Patient specific implant

患者特异性植入物
  • 文章类型: Journal Article
    眼眶骨骼的成功修复通过使眼球位置正常化并使眼外肌完全运动来恢复功能和美容。常规修复是成功的标准植入物。然而,不规则或导致体积不足的缺陷可能难以修复。患者特异性植入物(PSI)的开发在复杂情况下提供了额外的工具。在这里,我们报告了我们使用PSI进行轨道重建的经验。
    对2016年8月至2018年9月接受PSI的连续患者进行了IRB批准的审查。记录人口统计学和检查结果。PSI使用高密度多孔聚乙烯或聚醚醚酮(PEEK)设计并植入修复。对术后病程进行评估,了解结果和并发症。
    确定了8名患者。两个人患有无声窦综合征,3例面部复杂骨折翻修,和3个是肿瘤后重建。七个收到多孔聚乙烯植入物,1有PEEK植入物。平均随访时间为10.2个月(3.3~28.3)。所有都具有改进的功能和美学效果。在60%的骨折和无症状窦患者中,复视和眼球内陷完全解决。所有骨折和无声窦患者在最后一次随访中的主要凝视均为正交性,无复视。肿瘤患者在对称性和功能性方面有所改善。没有并发症。
    复杂的眼眶骨骼错乱可能难以修复,标准植入物可能无法完全解决解剖问题。在具有挑战性的案例中,PSI可以更好地实现美学和解剖学上的成功结果并改善功能。
    UNASSIGNED: Successful repair of the orbital skeleton restores function and cosmesis by normalizing globe position and allowing full motility of the extraocular muscles. Routine repairs are successful with standard implants. However, defects that are irregular or cause volume deficiency can be challenging to repair. The development of patient specific implants (PSI) offers an additional tool in complex cases. Herein, we report our experience using PSI for orbital reconstruction.
    UNASSIGNED: An IRB-approved review was conducted of consecutive patients who received PSI from 8/2016-9/2018. Demographic and examination findings were recorded. PSI was designed using high-density porous polyethylene or polyetheretherketone (PEEK) and implanted for repair. The postoperative course was reviewed for outcomes and complications.
    UNASSIGNED: Eight patients were identified. Two had silent sinus syndrome, 3 were complex facial fracture revisions, and 3 were post-oncologic reconstruction. Seven received porous polyethylene implants, and 1 had a PEEK implant. Mean follow up time was 10.2 months (3.3-28.3). All had an improved functional and aesthetic result. Diplopia and enophthalmos completely resolved in 60% of fracture and silent sinus patients. All fracture and silent sinus patients were orthotropic without diplopia in primary gaze at last follow up. Tumor patients had improvement in symmetry and functionality. There were no complications.
    UNASSIGNED: Complex orbital skeleton derangements can be difficult to repair and standard implants may incompletely resolve the anatomic problem. In challenging cases, PSI may better achieve an aesthetically and anatomically successful outcome and improve functionality.
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  • 文章类型: Journal Article
    这项研究的目的是确定患者是否从二次重建中受益,因为二次重建具有无法改善或恶化其当前状况的风险。对接受个人计算机辅助设计/计算机辅助制造(CAD/CAM)陶瓷植入物治疗的患者进行了综述。为了确定二次重建过程中的变化,研究人员回顾了眼科检查,对轨道进行体积测量,并要求患者在重建前后评估其状况。解决的问题是双重愿景,视敏度,视野,日常生活中的局限性和审美考虑。共有14例患者接受了审查,11例回答了问卷。眼科检查显示眼睛的物理完整性得以保持。术前(33.94±3.24cm3)和术后(30.67±2.07cm3)的体积测量表明,眼眶体积的统计学显着过度校正会导致良好的功能和美学结果。患者的主观意见是他们受益匪浅,尤其是日常生活中的局限性,在10个可能的点中提高了4.4±2.8点,和美学,提高5.9±1.78分。基于这些发现,我们得出的结论是,二次重建有助于改善患者的生活质量,因此应被视为改善患者病情的一种选择。
    The aim of this study was to determine whether patients benefit from a secondary reconstruction since it carries the risks of no improvement or worsening of their current situation. Patients treated with individual computer-aided-design/computer-aided-manufacturing (CAD/CAM) ceramic implants were reviewed. To ascertain changes throughout the secondary reconstruction, the study investigators reviewed ophthalmological examinations, took volumetric measurements of the orbits and asked the patients for evaluation of their situation before and after the reconstruction. Points addressed were double vision, visual acuity, field of vision, limitations in daily life and aesthetic considerations. A total of 14 patients were reviewed and 11 answered the questionnaire. Ophthalmological examinations showed that the physical integrity of the eye was maintained. Volumetric measurements preopeatively (33.94 ± 3.24 cm3) and postoperatively (30.67 ± 2.07 cm3) showed that a statistically significant overcorrection of orbital volume leads to good functional and aesthetic outcomes. Patients\' subjective opinions were that they greatly benefitted, especially concerning limitations in daily life, which improved by 4.4 ± 2.8 points out of 10 possible points, and aesthetics, with an improvement of 5.9 ± 1.78 points. Based on these findings, we conclude that secondary reconstructions contribute to improvement of the patients\' quality of life and therefore should be considered as an option to improve patients\' condition.
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  • 文章类型: Comparative Study
    OBJECTIVE: This study investigated the effect of varying techniques on the surface characteristics of pressed titanium cranioplasty plates, commonly manufactured in laboratory practice. The aim was to highlight the variety of techniques currently used, assess these methods of manufacture and produce manufacturing recommendations.
    METHODS: A questionnaire identified manufacturing methods commonly used by maxillofacial prosthetists. The plate surfaces were examined using scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) spectrometry. The surface differences and titanium compositions were statistically analysed.
    RESULTS: Bead blasting with aluminium oxide (Al2O3) showed a significant decrease (p < 0.001) in titanium surface composition, replaced by a large aluminium content. Trimming tool choice had a significant impact (p = 0.001) on surface contamination by smoothing wheel material deposition; however passivation and anodising techniques had no significant effect (p = 0.293 and p = 0.257, respectively) on the surface composition or roughness of titanium samples.
    CONCLUSIONS: A large range of manufacturing techniques of titanium cranioplasty plates was confirmed and significant differences were found. Amongst other recommendations, bead blasting with Al2O3 is not recommended for commercially pure titanium implant surface finishing due to aluminium contamination. The recommendations outlined will minimise manufacturing time, reduce risk of complication (thus costs) and unify methods to enable a safe, reliable treatment.
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  • 文章类型: Journal Article
    目的:颅骨切除术后颅骨成形术的最佳材料选择仍有待讨论。颅骨成形术后的并发症率往往很高。最近引入了计算机辅助的聚醚醚酮(PEEK)三维建模,用于颅骨重建。这项研究的目的是评估患者和手术相关的特征以及易患颅骨修补术并发症的危险因素。
    方法:这项回顾性研究包括38例患者的40种颅PEEK植入物,2011年至2014年在荷兰的两个参考中心进行。记录并发症,并仔细分析患者和手术相关数据。
    结果:PEEK颅骨修补术的总并发症发生率为28%。并发症包括感染(13%),术后血肿(10%),脑脊液漏(2.5%)和伤口相关问题(2.5%)。所有术后感染都需要移除植入物。尽管如此,移除的植入物可以在重新灭菌后成功地重新使用。
    结论:尽管PEEK颅骨修补术后的总体并发症发生率仍然很高,结果令人满意,因为我们的结果与最近关于颅骨穹顶重建的文献报道相比是有利的。
    OBJECTIVE: The best material choice for cranioplasty following craniectomy remains a subject to discussion. Complication rates after cranioplasty tend to be high. Computer-assisted 3-dimensional modelling of polyetheretherketone (PEEK) was recently introduced for cranial reconstruction. The aim of this study was to evaluate patient- and surgery-related characteristics and risk factors that predispose patients to cranioplasty complications.
    METHODS: This retrospective study included a total of 40 cranial PEEK implants in 38 patients, performed at two reference centers in the Netherlands from 2011 to 2014. Complications were registered and patient- and surgery-related data were carefully analysed.
    RESULTS: The overall complication rate of PEEK cranioplasty was 28%. Complications included infection (13 %), postoperative haematoma (10 %), cerebrospinal fluid leak (2.5 %) and wound-related problems (2.5 %). All postoperative infections required removal of the implant. Nonetheless removed implants could be successfully re-used after re-sterilization.
    CONCLUSIONS: Although overall complication rates after PEEK cranioplasty remain high, outcomes are satisfactory, as our results compare favourably to recent literature reports on cranial vault reconstruction.
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