Research synthesis

研究综合
  • 文章类型: Journal Article
    背景:医疗保健学生教育中经常隐藏的元素是公众参与的教学法,然而,公众参与可以为学生带来深度学习,对参与的公众产生积极影响。
    目的:本文旨在综合已发表的文献综述,描述公众参与对医护生教育的影响。
    方法:我们搜索了MEDLINE,EMBASE,ERIC,心理信息,CINAHL,PubMed,JBI系统评价和实施报告数据库,Cochrane系统评价数据库,效果评论摘要数据库和PROSPERO注册,用于公众参与医疗保健学生教育的文献评论。
    方法:包括过去10年发表的评论,如果他们描述了患者或公众参与医疗保健学生的教育,并报告了对学生的影响,公众,课程或医疗保健系统。
    方法:使用预先设计的数据提取表提取数据,并进行叙述合成。
    结果:20条评论符合我们的纳入标准,报告与学生有关的结果,公众,课程和未来的专业实践。
    结论:我们的发现提高了公众参与医疗保健学生教育的好处和挑战的认识,并可能为未来的研究提供信息,探索如何在高等教育中最好地利用公众参与。
    这项审查的灵感来自与公共医疗保健消费者的对话,他们看到了公众参与医疗保健学生教育的价值。研究包括公众参与者,更深入地了解公众参与对医疗保健学生教育的影响。
    BACKGROUND: An often-hidden element in healthcare students\' education is the pedagogy of public involvement, yet public participation can result in deep learning for students with positive impacts on the public who participate.
    OBJECTIVE: This article aimed to synthesize published literature reviews that described the impact of public participation in healthcare students\' education.
    METHODS: We searched MEDLINE, EMBASE, ERIC, PsychINFO, CINAHL, PubMed, JBI Database of Systematic Reviews and Implementation Reports, the Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects and the PROSPERO register for literature reviews on public participation in healthcare students\' education.
    METHODS: Reviews published in the last 10 years were included if they described patient or public participation in healthcare students\' education and reported the impacts on students, the public, curricula or healthcare systems.
    METHODS: Data were extracted using a predesigned data extraction form and narratively synthesized.
    RESULTS: Twenty reviews met our inclusion criteria reporting on outcomes related to students, the public, curriculum and future professional practice.
    CONCLUSIONS: Our findings raise awareness of the benefits and challenges of public participation in healthcare students\' education and may inform future research exploring how public participation can best be utilized in higher education.
    UNASSIGNED: This review was inspired by conversations with public healthcare consumers who saw value in public participation in healthcare students\' education. Studies included involved public participants, providing a deeper understanding of the impacts of public participation in healthcare students\' education.
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  • 文章类型: Journal Article
    了解人为压力源之间的相互作用对于有效保护和管理生态系统至关重要。淡水科学家已投入大量资源进行阶乘实验,以通过测试其个体和综合效应来解决压力源相互作用。然而,所研究的压力源和系统的多样性阻碍了该研究机构先前的综合。为了克服这一挑战,我们使用了一个新的机器学习框架,从超过235,000种出版物中确定了相关研究。我们的合成产生了一个新的数据集,该数据集包含2396个淡水系统中的多压力源实验。通过总结这些研究中使用的方法,量化所调查压力源的流行趋势,并进行共现分析,我们对迄今为止这一多样化的研究领域进行了最全面的概述。我们提供了将909调查的压力源分为31个类的分类法,以及数据集的开源和交互式版本(https://jamesaorr。shinyapps.io/淡水多重压力源/)。受到我们结果的启发,我们提供了一个框架来帮助澄清由阶乘实验检测到的统计相互作用是否与感兴趣的应激源相互作用一致,我们概述了与任何系统相关的多压力源实验设计的一般指南。最后,我们强调了更好地了解面临多种压力源的淡水生态系统所需的研究方向。
    Understanding the interactions among anthropogenic stressors is critical for effective conservation and management of ecosystems. Freshwater scientists have invested considerable resources in conducting factorial experiments to disentangle stressor interactions by testing their individual and combined effects. However, the diversity of stressors and systems studied has hindered previous syntheses of this body of research. To overcome this challenge, we used a novel machine learning framework to identify relevant studies from over 235,000 publications. Our synthesis resulted in a new dataset of 2396 multiple-stressor experiments in freshwater systems. By summarizing the methods used in these studies, quantifying trends in the popularity of the investigated stressors, and performing co-occurrence analysis, we produce the most comprehensive overview of this diverse field of research to date. We provide both a taxonomy grouping the 909 investigated stressors into 31 classes and an open-source and interactive version of the dataset (https://jamesaorr.shinyapps.io/freshwater-multiple-stressors/). Inspired by our results, we provide a framework to help clarify whether statistical interactions detected by factorial experiments align with stressor interactions of interest, and we outline general guidelines for the design of multiple-stressor experiments relevant to any system. We conclude by highlighting the research directions required to better understand freshwater ecosystems facing multiple stressors.
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  • 文章类型: Systematic Review
    背景:恢复策略用于提高运动员的表现并降低受伤风险。在以前的系统综述中,研究了个人康复策略,以阐明其对混合组运动员的有效性。然而,目前的证据含糊不清,并且仍然缺乏对耐力运动员(训练)恢复的清晰概述。
    方法:我们根据PubMed的文献检索进行了综述,Cochrane系统评价数据库,和WebofScience。包括在2022年12月之前以英文发布的评论。如果在耐力运动员的训练后,与安慰剂或对照组相比,系统评价和荟萃分析调查了一种或多种恢复策略的有效性,则符合资格。
    结果:22篇综述(9篇系统综述,三个荟萃分析,和包含荟萃分析的十篇系统综述)符合纳入标准。总的来说,我们对1100名耐力运动员的63项研究纳入了我们的综述。在63项研究中,8提供了有关数据合成的训练恢复时间框架的信息。其中,冷冻疗法和压缩服装显示出积极的效果,而应用按摩没有效果。总的来说,纳入的恢复策略均未显示对耐力运动员的持续获益.
    结论:没有特别的恢复策略可以建议在耐力运动员的训练或比赛之间提高恢复。然而,个别研究表明,压缩服装和冷冻疗法是有效的训练恢复策略。进一步的研究应改进方法,并侧重于恢复过程的不同时间过程。
    背景:审查方案已在国际前瞻性系统审查注册中心注册,编号为CRD42021260509。
    BACKGROUND: Recovery strategies are used to enhance performance and reduce injury risk in athletes. In previous systematic reviews, individual recovery strategies were investigated to clarify their effectiveness for mixed groups of athletes. However, the current evidence is ambiguous, and a clear overview of (training) recovery for endurance athletes is still lacking.
    METHODS: We conducted an umbrella review based on a literature search in PubMed, Cochrane Database of Systematic Reviews, and Web of Science. Reviews published in English and before December 2022 were included. Systematic reviews and meta-analyses were eligible if they investigated the effectiveness of one or more recovery strategies compared with a placebo or control group after a training session in endurance athletes.
    RESULTS: Twenty-two reviews (nine systematic reviews, three meta-analyses, and ten systematic reviews with meta-analyses included) met the inclusion criteria. In total, sixty-three studies with 1100 endurance athletes were included in our umbrella review. Out of the sixty-three studies, eight provided information on training recovery time frame for data synthesis. Among them, cryotherapy and compression garments showed positive effects, while applying massage showed no effect. In general, none of the included recovery strategies showed consistent benefits for endurance athletes.
    CONCLUSIONS: There is no particular recovery strategy that can be advised to enhance recovery between training sessions or competitions in endurance athletes. However, individual studies suggest that compression garments and cryotherapy are effective training recovery strategies. Further research should improve methodology and focus on the different time courses of the recovery process.
    BACKGROUND: The review protocol was registered with the International Prospective Register of Systematic Reviews with the number CRD42021260509.
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  • 文章类型: Systematic Review
    同伴调解干预(PMI)已被牢固地确立为基于证据的方法,以促进有残疾和无残疾学生之间的同伴关系。我们对评估PMI研究的综述进行了回顾,以支持儿童的社交技能和积极的行为结果,青少年,以及患有智力和发育障碍(IDD)的年轻人。在43条文献综述中,共有4,254名患有IDD的个体是参与者,反映了357项独特的研究。本审查包括与参与者人口统计信息相关的编码,干预特点,实现保真度,社会有效性,以及PMI跨评论解决的社会成果。我们的研究结果表明,PMI对患有IDD的个体产生积极的社会和行为结果,主要是在同伴参与和发起社交互动领域。具体技能,运动行为,挑战性和亲社会行为不太可能在整个研究中进行检查。将讨论支持实施PMI的研究和实践的含义。
    Peer-mediated interventions (PMIs) have been firmly established as evidence-based approaches for facilitating peer relationships among students with and without disabilities. We conducted a review of reviews evaluating PMI studies to support social skills and positive behavioral outcomes for children, adolescents, and young adults with intellectual and developmental disabilities (IDD). A total of 4,254 individuals with IDD were participants across 43 reviews of the literature, reflecting 357 unique studies. This review includes coding related to participant demographic information, intervention characteristics, implementation fidelity, social validity, and social outcomes addressed by PMIs across reviews. Our findings suggest that PMIs yield positive social and behavioral outcomes for individuals with IDD, mostly in the areas of peer engagement and initiating social interactions. Specific skills, motor behaviors, and challenging as well as prosocial behaviors were less likely to be examined across studies. Implications for research and practice to support the implementation of PMIs will be discussed.
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  • 文章类型: Systematic Review
    It is unclear whether virtual reality (VR)-based exercise can improve physical fitness in people with intellectual disability (ID). This systematic review therefore aimed to synthesize existing evidence regarding the efficacy of VR-based exercise on physical fitness in people with ID. Eligible articles were searched through six major electronic databases from inception until August 15, 2022. Returned studies were screened through predefined inclusion and exclusion criteria. Data from the included studies were then extracted and synthesized. A total of 13 randomized controlled trials were included and 12 of them were found to have good research quality. Different physical fitness outcomes were evaluated: (1) muscular fitness (d = 0.05-2.12; proportion of effect = 5/6), (2) cardiorespiratory fitness (d = 0.12-0.67; proportion of effect = 5/5), (3) flexibility (d = 0.81; proportion of effect = 1/2), (4) body composition (d = 0.10; proportion of effect = 2/3), (5) balance (d = 0.23-1.65; proportion of effect = 6/7), (6) coordination (d = 0.19-0.48; proportion of effect = 2/3), (7) speed and agility (d = 0.13-0.46; proportion of effect = 4/4), and (8) overall motor proficiency (d = 0.02-1.08; proportion of effect = 1/3). While there was some preliminary evidence showing that VR-based exercise could improve muscular fitness, cardiorespiratory fitness, balance, and speed and agility in individuals with ID, other outcomes showed less conclusive or limited positive evidence. Overall, additional studies are needed to understand the benefits of VR-based exercise on physical fitness in people with ID.
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  • 文章类型: Systematic Review
    Task-based functional magnetic resonance imaging (tfMRI) has developed as a common alternative in epilepsy surgery to the intracarotid amobarbital procedure, also known as the Wada procedure. Prior studies have implicated tfMRI as a comparable predictor of postsurgical cognitive outcomes. However, the predictive validity of tfMRI has not been established. This preregistered systematic review and meta-analysis (CRD42020183563) synthesizes the literature predicting postsurgical cognitive outcomes in temporal lobe epilepsy (TLE) using tfMRI. The PubMed and PsycINFO literature databases were queried for English-language articles published between January 1, 2009 and December 31, 2020 associating tfMRI laterality indices or symmetry of task activation with outcomes in TLE. Their references were reviewed for additional relevant literature, and unpublished data from our center were incorporated. Nineteen studies were included in the meta-analysis. tfMRI studies predicted postsurgical cognitive outcomes in left TLE ( ρ ̂ = -.27, 95% confidence interval [CI] = -.32 to -.23) but not right TLE ( ρ ̂ = -.02, 95% CI = -.08 to .03). Among studies of left TLE, language tfMRI studies were more robustly predictive of postsurgical cognitive outcomes ( ρ ̂ = -.27, 95% CI = -.33 to -.20) than memory tfMRI studies ( ρ ̂ = -.27, 95% CI = -.43 to -.11). Further moderation by cognitive outcome domain indicated language tfMRI predicted confrontation naming ( ρ ̂ = -.32, 95% CI = -.41 to -.22) and verbal memory ( ρ ̂ = -.26, 95% CI = -.35 to -.17) outcomes, whereas memory tfMRI forecasted only verbal memory outcomes ( ρ ̂ = -.37, 95% CI = -.57 to -.18). Surgery type, birth sex, level of education, age at onset, disease duration, and hemispheric language dominance moderated study outcomes. Sensitivity analyses suggested the interval of postsurgical follow-up, and reporting and methodological practices influenced study outcomes as well. These findings intimate tfMRI is a modest predictor of outcomes in left TLE that should be considered in the context of a larger surgical workup.
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  • 文章类型: Journal Article
    1型神经纤维瘤病(NF1)是一种常见的遗传性疾病,通常与认知缺陷有关。尽管认知缺陷是NF1的关键特征,但NF1中此类损伤的特征已被证明是异质的。因此,我们试图定量综合现有的关于NF1认知功能的文献。对横断面研究进行了随机效应荟萃分析,将NF1患者的认知功能与所有年龄段的典型发育或未受影响的同胞比较对象进行了比较。分析包括50篇文章(总NNF1=1,522;MAge=15.70年,范围=0.52-69.60),产生460个效果大小。观察到总体中度缺陷[g=-0.64,95%CI=(-0.69,-0.60)],其中损伤在认知域水平上不同。缺陷范围从大[一般智力:g=-0.95,95%CI=(-1.12,-0.79)]到小[情绪:g=-0.37,95%CI=(-0.63,-0.11)]。适度分析显示年龄的贡献不显著,性别,教育程度,和父母的教育水平对结果的影响。这些结果表明,在NF1的整个生命周期中,认知障碍是分散和突出的。一起来看,这些结果进一步表明,应结合现有的最佳实践来评估和解决NF1患者的认知发病率.
    Neurofibromatosis Type 1 (NF1) is a common genetic disorder frequently associated with cognitive deficits. Despite cognitive deficits being a key feature of NF1, the profile of such impairments in NF1 has been shown to be heterogeneous. Thus, we sought to quantitatively synthesize the extant literature on cognitive functioning in NF1. A random-effects meta-analysis of cross-sectional studies was carried out comparing cognitive functioning of patients with NF1 to typically developing or unaffected sibling comparison subjects of all ages. Analyses included 50 articles (Total NNF1 = 1,522; MAge = 15.70 years, range = 0.52-69.60), yielding 460 effect sizes. Overall moderate deficits were observed [g = -0.64, 95% CI = (-0.69, -0.60)] wherein impairments differed at the level of cognitive domain. Deficits ranged from large [general intelligence: g = -0.95, 95% CI = (-1.12, -0.79)] to small [emotion: g = -0.37, 95% CI = (-0.63, -0.11)]. Moderation analyses revealed nonsignificant contributions of age, sex, educational attainment, and parental level of education to outcomes. These results illustrate that cognitive impairments are diffuse and salient across the lifespan in NF1. Taken together, these results further demonstrate efforts should be made to evaluate and address cognitive morbidity in patients with NF1 in conjunction with existing best practices.
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  • 文章类型: Journal Article
    在致命和伤害机动车碰撞中经常检测到大麻和酒精。虽然对大麻和酒精的流行病学荟萃分析发现与撞车风险增加有关,来自驾驶绩效测量的汇聚证据在数量上没有充分表征。我们的目标是量化大麻和酒精对驾驶表现和行为的影响程度。
    系统评价和荟萃分析。我们系统地搜索了完整的学术搜索,CINAHL,Embase,Scopus,谷歌学者,MEDLINE,PsycINFO,SPORTDiscusandTRID.在进行全文回顾的616项研究中,本荟萃分析包含57项研究和1725名参与者.我们提取了危险响应时间的数据,横向位置变异性,车道偏离或短途旅行,离开车道的时间,行驶速度,行驶速度变异性,速度违规,时间超速行驶,进展,来自实验驾驶研究的前进速度变异性和碰撞(即驾驶模拟器,闭路,路上)涉及大麻和/或酒精管理。我们报告了使用Hedges\'g和r的效应大小的荟萃分析。
    单独使用大麻与横向控制受损相关[例如,对于横向位置变异性,g=0.331,95%置信区间(CI)=0.212-0.451;对于车道偏移,g=0.198,95%CI=0.001-0.395)和行驶速度降低(g=-0.176,95%CI=-0.298至-0.053与单独使用的任何一种药物相比,大麻和酒精的组合与更大的驾驶性能下降相关[例如,对于横向位置变异性(组合与酒精),g=0.480,95%CI=0.096-0.865;g=0.525,95%CI=0.049-1.002对于车道外时间(与酒精);g=0.336,95%CI=0.036-0.636对于横向位置变异性(组合与];g=0.亚组分析表明,大麻对驾驶绩效指标的影响类似于低血液酒精浓度。数据的匮乏和研究的异质性限制了对某些措施的解释。
    这项荟萃分析表明,大麻,像酒精一样,损害驾驶,两种药物的组合比单独使用时更不利于驾驶性能。
    Cannabis and alcohol are frequently detected in fatal and injury motor vehicle crashes. While epidemiological meta-analyses of cannabis and alcohol have found associations with an increase in crash risk, convergent evidence from driving performance measures is insufficiently quantitatively characterized. Our objectives were to quantify the magnitude of the effect of cannabis and alcohol-alone and in combination-on driving performance and behaviour.
    Systematic review and meta-analysis. We systematically searched Academic Search Complete, CINAHL, Embase, Scopus, Google Scholar, MEDLINE, PsycINFO, SPORTDiscus and TRID. Of the 616 studies that underwent full-text review, this meta-analysis represents 57 studies and 1725 participants. We extracted data for hazard response time, lateral position variability, lane deviations or excursions, time out of lane, driving speed, driving speed variability, speed violations, time speeding, headway, headway variability and crashes from experimental driving studies (i.e. driving simulator, closed-course, on-road) involving cannabis and/or alcohol administration. We reported meta-analyses of effect sizes using Hedges\' g and r.
    Cannabis alone was associated with impaired lateral control [e.g. g = 0.331, 95% confidence interval (CI) = 0.212-0.451 for lateral position variability; g = 0.198, 95% CI = 0.001-0.395 for lane excursions) and decreased driving speed (g = -0.176, 95% CI = -0.298 to -0.053]. The combination of cannabis and alcohol was associated with greater driving performance decrements than either drug in isolation [e.g. g = 0.480, 95% CI = 0.096-0.865 for lateral position variability (combination versus alcohol); g = 0.525, 95% CI = 0.049-1.002 for time out of lane (versus alcohol); g = 0.336, 95% CI = 0.036-0.636 for lateral position variability (combination versus cannabis; g = 0.475, 95% CI = 0.002-0.949 for time out of lane (combination versus cannabis)]. Subgroup analyses indicated that the effects of cannabis on driving performance measures were similar to low blood alcohol concentrations. A scarcity of data and study heterogeneity limited the interpretation of some measures.
    This meta-analysis indicates that cannabis, like alcohol, impairs driving, and the combination of the two drugs is more detrimental to driving performance than either in isolation.
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  • 文章类型: Journal Article
    Road crashes are preventable causes of morbidity and mortality. In the U.S., substantial crashes occur during the rush hour period. The rush hour represents the period of the day during which the density of humans and vehicles in the road environment is highest. In the U.S., the rush hour period is bi-modal, occurring in the morning and the afternoon, at times that vary by state and urban-rural status. This systematic review and meta-analysis aimed to evaluate the association between the rush hour period and fatal and non-fatal crash injuries. Selected articles were limited to peer-reviewed full-text articles that measured crash injury as an outcome and rush hour as either a predictor, covariate, stratification, or a control variable. A total of 17 articles were identified for systematic review and nine articles were included in the meta-analysis. Across the selected studies, the rush-hour period signified the period of \"peak traffic flow.\" During the rush hour period, aggressive driving behavior, truck driving, bicycle riding, and precipitation were associated with increased crash events or crash injuries. Across the nine studies included in the meta-analysis, the effective sample size was 236,433. The rush-hour period was associated with a 28% increased risk of fatal crash injury (Pooled RR: 1.28; 95% CI: 1.11-1.45) and the morning rush hour period was associated with 36% increased crash injury risk (Pooled RR: 1.36; 95% CI: 1.13-1.59). The rush hour period, though less commonly studied as a predictor of fatal and non-fatal crash injuries, represents an important domain in need of crash injury prevention attention. The knowledge of the pattern of crash injuries, as it varies across countries, states, regions, and county can inform policy and intervention, in the presence of competing public health needs.
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  • 文章类型: Journal Article
    BACKGROUND: Information on sexual and reproductive health is increasingly disseminated via social media and reaches a large audience.
    OBJECTIVE: Against this background, the aim of this paper is to systematically summarize the international state of research on sexual health information on social media for the first time with a scoping review. Seven research questions were explored, relating to the amount (F1), methods (F2: content analysis, F3: quality analysis), and results (F4: providers, F5: target groups, F6: topics, F7: quality of information) of previous studies.
    METHODS: The study follows the PRISMA framework for scoping reviews as well as the Open Science approach. It is preregistered, and all materials (codebook with reliability coefficients) and data (list of identified studies and coding of studies) are available on the Open Science Foundation server.
    RESULTS: A total of 69 studies with 72 data sets were identified, with more than half of the publications referring to YouTube (F1). Qualitative and quantitative methods of content analysis are used equally (F2) and quality analyses are rare (F3). Health laypersons dominate as the information providers (F4). The target groups are mostly unspecified (F5). The health information on social media examined in the previous studies covers a broad range of topics (F6). Where quality assessments were made, they tended to be negative (F7).
    CONCLUSIONS: More research is needed to better understand sexual and reproductive health information on social media and to promote its quality and constructive use.
    UNASSIGNED: HINTERGRUND: Informationen zur sexuellen und reproduktiven Gesundheit werden zunehmend auch über soziale Medien verbreitet und erreichen dort ein großes Publikum.
    UNASSIGNED: Vor diesem Hintergrund ist es Ziel des vorliegenden Beitrags, den internationalen Forschungsstand zu sexuellen Gesundheitsinformationen in sozialen Medien erstmals systematisch mit einem Scoping Review aufzuarbeiten. Es sollen 7 Forschungsfragen beantwortet werden, die sich auf den Umfang (F1), die Methoden (F2: Inhaltsanalyse, F3: Qualitätsanalyse) sowie die Ergebnisse (F4: Anbieter, F5: Zielgruppen, F6: Themen, F7: Qualität der Informationen) bisheriger Studien beziehen.
    METHODS: Die Untersuchung folgt dem PRISMA-Framework für Scoping Reviews sowie dem Open-Science-Ansatz: Sie ist präregistriert und alle Materialien (Codebuch mit Reliabilitätskoeffizienten) und Daten (Liste der identifizierten Studien, Codierung der Studien) stehen auf dem Server der Open Science Foundation zur Verfügung.
    UNASSIGNED: Es konnten insgesamt 69 Studien mit 72 Datensätzen identifiziert werden, wobei sich mehr als die Hälfte der Publikationen auf YouTube bezieht (F1). Qualitative und quantitative Methoden der Inhaltsanalyse kommen gleichermaßen zum Einsatz (F2), Qualitätsanalysen sind rar (F3). Bei den Anbietern dominieren Gesundheitslaien (F4). Die Zielgruppen sind meist unspezifiziert (F5). Die in den vorliegenden Studien untersuchten Gesundheitsinformationen in sozialen Medien behandeln ein breites Themenspektrum (F6). Sofern Qualitätseinschätzungen vorgenommen wurden, fielen diese eher negativ aus (F7).
    CONCLUSIONS: Mehr Forschung ist notwendig, um sexuelle und reproduktive Gesundheitsinformationen in sozialen Medien besser zu verstehen und um ihre Qualität und konstruktive Nutzung zu fördern.
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