Psychiatric

精神病
  • 文章类型: Journal Article
    目标:生活在农村和偏远地区的年轻澳大利亚人的心理健康结果较差,自残和自杀率高于主要城市的同龄人。在获得一般和针对青年的心理健康服务方面存在巨大的服务差距和障碍。由于缺乏访问权限,随之而来的是治疗延误和相关较差的结果。本文介绍了需要进行航空医学检索(AR)以进行急性住院精神病治疗的年轻人的特征。
    方法:对2016年至2021年6年的皇家飞行医生服务AR进行了回顾性二次分析。数据按人口统计汇总,地理,和诊断因素。
    结果:总样本量为1534(60%的男性,40%为女性;31%为12-17岁,69%年龄在18-24岁之间),668(43.5%)受精神分裂症和相关疾病的影响。奥古斯塔港,阿德莱德以北300公里,航空医疗取回的比例最高(4.4%)。阿德莱德的妇女和儿童医院接受的取回比例最高(25.6%)。在澳大利亚几个州的特定高使用率地理位置中,性别和年龄差异具有统计学意义。
    结论:AR对于年轻人获得专科急性卫生服务至关重要。适当的发展,响应,青少年心理健康服务大多位于大型,已经资源充足的主要城市。我们的研究提供了有价值的信息来帮助政府,社区,和服务,以增加为生活在农村的年轻人提供的资源。
    OBJECTIVE: Young Australians living in rural and remote locations have poorer mental health outcomes and higher rates of self-harm and suicide than their major city counterparts. Significant service gaps and barriers exist in accessing general and youth-specific mental health services. With a lack of access, comes delays in treatment and associated poorer outcomes. This paper describes the characteristics of young people requiring an aeromedical retrieval (AR) for acute inpatient psychiatric care.
    METHODS: A retrospective secondary analysis was conducted of Royal Flying Doctor Service ARs for a six-year period from 2016 to 2021. Data were summarised by demographic, geographic, and diagnostic factors.
    RESULTS: The total sample size was 1534 (60% male, 40% female; and 31% aged 12-17 years, 69% aged 18-24 years), with 668 (43.5%) affected by schizophrenia and related disorders. Port Augusta, 300 km north of Adelaide, had the highest proportion of aeromedical retrievals (4.4%). The Women\'s and Children\'s Hospital in Adelaide received the highest proportion of retrievals (25.6%). Statistically significant gender and age differences were identified as were specific high-usage geographical locations across several Australian states.
    CONCLUSIONS: AR is essential for young people in accessing specialist acute health services. Developmentally appropriate, responsive, youth mental health services are mostly located in large, already well-resourced major cities. Our study provides valuable information to assist governments, communities, and services to enhance the resources available for young people who live rurally.
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  • 文章类型: Case Reports
    我们在一名31岁的女性患者中出现了异常的抗磷脂综合征(APS)病例,表现出神经精神表现,随后是血栓栓塞性卒中。APS的特征在于抗磷脂抗体导致血栓前状态和血栓形成事件的风险增加。虽然APS的神经系统受累通常表现为血栓形成事件,抗磷脂抗体也可能直接与神经组织相互作用,引起立即的致病作用,破坏正常功能。APS的神经精神表现很少见,但以前已经有记录,包括精神病和幻觉.在有神经精神症状的患者中及时识别APS对于适当的管理和预防进一步的并发症至关重要。报告的患者表现出攻击性,离奇,进入精神科后的行为不稳定,其次是右侧面部下垂和无力的发展。影像学检查显示左大脑中动脉(MCA)狭窄和部分闭塞,重复扫描显示已知的左MCA区梗死,特定脑区的低密度增加。值得注意的是,患者在双侧上肢表现出多发性紫癜性瘀斑,怀疑高凝状态。实验室调查检测到抗心磷脂IgG和β-2糖蛋白1IgG水平升高,以及抗核抗体阳性.通过超声心动图也证实了卵圆孔未闭的存在。这个案例强调了在有神经精神症状的患者中早期识别APS的重要性,促进适当的干预和改善的结果。进一步的研究是必要的,以阐明潜在的病理生理机制连接APS的神经精神表现,能够加强对这一复杂状况的理解和精细化管理。
    We present an unusual case of antiphospholipid syndrome (APS) in a 31-year-old female patient exhibiting neuropsychiatric manifestations, followed by a subsequent thromboembolic stroke. APS is characterized by antiphospholipid antibodies leading to a prothrombotic state and an increased risk of thrombotic events. While the neurological involvement in APS typically presents with thrombotic events, antiphospholipid antibodies may also directly interact with neural tissue, causing immediate pathogenic effects that disrupt normal function. Neuropsychiatric manifestations in APS are rare but have been documented previously, including cases of psychosis and hallucinations. The timely recognition of APS in patients with neuropsychiatric symptoms is crucial for appropriate management and the prevention of further complications. The reported patient displayed aggressive, bizarre, and erratic behavior upon admission to the psychiatric unit, followed by the development of right-sided facial droop and weakness. Imaging studies revealed stenosis and partial occlusion of the left middle cerebral artery (MCA), and a repeat scan showed a known left MCA territory infarct with increasing hypodensity in specific brain regions. Notably, the patient exhibited multiple purpuric ecchymoses on bilateral upper extremities, raising suspicion of a hypercoagulable state. Laboratory investigations detected elevated levels of anticardiolipin IgG and beta-2 glycoprotein 1 IgG, along with a positive antinuclear antibody. The presence of a patent foramen ovale was also confirmed through echocardiography. This case emphasizes the importance of early APS recognition in patients with neuropsychiatric symptoms, facilitating appropriate intervention and improved outcomes. Further research is warranted to elucidate the underlying pathophysiological mechanisms connecting APS to neuropsychiatric manifestations, enabling enhanced understanding and refined management of this intricate condition.
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  • 文章类型: Journal Article
    人们越来越意识到COVID-19大流行对许多美国人的心理健康影响。关于在大流行发作之前对患有精神健康状况的个体的影响知之甚少。此外,很少有研究探讨这一群体如何积极应对COVID-19的挑战。了解这些人对大流行的需求和干扰带来的优势,可以为这些人在这次公共卫生紧急情况后的康复提供信息。使用横截面的结果,在2020年4月和5月进行的在线调查中,我们使用定性方法来检查有抑郁和焦虑症状的个体如何应对COVID-19。参与者是从新泽西州和纽约州的两个全州行为健康社区计划网络中招募的。数据来自48名参与者,他们报告了通过广义焦虑症2量表评估的焦虑症状和/或通过患者健康问卷2评估的抑郁。这些受访者在应对COVID-19带来的干扰方面表现出了韧性,并报告了一系列健康的应对策略。我们确定了成功应对策略的三个主题,包括利用社会支持系统,练习自我照顾,并调整自己的心态来应对具有挑战性的经历。在设计程序时,政策,以及支持有精神健康状况的人的临床方法,必须注重优势。在这项研究中,个人分享的应对策略证明并建立在他们的韧性上。需要更多的研究来发现人们在应对COVID-19大流行带来的挑战方面表现出的优势。
    There is growing awareness of the significant mental health impacts of the COVID-19 pandemic on many Americans. Less is known about the effects on individuals who were living with mental health conditions prior to the pandemic\'s onset. In addition, little research has explored how this group is coping positively with the challenges of COVID-19. Understanding the strengths these individuals bring to pandemic demands and disruptions can inform recovery for these individuals in the aftermath of this public health emergency. Using results from a cross-sectional, online survey administered during April and May 2020, we use qualitative methods to examine how individuals with symptoms of depression and anxiety were coping with COVID-19. Participants were recruited from two networks of statewide behavioral health community programs in New Jersey and New York. Data come from 48 participants who reported current symptoms of anxiety assessed by the Generalized Anxiety Disorder-2 Scale and/or depression assessed by the Patient Health Questionnaire-2. These respondents demonstrated resilience in navigating disruptions brought on by COVID-19 and reported a range of healthy coping strategies. We identified three themes characterizing successful coping strategies, including utilizing social support systems, practicing self-care, and adjusting one\'s mindset to deal with challenging experiences. When designing programs, policies, and clinical approaches to support people with mental health conditions, it is essential to focus on strengths. The coping strategies shared by the individuals in this study demonstrate and build on their resilience. More research is needed to discover the strengths people exhibit to deal with the challenges caused by the COVID-19 pandemic.
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  • 文章类型: Journal Article
    背景:心理健康问题和自杀观念在青少年中很常见。从长远来看,早期发现这些问题可以防止与心理健康相关的症状升级。此外,结合情绪调节策略来表征流行症状的不同特征可以指导具体干预措施的设计。使用基于网络的筛查(WBS)工具已被视为一种合适的策略,以及时发现症状,同时提高吸引力,成本,及时性、及时性以及在年轻人群中的检测范围。然而,关于这些方法准确性的证据并不完全是决定性的。
    目的:本研究的目的是(1)研究WBS识别有精神症状和自杀倾向的青少年的能力,以及(2)使用WBS对大量青少年的心理健康特征进行表征。
    方法:总共1599名讲西班牙语的拉丁美洲青少年(平均年龄15.56,SD1.34岁),由47.3%(n=753)女性组成,98.5%智利(n=1570),和1.5%的委内瑞拉(n=24)参与者,回应心理健康WBS。参与者的随机子样本也回答了迷你国际儿童和青少年神经精神病学访谈(MINI-KID)。McNemarχ2和接收器工作特性曲线测试了WBS与MINI-KID的检测精度。潜在概况分析探讨了参与者的症状和情绪调节概况。
    结果:两种测量都显示出足够的一致性(每个症状域的曲线下面积范围为0.70至0.89);但是,WBS在所有精神症状中的患病率均高于MINI-KID,除了自杀意念和抑郁.潜在轮廓分析产生了4个轮廓-其中一个表现出升高的精神病理症状,占样本的11%(n=175)。反省(比值比[OR]130.15,95%CI51.75-439.89;P<.001),截留(OR96.35,95%CI29.21-317.79;P<.001),失败(OR156.79,95%CI50.45-487.23;P<.001)对潜在档案成员的预测做出了显著贡献,虽然认知重估并没有有助于预测任何潜在的个人资料成员,表达抑制仅与配置文件-2成员资格相关。
    结论:WBS对于及时发现有精神健康状况风险的青少年是可以接受的。症状和情绪调节概况的发现强调了全面评估和差异干预措施的必要性。
    BACKGROUND: Mental health problems and suicide ideation are common in adolescents. Early detection of these issues could prevent the escalation of mental health-related symptoms in the long term. Moreover, characterizing different profiles of prevalent symptoms in conjunction with emotional regulation strategies could guide the design of specific interventions. The use of web-based screening (WBS) tools has been regarded as a suitable strategy to timely detect symptomatology while improving the appeal, cost, timeliness, and reach of detection in young populations. However, the evidence regarding the accuracy of these approaches is not fully conclusive.
    OBJECTIVE: The study aims (1) to examine the capability of a WBS to identify adolescents with psychiatric symptoms and suicidality and (2) to characterize the mental health profiles of a large sample of adolescents using WBS.
    METHODS: A total of 1599 Latin American Spanish-speaking adolescents (mean age 15.56, SD 1.34 years), consisting of 47.3% (n=753) female, 98.5% Chilean (n=1570), and 1.5% Venezuelan (n=24) participants, responded to a mental health WBS. A randomized subsample of participants also responded to the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID). McNemar χ2 and receiver-operating characteristic curves tested the detection accuracy of WBS contrasted with the MINI-KID. Latent profile analyses explored the symptomatic and emotional regulation profiles of participants.
    RESULTS: Both measures showed an adequate level of agreement (area under the curve per symptom domain ranging from 0.70 to 0.89); however, WBS yielded a higher prevalence than MINI-KID for all psychiatric symptoms, except suicide ideation and depression. Latent profile analyses yielded 4 profiles-one of them presented elevated psychopathological symptoms, constituting 11% of the sample (n=175). Rumination (odds ratio [OR] 130.15, 95% CI 51.75-439.89; P<.001), entrapment (OR 96.35, 95% CI 29.21-317.79; P<.001), and defeat (OR 156.79, 95% CI 50.45-487.23; P<.001) contributed significantly to the prediction of latent profile memberships, while cognitive reappraisal did not contribute to the prediction of any latent profile memberships, and expressive suppression was only associated to profile-2 membership.
    CONCLUSIONS: WBS is acceptable for the timely detection of adolescents at risk of mental health conditions. Findings from the symptomatic and emotional regulation profiles highlight the need for comprehensive assessments and differential interventions.
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  • 文章类型: Journal Article
    背景:在美国,与甲基苯丙胺相关的过量死亡和药物治疗入院人数正在上升。这项研究旨在测量和比较美国与甲基苯丙胺有关的精神病住院的时间趋势。
    方法:我们以人群为基础,美国精神病住院率的趋势分析,并计算出每100,000名涉及物质的精神病住院患者的季度(Q)率.我们使用Joinpoint回归评估了美国地区季度住院率百分比变化。
    结果:从2015年第四季度到2019年第四季度,有963,202例精神病住院,50,223(5.2%)涉及甲基苯丙胺,102,877(10.7%)涉及阿片类药物和/或可卡因,不含甲基苯丙胺。涉及甲基苯丙胺的精神病住院率增加了68.0%,涉及阿片类药物和/或可卡因而不含甲基苯丙胺的精神病住院率下降了22%,而非物质相关的精神病住院率保持不变。与甲基苯丙胺有关的精神病住院率的最大显着增加是在61岁以上的人群中,男性,和中西部人。在黑人患者中,涉及甲基苯丙胺的精神病住院率翻了一番。在中西部地区,与甲基苯丙胺有关的精神病住院治疗的平均增幅最大,为2015年第四季度至2017年第二季度的10.2%。
    结论:大多数精神病住院不涉及药物。涉及甲基苯丙胺的精神病住院治疗大大增加,而涉及阿片类药物的精神病住院治疗减少,但涉及更多的接触。获得更多减少伤害服务的机会,应急管理计划,迫切需要精神卫生服务。
    BACKGROUND: In the U.S., overdose deaths and substance treatment admissions related to methamphetamine are rising. This study aims to measure and compare U.S. temporal trends in methamphetamine-involved psychiatric hospitalizations.
    METHODS: We conducted a population-based, trend analysis of U.S. psychiatric hospitalizations and calculated quarterly (Q) rates per 100,000 population of substance-involved psychiatric hospitalizations. We assessed U.S. regional quarterly percentage hospitalization rate changes using Joinpoint regression.
    RESULTS: From Q4 2015-Q4 2019, there were 963,202 psychiatric hospitalizations, 50,223 (5.2 %) involved methamphetamine and 102,877 (10.7 %) involved opioids and/or cocaine without methamphetamine. Methamphetamine-involved psychiatric hospitalization rates increased by 68.0 %, psychiatric hospitalizations rates involving opioid and/or cocaine without methamphetamine decreased by 22 %, while nonsubstance-involved psychiatric hospitalizations rates remained unchanged. The largest significant increases in methamphetamine-involved psychiatric hospitalization rates were among people >61 years old, males, and Midwesterners. Methamphetamine-involved psychiatric hospitalization rates doubled among Black patients. The largest average percent increase among methamphetamine-involved psychiatric hospitalizations was 10.2 % from Q4 2015-Q2 2017 in the Midwest.
    CONCLUSIONS: Most psychiatric hospitalizations did not involve substances. Methamphetamine-involved psychiatric hospitalizations greatly increased while opioid-involved psychiatric hospitalizations decreased, but involved more total encounters. Greater access to harm reduction services, contingency management programs, and mental health services is urgently needed.
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  • 文章类型: Journal Article
    背景技术牛皮癣是一种主要影响皮肤的慢性炎症性疾病,并且可以显著影响生活质量。以前的研究表明,牛皮癣会增加患抑郁症的风险;然而,在沙特阿拉伯,缺乏有关抑郁症和银屑病患者接受转诊至精神病诊所的患病率的信息。这项研究旨在评估沙特阿拉伯银屑病患者中抑郁症的患病率,确定他们转诊到精神病诊所的接受率,并评估他们对抑郁症状对牛皮癣的影响的知识。方法这项基于问卷调查的横断面研究包括沙特阿拉伯皮肤科诊所就诊的银屑病患者。所有患者都被指示完成三组包含社会人口统计信息的问卷,他们疾病的临床特征,还有贝克抑郁量表.结果406例患者中,54.9%有抑郁症状,当出现抑郁症状时,46.3%的人愿意去看精神科医生。大多数患者(70%)认为抑郁症会影响牛皮癣。结论本研究中超过一半的银屑病患者患有抑郁症。患者了解抑郁症会导致症状恶化,但大多数人拒绝看精神病医生.为了消除看精神病医生的障碍,牛皮癣患者应提供心理健康援助,学会识别心理压力源和应对这些压力源的有效策略,并接受了有关可用服务的教育,包括远程医疗。
    Background Psoriasis is a chronic inflammatory disease that primarily affects the skin and can significantly impact the quality of life. Previous studies have shown that psoriasis increases the risk of depression; however, there is a lack of information about the prevalence of depression and psoriatic patients\' acceptance of referral to a psychiatric clinic in Saudi Arabia. This study aims to estimate the prevalence of depression among psoriatic patients in Saudi Arabia, determine their referral acceptance rate to psychiatric clinics, and assess their knowledge regarding the impact of depressive symptoms on psoriasis. Methods This questionnaire-based cross-sectional study included patients with psoriasis who presented to dermatology clinics in Saudi Arabia. All patients were instructed to complete three sets of questionnaires encompassing sociodemographic information, the clinical characteristics of their illness, and the Beck Depression Inventory. Results Of 406 patients, 54.9% had symptoms of depression, and 46.3% were willing to go to a psychiatrist when symptoms of depression were present. Most of the patients (70%) thought that depression affects psoriasis. Conclusions More than half of the psoriatic patients in this study were depressed. The patients understood that depression can lead to a worsening of their symptoms, but the majority refused to see a psychiatrist. To remove barriers to seeing a psychiatrist, psoriasis patients should be provided with mental health assistance, taught to identify psychological stressors and effective strategies to cope with these stressors, and educated about available services, including telemedicine.
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  • 文章类型: Journal Article
    脑电图(EEG)数据的多变量模式分析(MVPA)代表了研究大脑如何编码信息的革命性方法。通过在个体层面考虑时空特征之间的复杂相互作用,MVPA克服了单变量技术的局限性,这往往无法解释显著的个体间和个体内神经变异性。这在研究临床人群时尤其重要,因此,脑电图数据的MVPA最近开始被用作研究脑部疾病认知的工具。这里,我们回顾了这种方法在自闭症等疾病中神经活动异常模式研究中提供的见解,多动症,精神分裂症,诵读困难,神经和神经退行性疾病,在不同的认知领域(感知,注意,记忆,意识)。尽管潜在的缺点应该得到认真解决,这些研究揭示了MVPA在揭示信息处理的功能失调和代偿性神经认知动力学方面的特殊敏感性,通常对传统的单变量方法视而不见。表征个体神经认知谱的这种更高的灵敏度可以提供优化评估和促进个性化干预的独特机会。
    Multivariate pattern analysis (MVPA) of electroencephalographic (EEG) data represents a revolutionary approach to investigate how the brain encodes information. By considering complex interactions among spatio-temporal features at the individual level, MVPA overcomes the limitations of univariate techniques, which often fail to account for the significant inter- and intra-individual neural variability. This is particularly relevant when studying clinical populations, and therefore MVPA of EEG data has recently started to be employed as a tool to study cognition in brain disorders. Here, we review the insights offered by this methodology in the study of anomalous patterns of neural activity in conditions such as autism, ADHD, schizophrenia, dyslexia, neurological and neurodegenerative disorders, within different cognitive domains (perception, attention, memory, consciousness). Despite potential drawbacks that should be attentively addressed, these studies reveal a peculiar sensitivity of MVPA in unveiling dysfunctional and compensatory neurocognitive dynamics of information processing, which often remain blind to traditional univariate approaches. Such higher sensitivity in characterizing individual neurocognitive profiles can provide unique opportunities to optimise assessment and promote personalised interventions.
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  • 文章类型: Journal Article
    这项研究的目的是探索精神科护士在急性单元中照顾幻听患者的经验。使用主题分析进行了定性研究。该研究涉及对18名急性单元护士的半结构化访谈,所有这些护士都为幻听患者提供了干预措施。总的来说,参与者确定了他们在急性单位风险管理中的作用,他们的治疗作用的重要性和对药物管理作为主要护理干预的过度依赖。因此,这些发现证明了护士在急性病房与经历幻听的患者一起工作时面临的个人和职业冲突。护士处于首要位置,可以为急性单元中的幻听患者提供有效的干预和帮助。这项研究的结果表明,心理健康护士可能需要额外的支持和教育,以真正基于康复的方式提供护理,为听到声音的人提供具体干预和参与技能的培训。由于不可预测的环境和有时高风险的工作场所,护士也可以从这一领域的组织援助中受益。
    The aim of this study was to explore psychiatric nurse\'s experiences of caring for people with auditory hallucinations in an acute unit. A qualitative study was conducted using thematic analysis. The study involved semi-structured interviews with 18 acute unit nurses all of whom provided interventions to patients with auditory hallucinations. Overall, participants identified their role in the management of risk within an acute unit, the importance of their therapeutic role and a perceived over-reliance on medication administration as a primary nursing intervention. These findings thus demonstrate the personal and professional conflict that nurses face when working in an acute unit with patients who experience auditory hallucinations. Nurses are in a prime position to provide effective interventions and assistance for people with auditory hallucinations in an acute unit. The findings of this study indicate that mental health nurses may require additional support and education to provide care in a truly recovery-based manner, with training in specific interventions and engagement skills for people who hear voices. Due to an unpredictable environment and sometimes high-risk workplace, nurses may also benefit from organisational assistance in this area.
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  • 文章类型: Journal Article
    背景:对紧急精神病护理的需求正在增加,但在西班牙,对于急诊部门(ED)如何优化精神病患者的护理并没有明确的建议.我们旨在就综合医院急诊科治疗有紧急精神症状的患者的要求提供专家共识建议。
    方法:我们使用了一种改进的Delphi技术。一个科学委员会根据文献检索和临床经验编制了36份声明。这些声明涵盖了组织模式,设施,人员配备,安全,患者干预,和员工培训。由38名具有精神病紧急情况专业知识的精神病学专家组成的小组分两轮对问卷进行了评估。
    结果:经过两轮投票,36个拟议项目中有30个(83%)得到了同意。小组同意精神病紧急情况应在综合医院进行管理,有专门的病人评估设施,直接监督有风险的患者,还有一个由精神病院管理的观察组.除了精神科医生,ED应有24/7全天候的专科护士和安全人员。社会工作者也应该随时可用。ED和咨询室的设计应确保患者和工作人员的安全。应该为有精神病症状的病人建立分诊制度,在精神病学评估之前进行医学评估。关于供应的指导,设备,还提供员工培训。
    结论:综合医院的所有ED都应该有足够的资源来处理任何精神病紧急情况。本文就实现这一目标的最低要求提供了建议。
    BACKGROUND: The demand for urgent psychiatric care is increasing, but in Spain there are no clear recommendations for emergency departments (ED) on how to optimize care for patients with psychiatric emergencies. We aimed to provide expert consensus recommendations on the requirements for general hospitals´ emergency departments to treat patients with urgent psychiatric symptoms.
    METHODS: We used a modified Delphi technique. A scientific committee compiled 36 statements based on literature search and clinical experience. The statements covered the organizational model, facilities, staffing, safety, patient interventions, and staff training. A panel of 38 psychiatry specialists with expertise in psychiatric emergencies evaluated the questionnaire in two rounds.
    RESULTS: After two rounds of voting, 30 out of 36 proposed items (83%) were agreed upon. The panel agreed that psychiatric emergencies should be managed in a general hospital, with dedicated facilities for patient assessment, direct supervision of patients at risk, and an observation unit run by the psychiatric service. In addition to the psychiatrist, the ED should have specialist nurses and security staff available 24/7. Social workers should also be readily available. ED and consulting rooms should be designed to ensure patient and staff safety. A triage system should be established for patients with psychiatric symptoms, with medical evaluation preceding psychiatric evaluation. Guidance on supplies, equipment, and staff training is also provided.
    CONCLUSIONS: All ED in general hospitals should have adequate resources to handle any psychiatric emergency. This paper provides recommendations on the minimum requirements to achieve this goal.
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  • 文章类型: Journal Article
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