscopic features in Asian PPD patients was identified, which was similar with previous studies. The dermoscopic-pathologic correlation was found in four dermoscopic features. We suggest that dermoscopic examination is helpful in clinical diagnosis and pathological prediction of PPD.