Pathologists

病理学家
  • 文章类型: Journal Article
    心电病理学,作为远程咨询的一个子集,是远处进行的病理学解释。心电病理学不是一个新现象,但自2015年以来,信息技术和电信的显著进步加上大流行导致了前所未有的复杂性,可访问性,以及心灵感应病理学在人类和兽医学中的应用。此外,远程病理学可以将兽医实践与遥远的实验室联系起来,并为服务不足的动物和社区提供支持。通过我们的范围审查,我们概述了如何在兽医学中使用心灵感应病理学,找出文献中的空白,并强调未来的研究和服务发展领域。我们搜索了MEDLINE,CAB文摘,和灰色文学,包括所有相关文献。尽管在大型兽医诊断实验室中广泛使用数字显微镜,我们发现,描述心灵感应在兽医学中使用的文献很少,在验证全载玻片成像用于主要诊断的研究中存在显著差距。还确定了未充分利用心灵感应病理学来支持在该领域进行的尸检,这表明了服务发展的潜在领域。在兽医学中,心灵感应的使用越来越多,病理学家必须跟上不断变化的技术,确保创新技术的验证,并确定新颖的用途来推进职业发展。
    Telepathology, as a subset of teleconsulting, is pathology interpretation performed at a distance. Telepathology is not a new phenomenon, but since ~2015, significant advances in information technology and telecommunications coupled with the pandemic have led to unprecedented sophistication, accessibility, and use of telepathology in human and veterinary medicine. Furthermore, telepathology can connect veterinary practices to distant laboratories and provide support for underserved animals and communities. Through our scoping review, we provide an overview of how telepathology is being used in veterinary medicine, identify gaps in the literature, and highlight future areas of research and service development. We searched MEDLINE, CAB Abstracts, and the gray literature, and included all relevant literature. Despite the widespread use of digital microscopy in large veterinary diagnostic laboratories, we identified a paucity of literature describing the use of telepathology in veterinary medicine, with a significant gap in studies addressing the validation of whole-slide imaging for primary diagnosis. Underutilization of telepathology to support postmortem examinations conducted in the field was also identified, which indicates a potential area for service development. The use of telepathology is increasing in veterinary medicine, and pathologists must keep pace with the changing technology, ensure the validation of innovative technologies, and identify novel uses to advance the profession.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:子宫内膜增生(EH)的可重复诊断仍然具有挑战性,对患者管理具有潜在意义。本系统综述旨在确定与EH诊断和报告中观察者间变异相关的病理学家特异性因素。
    方法:三个电子数据库,即MEDLINE,Embase和WebofScience,从2000年1月1日至2023年3月25日,使用相关关键字和主题标题进行了搜索。合格的研究报告了影响EH诊断中观察者间差异的病理学家特定因素或工作实践,使用世界卫生组织(WHO)2014或2020分类或子宫内膜样上皮内瘤变(EIN)分类系统。使用QUADAS-2工具进行质量评估,和研究结果进行了叙述综合。
    结果:确定了8项研究。在大多数研究中,即使在专业的妇科病理学家中,观察者之间的差异也很重要。很少有研究调查病理学家的特定特征,但是病理学家被证明有不同的诊断方式,一些人更有可能诊断不足,另一些人可能过度诊断EH。确定了一些新颖的工作实践,例如对核非典型性的“程度”进行分级,并纳入诸如半自动定量图像分析/深度学习模型等客观诊断方法。
    结论:这篇综述强调了病理学家特定因素和工作实践对EH准确诊断的影响,虽然很少有研究。需要进一步的研究来制定更客观的标准,以提高EH诊断报告的可重复性。以及确定新方法的适用性,例如在临床环境中对核异型性程度进行分级。
    OBJECTIVE: Reproducible diagnoses of endometrial hyperplasia (EH) remains challenging and has potential implications for patient management. This systematic review aimed to identify pathologist-specific factors associated with interobserver variation in the diagnosis and reporting of EH.
    METHODS: Three electronic databases, namely MEDLINE, Embase and Web of Science, were searched from 1st January 2000 to 25th March 2023, using relevant key words and subject headings. Eligible studies reported on pathologist-specific factors or working practices influencing interobserver variation in the diagnosis of EH, using either the World Health Organisation (WHO) 2014 or 2020 classification or the endometrioid intraepithelial neoplasia (EIN) classification system. Quality assessment was undertaken using the QUADAS-2 tool, and findings were narratively synthesised.
    RESULTS: Eight studies were identified. Interobserver variation was shown to be significant even amongst specialist gynaecological pathologists in most studies. Few studies investigated pathologist-specific characteristics, but pathologists were shown to have different diagnostic styles, with some more likely to under-diagnose and others likely to over-diagnose EH. Some novel working practices were identified, such as grading the \"degree\" of nuclear atypia and the incorporation of objective methods of diagnosis such as semi-automated quantitative image analysis/deep learning models.
    CONCLUSIONS: This review highlighted the impact of pathologist-specific factors and working practices in the accurate diagnosis of EH, although few studies have been conducted. Further research is warranted in the development of more objective criteria that could improve reproducibility in EH diagnostic reporting, as well as determining the applicability of novel methods such as grading the degree of nuclear atypia in clinical settings.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    本文探讨了远程皮肤病学(TD)在患者护理各个阶段在Mohs显微外科(MMS)中的作用。这项研究旨在评估收益,局限性,以及围绕TD集成到MMS实践的患者经验。我们使用与TD和MMS相关的关键字进行了PubMed搜索,将选定的文章分类为术前,术中,和MMS的术后阶段。TD减少了等待时间(TD为26.10天,面对面[FTF]为60.57天)和咨询失败率(TD为6%与17%为FTF)为MMS术前会诊。它还将治疗时间缩短了两周,并显著节省了旅行(162.7分钟,144.5英里,和每人$60.00)。心电病理学促进了彩信期间的沟通和决策,提高准确性和效率,特别是在具有挑战性的情况下,需要合作的另一个外科医生或病理学家的物理存在是不可行的。81.8%的病例(18/22)经心电病理学明确诊断为良性病变和恶性肿瘤。此外,在肿瘤的常规光学显微镜诊断和心程病理学之间有95%的一致性(19/20),以及所有20个Mohs冻结部分咨询的100%协议。对于术后随访,电话跟进(TFU)和短信被证明是有效的,具有高患者满意度(94%在新西兰和96%在英国)和早期并发症识别成本效益的替代方案。这项研究强调了TD在MMS中的多方面益处:术前增强患者体验,改善手术期间的沟通,和具有成本效益的术后随访。限制包括TD可能出现的财务费用和技术问题(连接问题,视频/音频传输中的延迟,等。).需要进一步的研究来探索术后患者管理中新兴的TD模式。将TD整合到MMS中标志着皮肤病学护理的进步,提供方便,成本效益高,以及更好的解决方案,有可能增强患者的体验和结果。
    This paper explores the role of teledermatology (TD) in Mohs micrographic surgery (MMS) at various stages of patient care. The study aims to assess the benefits, limitations, and patient experiences surrounding TD integration into MMS practices. We conducted a PubMed search using keywords related to TD and MMS, categorizing selected articles into pre-operative, intra-operative, and post-operative stages of MMS. TD reduced waiting times (26.10 days for TD compared to 60.57 days for face-to-face [FTF]) and consultation failure rates (6% for TD vs. 17% for FTF) for MMS preoperative consultations. It also shortened time to treatment by two weeks and led to notable travel savings (162.7 min, 144.5 miles, and $60.00 per person). Telepathology facilitated communication and decision-making during MMS, improving accuracy and efficiency, especially in challenging cases requiring collaboration where physical presence of another surgeon or pathologist is not feasible. Telepathology definitively diagnosed benign lesions and malignant tumors in 81.8% of cases (18/22). Additionally, there was a 95% agreement between conventional light microscopy diagnosis and telepathology in tumors (19/20), and 100% agreement for all 20 Mohs frozen section consultations. For post-operative follow-up, telephone follow-up (TFU) and text messaging proved effective, cost-efficient alternatives with high patient satisfaction (94% in New Zealand and 96% in the U.K.) and early complication identification. This study underscores TD\'s multifaceted benefits in MMS: enhanced patient experience preoperatively, improved communication during surgery, and cost-effective postoperative follow-up. Limitations include the financial expense and technical issues that can arise with TD (connectivity problems, delays in video/audio transmission, etc.). Further studies are needed to explore emerging TD modalities in post-operative patient management. The integration of TD into MMS signifies a progressive step in dermatological care, offering convenient, cost-effective, and better solutions with the potential to enhance patient experiences and outcomes.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    多参数磁共振成像(mpMRI)通过减少不必要的活检数量,改善了具有临床意义的前列腺癌(csPCa)诊断的系统性前列腺活检程序;许多一级证据研究已经证实了MRI靶向活检的准确性,但是,仍然在今天,建议进行系统的前列腺活检,以降低mpMRI的15-20%的假阴性率。已经提出了新的高级成像来检测可疑病变并进行靶向活检,尤其是在无法进行mpMRI时。与传统的TRUS相比,经直肠超声(TRUS)模式正在成为检测PCa的更高灵敏度和特异性的方法;这些技术包括弹性成像和超声造影,以及改进的B型和多普勒技术。可以组合这些模态以定义新的超声方法:多参数超声(mpUS)。最近,微超声(MicroUS)和前列腺特异性膜抗原(PSMA)正电子发射断层扫描/计算机断层扫描(PET/CT)已证明对原发性前列腺病变的检测敏感,从而与原发性前列腺肿瘤的侵袭性高度相关。并行,人工智能正在推进,并开始深刻改变放射学和病理学。在这项研究中,我们讨论了这个角色,Pca新型成像技术的优点和缺点,并讨论未来的方向,包括基于人工智能的技术在成像和组织学中的应用。讨论了这些发现对执业病理学家的意义。
    Multiparametric magnetic resonance imaging (mpMRI) has improved systematic prostate biopsy procedures in the diagnosis of clinically significant prostate cancer (csPCa) by reducing the number of unnecessary biopsies; numerous level one evidence studies have confirmed the accuracy of MRI-targeted biopsy, but, still today, systematic prostate biopsy is recommended to reduce the 15-20% false negative rate of mpMRI. New advanced imaging has been proposed to detect suspicious lesions and perform targeted biopsies especially when mpMRI cannot be performed. Transrectal ultrasound (TRUS) modalities are emerging as methods with greater sensitivity and specificity for the detection of PCa compared to the traditional TRUS; these techniques include elastography and contrast-enhanced ultrasound, as well as improved B-mode and Doppler techniques. These modalities can be combined to define a novel ultrasound approach: multiparametric ultrasound (mpUS). More recently, micro-ultrasound (MicroUS) and prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) have demonstrated to be sensitive for the detection of primary prostatic lesions resulting highly correlated with the aggressiveness of the primary prostatic tumor. In parallel, artificial intelligence is advancing and is set out to deeply change both radiology and pathology. In this study we address the role, advantages and shortcomings of novel imaging techniques for Pca, and discuss future directions including the applications of artificial intelligence-based techniques to imaging as well as histology. The significance of these findings for the practicing pathologist is discussed.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    法医学是人工智能(AI)蓬勃发展的应用领域。的确,自过去十年以来,针对法医病理学家或法医的AI应用已经出现。例如,人工智能模型的开发是为了帮助估计移民或人类遗骸的生物年龄。然而,法医病理学家或医生对人工智能应用程序的使用及其在法医学实践中的整合水平尚未得到很好的描述。因此,对PubMed进行了范围审查,ScienceDirect,和Scopus数据库。这篇评论包括的文章提到了法医病理学家或医生在实践中使用的任何AI应用程序,或者在法医病理学家或医生的一个专业领域中应用的任何AI模型。本评论不包括英语或法语以外的其他语言的文章,或主要处理由非法医病理学家或医生或人工智能专家处理的补充分析,以分析用于法医学研究目的的数据。在每篇文章中,所有相关信息都是从TRIPOD清单中得出和改编的网格分析中检索到的。这篇综述包括35篇文章,并揭示了人工智能应用在死刑学和临床法医学中的发展。然而,这些应用似乎主要停留在研究和开发阶段。的确,由于本文讨论的问题,法医病理学家或医生使用人工智能应用程序是不实际的。最后,人工智能在日常法医学实践中的整合不仅涉及法医病理学家或医生,还涉及法律专业人员。
    Forensic medicine is a thriving application field for artificial intelligence (AI). Indeed, AI applications intended to forensic pathologists or forensic physicians have emerged since the last decade. For example, AI models were developed to help estimate the biological age of migrants or human remains. However, the uses of AI applications by forensic pathologists or physicians and their levels of integration in medicolegal practices are not well described yet. Therefore, a scoping review was conducted on PubMed, ScienceDirect, and Scopus databases. This review included articles that mention any AI application used by forensic pathologists or physicians in practice or any AI model applied in one expertise field of the forensic pathologist or physician. Articles in other languages than English or French or dealing mainly with complementary analyses handled by experts who are not forensic pathologists or physicians or with AI to analyze data for research purposes in forensic medicine were excluded from this review. All the relevant information was retrieved in each article from a grid analysis derived and adapted from the TRIPOD checklist. This review included 35 articles and revealed that AI applications are developed in thanatology and in clinical forensic medicine. However, those applications seem to mainly remain in research and development stages. Indeed, the use of AI applications by forensic pathologists or physicians is not actual due to issues discussed in this article. Finally, the integration of AI in daily medicolegal practice involves not only forensic pathologists or physicians but also legal professionals.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目标:在主流学校中,语言病理学家(SLP)和课堂教师(CT)之间需要跨专业实践(IPP)来支持学生的成绩。此混合方法系统综述旨在综合现有文献,以描述主流学校SLP和CT之间的IPP经验。
    方法:使用系统综述方案对六个数据库进行了全面搜索(PubMedCentral,EMBASE,科克伦图书馆,CINAHLEBSCO,ERIC,和ProQuest学位论文和论文全球)使用与研究问题相关的关键词。共检索到1,876项独特研究。其中,18项研究被确定为与研究问题相关,正如他们描述了SLP和CT之间IPP的经验。采用专题分析法对定量和定性研究进行分析。
    结果:确定了描述IPP经验的六个主要主题:(1)您将什么带入协作表?(2)将价值放在协作中,(3)分享就是合作,(4)合作的性质各不相同,(5)教育背景问题,(6)对专业控制之外的协作的影响。
    结论:SLP和CT之间的IPP是复杂的,在教育背景下出现了各种促进者和IPP的障碍。SLP和CT的能力与有共同的理解,充分的沟通,与彼此建立关系有助于支持学校的IPP。SLP和CT之间以关系为中心的护理方法的利用对于培养和支持学生的成绩也很重要。
    背景:https://doi.org/10.23641/asha.24018732。
    There is an important need for interprofessional practice (IPP) between speech-language pathologists (SLPs) and classroom teachers (CTs) in mainstream schools to support student outcomes. This mixed methods systematic review aimed to synthesize existing literature to describe the experiences of IPP between SLPs and CTs in mainstream schools.
    A systematic review protocol was utilized to conduct a comprehensive search of six databases (PubMed Central, EMBASE, Cochrane Library, CINAHL EBSCO, ERIC, and ProQuest Dissertations & Theses Global) using key words related to the research question. A total of 1,876 unique studies were retrieved. Of these, 18 studies were identified as relevant to the research question, as they described the experiences of IPP between SLPs and CTs. Thematic analysis was used to analyze the quantitative and qualitative studies.
    Six main themes describing IPP experiences were identified: (1) what are you bringing to the collaboration table? (2) putting the value in collaboration, (3) sharing is collaborating, (4) the nature of collaboration varies, (5) the educational context matters, and (6) influences to collaboration beyond professional control.
    IPP between SLPs and CTs is complex, with various facilitators and barriers to IPP emerging within the education context. Competencies for SLPs and CTs related to having a shared understanding, adequate communication, and building relationships with each other help support IPP in schools. The utilization of a relationship-centered care approach between SLPs and CTs is also important to foster and support student outcomes.
    https://doi.org/10.23641/asha.24018732.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    病理学实验室越来越多地使用数字工作流程。这有可能提高实验室效率,但是数字化过程也涉及重大挑战。已经发表了几份报告,描述了特定实验室在数字化过程中的个人经历。然而,仍然缺乏对经验教训的全面概述。我们概述了数字化过程不同方面的经验教训,包括数字案件管理,数字幻灯片阅读,和计算机辅助幻灯片阅读。我们还涵盖了用于监控性能和陷阱以及在实践中观察到的相应值的指标。概述旨在帮助病理学家,IT决策者,和管理员从他人的经验中受益,并以最佳方式实施数字化过程,使自己的实验室面向未来。
    Pathology laboratories are increasingly using digital workflows. This has the potential of increasing laboratory efficiency, but the digitization process also involves major challenges. Several reports have been published describing the individual experiences of specific laboratories with the digitization process. However, a comprehensive overview of the lessons learned is still lacking. We provide an overview of the lessons learned for different aspects of the digitization process, including digital case management, digital slide reading, and computer-aided slide reading. We also cover metrics used for monitoring performance and pitfalls and corresponding values observed in practice. The overview is intended to help pathologists, information technology decision makers, and administrators to benefit from the experiences of others and to implement the digitization process in an optimal way to make their own laboratory future-proof.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Review
    目的:本范围审查旨在探索现有文献中关于语言病理学家(SLPs)和SLP学生在为痴呆症患者(PLWD)提供护理方面的经验和观点。
    方法:使用10个数据库对2000年1月至2022年1月以英文发布的来源进行了系统搜索。如果参与者正在练习SLP和/或参加本科交际障碍或研究生SLP课程的学生,以及在任何临床或教育环境中探索向PLWD提供SLP服务的经验或观点的概念,则包括来源。系统地提取了相关研究特征的包含来源,包括SLP角色和设置,概念域,利用的措施,以及有效痴呆症护理的促进者/障碍。
    结果:29个收录来源中的大部分发表在学术期刊(n=20)或专业组织出版物(n=5)上,并采用横断面研究设计(n=19)。参与者包括SLP(n=22项研究)和研究生(n=6项研究),本科生(n=3个研究),和博士生(n=1研究)。纳入的研究涉及五个主要概念领域:经验,态度,角色,知识,和信心。最常见的障碍和促进有效的痴呆症护理是教育和培训。
    结论:在本范围审查中对当前知识体系的定位和分析揭示了我们建议需要解决的几个知识差距,以满足SLP的教育和培训需求,从而为PLWD提供最佳护理。其中包括系统地衡量跨专业合作环境内外对循证教育和培训计划的访问和结果。
    This scoping review aimed to explore the extant literature on the experiences and views of speech-language pathologists (SLPs) and SLP students regarding the provision of care to people living with dementia (PLWD).
    A systematic search was conducted using 10 databases for sources published in English from January 2000 through January 2022. Sources were included if participants were practicing SLPs and/or students enrolled in undergraduate communicative disorders or graduate SLP programs and if the concepts of experiences or views on the provision of SLP services to PLWD were explored in the context of any clinical or educational setting. Included sources were systematically extracted for pertinent study characteristics, including SLP roles and settings, concept domains, measures utilized, and facilitators/barriers to effective dementia care.
    The majority of the 29 included sources were published in either academic journals (n = 20) or professional organization publications (n = 5) and used a cross-sectional study design (n = 19). Participants included SLPs (n = 22 studies) and graduate (n = 6 studies), undergraduate (n = 3 studies), and doctoral students (n = 1 study). The included studies addressed five primary conceptual domains: experiences, attitudes, roles, knowledge, and confidence. The most commonly addressed barriers and facilitators of effective dementia care were education and training.
    Mapping and analysis of the current body of knowledge within this scoping review illuminated several knowledge gaps that we propose need to be addressed to meet the education and training needs of SLPs to provide optimal care to PLWD. These include systematically measuring access to and outcomes of evidence-based education and training programs both within and outside of an interprofessional collaborative context.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Review
    在临床实践中,寿命终止法管理寿命终止决策。对与从事临终护理的专职医疗专业人员有关的具体法律问题几乎没有分析。
    进行了范围审查,以确定和检查范围,范围,以及与澳大利亚语言病理学家和社会工作者的临终实践有关的法律问题的文献的性质,包括目前的差距。通过搜索六个电子数据库来识别文献,谷歌学者,相关专业组织和州/地区卫生部门的网站,扫描参考列表,并借鉴现有知识。进行了数据图表和调查结果的主题分析。
    包括20份文件,跨越各种文档类型。大多数侧重于成人临床实践。文件表明,这两个职业遇到了类似的法律问题。
    文献中存在关键空白。调查结果将告知这些专业人士与他们的临床实践相关的法律问题,并为进一步的资源开发提供信息。
    UNASSIGNED: End-of-life law governs end-of-life decision-making in clinical practice. There has been little analysis of the specific legal issues relevant to allied health professionals working in end-of-life care.
    UNASSIGNED: A scoping review was undertaken to identify and examine the extent, range, and nature of literature on the legal issues relevant to end-of-life practice for Australian speech-language pathologists and social workers, including current gaps. Literature was identified by searching six electronic databases, Google Scholar, the websites of relevant professional organisations and State/Territory health departments, scanning reference lists, and drawing on existing knowledge. Data charting and thematic analysis of findings was performed.
    UNASSIGNED: Twenty documents were included, spanning various document types. Most focused on adult clinical practice. Documents demonstrated that the two professions encounter similar legal issues.
    UNASSIGNED: Key gaps exist in the literature. Findings will inform these professionals of the legal issues relevant to their clinical practice and inform the development of further resources.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Review
    结直肠癌(CRC)是全球最常见的癌症之一,其诊断和分类对于病理学家和影像学专家来说仍然具有挑战性。使用人工智能(AI)技术,特别是深度学习,已成为一种潜在的解决方案,以提高分类的准确性和速度,同时保持护理质量。在这次范围审查中,我们旨在探索深度学习在不同类型大肠癌分类中的应用。我们检索了5个数据库,选择了45个符合纳入标准的研究。我们的结果表明,深度学习模型已被用于使用各种类型的数据对结直肠癌进行分类,组织病理学和内窥镜图像是最常见的。大多数研究使用CNN作为他们的分类模型。我们的发现概述了深度学习在结直肠癌分类中的研究现状。
    Colorectal cancer (CRC) is one of the most common cancers worldwide, and its diagnosis and classification remain challenging for pathologists and imaging specialists. The use of artificial intelligence (AI) technology, specifically deep learning, has emerged as a potential solution to improve the accuracy and speed of classification while maintaining the quality of care. In this scoping review, we aimed to explore the utilization of deep learning for the classification of different types of colorectal cancer. We searched five databases and selected 45 studies that met our inclusion criteria. Our results show that deep learning models have been used to classify colorectal cancer using various types of data, with histopathology and endoscopy images being the most common. The majority of studies used CNN as their classification model. Our findings provide an overview of the current state of research on deep learning in the classification of colorectal cancer.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号