Abstract：
UNASSIGNED: Cutaneous collagenous vasculopathy (CCV) is a rare and idiopathic microangiopathy of superficial dermal blood vessels. There have been 75 cases described in the literature to date, not including the current report; however, given its clinical similarity to other primary telangiectasias, it is likely to be underreported and underdiagnosed. Here, we describe the clinical and histological features of 2 patients we newly diagnosed with CCV. Both generally fit the profile of prior cases and confirm previously described associations-they both are older White women, have rashes on their lower extremities, and have conditions and medications that are common among other reported cases. However, both are also somewhat atypical, as Patient 1 had symptomatic CCV and Patient 2 had a papular rash. As such, both cases broaden the spectrum of our current understanding of CCV. We also provide a comprehensive review of all published reports of CCV to date and uncover 2 previously unreported associations: one with visceral malignancy, and the other with hypothyroidism. Whether these association are coincidental is worth investigating in future studies.
摘要：
■皮肤胶原性血管病变（CCV）是一种罕见的特发性浅层皮肤血管微血管病变。迄今为止，文献中已经描述了75例病例，不包括本报告；然而，鉴于其与其他原发性毛细血管扩张的临床相似性，它很可能被低估和诊断不足。这里,我们描述了我们新诊断为CCV的2例患者的临床和组织学特征。两者通常都符合先前病例的概况，并确认了先前描述的关联-他们都是年长的白人女性，他们的下肢有皮疹，并且有其他报告病例中常见的疾病和药物。然而,两者也有点不典型，患者1有症状CCV，患者2有丘疹。因此，这两种情况都拓宽了我们目前对CCV的理解范围。我们还对迄今为止所有已发表的CCV报告进行了全面审查，并发现了2个以前未报告的关联：一个与内脏恶性肿瘤，另一种是甲状腺功能减退.这些关联是否是巧合值得在未来的研究中研究。
