■有关心脏骤停(CA)影响的数据,心源性休克(CS),两者对中国ST段抬高型心肌梗死(STEMI)患者预后的影响有限。本研究旨在评估STEMI并发CA和CS的临床结局。并确定CA或CS的风险因素。
■本研究纳入了中国连续7468例STEMI患者。将患者分为4组(CA+CS,仅限CA,仅CS,且无CA或CS)。终点为30天全因死亡和主要不良心血管事件。进行Cox比例风险回归分析。
■CA,CS,它们的组合在332(4.4%)中被注意到,377(5.0%),所有患者中117例(1.6%)。在30天的随访中,817例(10.9%)全因死亡和964例(12.9%)主要不良心血管事件发生,和全因死亡率(3.6%,62.3%,74.1%,83.3%)和主要不良心血管事件(5.4%,67.1%,75.0%,和87.2%)在无CA或CS中显著增加,仅CS,仅限CA,和CA+CS组,分别。在多元Cox回归模型中,与无CA或CS组相比,CA+CS,CA,和仅CS组与全因死亡和主要不良心血管事件的风险增加相关.CA+CS患者的全因死亡风险最高(风险比[HR],25.259[95%置信区间(CI)19.221-33.195])和主要不良心血管事件(HR19.098,95CI14.797-24.648)。
■CA,CS,它们的组合在大约11%的中国STEMI患者中观察到,与中国STEMI患者30日死亡率和主要不良心血管事件风险增加相关.
UNASSIGNED: Data on the effect of cardiac arrest (CA), cardiogenic shock (CS), and their combination on the prognosis of Chinese patients with ST-segment elevation myocardial infarction (STEMI) are limited. The present
study sought to evaluate the clinical outcomes of STEMI complicated by CA and CS, and to identify the risk factors for CA or CS.
UNASSIGNED: This
study included 7468 consecutive patients with STEMI in China. The patients were divided into 4 groups (CA + CS, CA only, CS only, and No CA or CS). The endpoints were 30-day all-cause death and major adverse cardiovascular events. A Cox proportional hazards regression analysis was performed.
UNASSIGNED: CA, CS, and their combination were noted in 332 (4.4 %), 377 (5.0 %), and 117 (1.6 %) among all patients. During the 30-day follow-up, 817 (10.9 %) all-cause deaths and 964 (12.9 %) major adverse cardiovascular events occurred, and the incidence of all-cause mortality (3.6 %, 62.3 %, 74.1 %, 83.3 %) and major adverse cardiovascular events (5.4 %, 67.1 %, 75.0 %, and 87.2 %) significantly increased in the No CA or CS, CS only, CA only, and CA + CS groups, respectively. In the multivariate Cox regression models, compared with the No CA or CS group, the CA + CS, CA, and CS-only groups were associated with an increased risk of all-cause death and major adverse cardiovascular events. Patients with CA + CS had the highest risk of all-cause death (hazard ratio [HR], 25.259 [95 % confidence interval (CI) 19.221-33.195]) and major adverse cardiovascular events (HR 19.098, 95%CI 14.797-24.648).
UNASSIGNED: CA, CS, and their combination were observed in approximately 11 % of Chinese patients with STEMI, and were associated with increased risk for 30-day mortality and major adverse cardiovascular events in Chinese patients with STEMI.