Pain control

疼痛控制
  • 文章类型: Journal Article
    背景:与年轻患者相比,老年人的创伤死亡率更高。衰老与多个系统的生理变化相关,并与虚弱相关。虚弱是老年创伤患者死亡的危险因素。我们旨在为老年创伤患者的管理提供循证指南,以改善其并减少徒劳的程序。
    方法:六个专家急性护理和创伤外科医师工作组根据主题和指定的PICO问题广泛审查了文献。根据GRADE方法对声明和建议进行了评估,并在2023年WSES第十届国际大会上获得了该领域专家的共识。
    结果:老年创伤患者的管理需要了解衰老生理学,集中的分诊,包括药物史,脆弱评估,营养状况,早期启动创伤治疗方案以改善预后。老年人的急性创伤疼痛必须通过多模式镇痛方法来管理,以避免使用阿片类药物的副作用。建议在穿透性(腹部,胸)创伤,严重烧伤和开放性骨折的老年患者减少脓毒症并发症。在没有败血症和脓毒性休克迹象的钝性创伤中不推荐使用抗生素。高危和中危老年创伤患者应根据肾功能情况尽早使用LMWH或UFH预防静脉血栓栓塞,患者体重和出血风险。姑息治疗小组应尽快参与,以考虑患者的指示,以多学科方法讨论生命的终结。家庭感情和代表的欲望,所有的决定都应该分享。
    结论:老年创伤患者的管理需要了解衰老生理学,基于评估虚弱和创伤早期激活方案的重点分诊,以改善结局。需要老年重症监护病房以多学科方法护理老年和虚弱的创伤患者,以降低死亡率并改善预后。
    The trauma mortality rate is higher in the elderly compared with younger patients. Ageing is associated with physiological changes in multiple systems and correlated with frailty. Frailty is a risk factor for mortality in elderly trauma patients. We aim to provide evidence-based guidelines for the management of geriatric trauma patients to improve it and reduce futile procedures.
    Six working groups of expert acute care and trauma surgeons reviewed extensively the literature according to the topic and the PICO question assigned. Statements and recommendations were assessed according to the GRADE methodology and approved by a consensus of experts in the field at the 10th international congress of the WSES in 2023.
    The management of elderly trauma patients requires knowledge of ageing physiology, a focused triage, including drug history, frailty assessment, nutritional status, and early activation of trauma protocol to improve outcomes. Acute trauma pain in the elderly has to be managed in a multimodal analgesic approach, to avoid side effects of opioid use. Antibiotic prophylaxis is recommended in penetrating (abdominal, thoracic) trauma, in severely burned and in open fractures elderly patients to decrease septic complications. Antibiotics are not recommended in blunt trauma in the absence of signs of sepsis and septic shock. Venous thromboembolism prophylaxis with LMWH or UFH should be administrated as soon as possible in high and moderate-risk elderly trauma patients according to the renal function, weight of the patient and bleeding risk. A palliative care team should be involved as soon as possible to discuss the end of life in a multidisciplinary approach considering the patient\'s directives, family feelings and representatives\' desires, and all decisions should be shared.
    The management of elderly trauma patients requires knowledge of ageing physiology, a focused triage based on assessing frailty and early activation of trauma protocol to improve outcomes. Geriatric Intensive Care Units are needed to care for elderly and frail trauma patients in a multidisciplinary approach to decrease mortality and improve outcomes.
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  • 文章类型: Journal Article
    目的:我们概述了2024年欧洲泌尿外科协会(EAU)/欧洲儿科泌尿外科学会(ESPU)儿科泌尿外科指南的更新,为围手术期管理提供循证标准。微创手术(MIS),鞘膜积液,先天性下尿路梗阻(CLUTO),创伤/紧急情况,和生育力保护。
    方法:对每种情况进行了广泛的文献检索。根据证据的质量制定了建议,并将其评为强或弱,利益/伤害比,和潜在的患者偏好。
    围手术期管理建议包括与禁食有关的要点,术前用药,抗生素预防,疼痛控制,需要全身麻醉的患者的血栓预防。MIS在儿科泌尿科的使用正在增加,在不同的MIS方法之间没有观察到重大差异。对于鞘膜积液,观察是最初推荐的方法。对于持续的情况,治疗根据鞘膜积液的类型而变化。CLUTO病例应在具有产前和产后管理多学科专业知识的三级中心进行管理。新生儿瓣膜消融仍是治疗的主要手段,但相关的膀胱功能障碍需要持续治疗。在泌尿系统创伤和紧急情况中,肾损伤仍然是发病和死亡的重要原因。保守管理已成为血液动力学稳定儿童的标准方法。缺血性阴茎异常勃起是一种医疗紧急情况,需要逐步管理。非缺血性阴茎异常勃起的初始治疗是保守的。由于接受性腺毒性疗法的癌症幸存者数量不断增加,青春期前儿童和青少年的生育力保护已成为一个日益相关的问题。一个主要的限制是相关文献的匮乏。
    结论:此2024EAU/ESPU指南摘要为某些儿科泌尿系统疾病的循证管理提供了最新指导。
    结果:我们提供了最新的欧洲泌尿外科协会/欧洲儿科泌尿外科学会儿科泌尿外科指南的摘要。有关于手术前和手术后立即采取的步骤的建议,鞘膜积液的管理,先天性下尿路梗阻,泌尿系统创伤/紧急情况,以及保存生育能力。建议是基于对最近研究的全面审查。
    OBJECTIVE: We present an overview of the 2024 updates for the European Association of Urology (EAU)/European Society for Paediatric Urology (ESPU) guidelines on paediatric urology to offer evidence-based standards for perioperative management, minimally invasive surgery (MIS), hydrocele, congenital lower urinary tract obstruction (CLUTO), trauma/emergencies, and fertility preservation.
    METHODS: A broad literature search was performed for each condition. Recommendations were developed and rated as strong or weak on the basis of the quality of the evidence, the benefit/harm ratio, and potential patient preferences.
    UNASSIGNED: Recommendations for perioperative management include points related to fasting, premedication, antibiotic prophylaxis, pain control, and thromboprophylaxis in patients requiring general anaesthesia. MIS use is increasing in paediatric urology, with no major differences observed among different MIS approaches. For hydrocele, observation is the initial approach recommended. For persistent cases, treatment varies according to the type of hydrocele. CLUTO cases should be managed in tertiary centres with multidisciplinary expertise in prenatal and postnatal management. Neonatal valve ablation remains the mainstay of treatment, but associated bladder dysfunction requires continuous treatment. Among urological traumas and emergencies, renal trauma is still an important cause of morbidity and mortality. Conservative management has become the standard approach in haemodynamically stable children. Ischaemic priapism is a medical emergency and requires stepwise management. Initial management of nonischaemic priapism is conservative. Fertility preservation in prepubertal children and adolescents has become an increasingly relevant issue owing to the ever-increasing number of cancer survivors receiving gonadotoxic therapies. A major limitation is the scarcity of relevant literature.
    CONCLUSIONS: This summary of the 2024 EAU/ESPU guidelines provides updated guidance for evidence-based management of some paediatric urological conditions.
    RESULTS: We provide a summary of the updated European Association of Urology/European Society for Paediatric Urology guidelines on paediatric urology. There are recommendations on steps to take before and immediately after surgery, management of hydrocele, congenital lower urinary tract obstruction, and urological trauma/emergencies, as well as preservation of fertility. Recommendations are based on a comprehensive review of recent studies.
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  • 文章类型: Journal Article
    氯胺酮是苯环利定(PCP)衍生物,主要用作非竞争性N-甲基-D-天冬氨酸(NMDA)受体拮抗剂。氯胺酮作为镇痛药和产生有效镇痛的分离镇静剂,镇静,和健忘症,同时保持自发的呼吸驱动。随着多项研究证明其可靠的功效和广泛的安全范围,它在疼痛管理中迅速获得认可。本文回顾了其中的一些研究,氯胺酮的历史,及其药理和药代动力学特性。本文还讨论了氯胺酮在创伤环境中的使用,包括联合削减,程序,镇静,和疼痛控制,以及剂量建议。
    Ketamine is a phencyclidine (PCP) derivative, which primarily acts as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Ketamine serves as an analgesic and a dissociative sedative that produces potent analgesia, sedation, and amnesia while preserving spontaneous respiratory drive. It is rapidly gaining acceptance in the management of pain as multiple studies have demonstrated its reliable efficacy and a wide margin of safety. This article reviews some of these studies, the history of ketamine, and its pharmacological and pharmacokinetic properties. The article also discusses the use of ketamine in the trauma setting, including joint reductions, procedures, sedation, and pain control, as well as dosing recommendations.
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  • 文章类型: Journal Article
    所有创伤的15%和胸部创伤的60%患者存在肋骨骨折。孤立的肋骨骨折不会危及生命,但它们可能非常痛苦,导致夹板和呼吸功能受损。夹板限制了病人深呼吸的能力,导致肺不张,肺不张至分泌物去除不良,分泌物去除不良会导致肺炎。肺炎是肋骨骨折患者呼吸衰竭的常见途径。值得注意的是,在老年人中,每次肋骨骨折增加27%的肺炎和19%的死亡风险。从公共卫生的角度来看,肋骨骨折具有长期影响,只有59%的患者在6个月后恢复工作。在这篇综述中,我们将研究目前与肋骨骨折相关的疼痛管理有关的最新技术。本概述将简要介绍胸部的解剖结构和一些重要的生理概念。治疗肋骨疼痛的药理学和非侵入性手段的最新趋势,硬膜外麻醉的特殊部分,一些其他的侵入性疼痛控制方法,并回顾了最近关于肋骨电镀的文献。最后,一个实用的,易于遵循的指导方针,将介绍治疗肋骨骨折疼痛的患者。
    Rib fractures are present in 15% of all traumas and 60% of patients with chest traumas. Rib fractures are not life-threatening in isolation, but they can be quite painful which leads to splinting and compromise of respiratory function. Splinting limits the ability of a patient to take a deep breath, which leads to atelectasis, atelectasis to poor secretion removal, and poor secretion removal leads to pneumonia. Pneumonia is the common pathway to respiratory failure in patients with rib fractures. It is noted that in the elderly, each rib fracture increases developing pneumonia by 27% and the risk of dying by 19%. From a public health perspective, rib fractures have long-term implications with only 59% of patients returning to work at 6 months. In this review we will examine the state of art as it currently exists with regard to the management of pain associated with rib fractures. Included in this overview will be a brief review of the anatomy of the thorax and some important physiologic concepts, the latest trends in pharmacologic and noninvasive means of managing rib pain, a special section on epidural anesthesia, some other alternative invasive methods of pain control, and a review of the recent literature on rib plating. Finally, a practical, easy to follow guideline, to manage the patient with pain from rib fractures will be presented.
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  • 文章类型: Journal Article
    为手部烧伤患者制定循证护理指南。
    综合审查。
    搜索的是EMBASE,PubMed,WebofScience,Scopus,临床关键,Iranmedex,马吉兰,科学信息数据库(SID)Cochran,CINAHL和谷歌学者数据库从2000年1月至2019年8月。随着研究小组的形成,两名研究人员独立选择了符合条件的研究.最初的搜索结果是2,230条记录;最终,根据研究的纳入和排除标准筛选记录后,将40篇文章确定为综述。用MMAT方法评价所选研究的质量。
    选定研究的数据综合,通过突出显示文本的相关部分来编码,并为这些区域分配代码字。在此之后,使用恒定的比较来通过组合代码来开发类别。最后,手烧伤护理指南是通过将描述性主题分为两个主要阶段来制定的。
    这项审查结果表明,基于证据的指南为医疗团队提供了高质量的建议,提高了临床护理质量。由于在我们的背景下缺乏既定的指导方针,使用循证指南管理烧伤手似乎很有帮助.
    To develop an evidence-based guideline to care for hand-burned patients.
    An integrative review.
    The search was conducted of EMBASE, PubMed, Web of Science, SCOPUS, Clinical Key, Iranmedex, Magiran, Scientific Information Database (SID), Cochran, CINAHL and Google Scholar databases from January 2000-August 2019. Following the formation of the research team, two researchers independently selected the eligible studies. The initial search resulted in 2,230 records; ultimately, 40 articles were identified to be the review after screening the records based on the study\'s inclusion and exclusion criteria. Quality of selected studies was evaluated with the MMAT method.
    Data syntheses of selected studies, coded by highlighting the relevant parts of the text, and assigning code words to these areas were done. Following this, a constant comparison was used to develop categories by combining codes. Finally, hand burns nursing care guideline was developed by categorizing descriptive themes in two main phases.
    This review results have shown that evidence-based guidelines present high-quality recommendations for the healthcare team, which improves the quality of clinical care. Due to a lack of established guidelines in our context, it seems to be helpful to use evidence-based guidelines in managing burned hands.
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  • 文章类型: Journal Article
    UNASSIGNED: In the midst of the nationwide opioid epidemic, our institution began an effort to improve the education of opioid prescribers and disseminate procedure-specific guidelines for the number of opioid pills to prescribe post-operatively for total joint arthroplasty. The number of opioid pills suggested for total hip or knee replacement was 70 tablets.
    UNASSIGNED: We sought to evaluate the impact of the new institutional guideline on opioid prescribing practices, hypothesizing that it would lead to a decrease in the number of pills prescribed but an increase in patient call volume after discharge.
    UNASSIGNED: After the new guidelines were implemented in February 2018, we retrospectively reviewed all opioid prescriptions written for patients on the joint-replacement service from March 2016 to March 2018. In addition, we tabulated post-operative telephone calls made to the nurse practitioner service before and after guideline implementation. The majority of calls to the nurse practitioner service are for opioid renewals.
    UNASSIGNED: We included 9514 patients in the analysis. Prior to guideline implementation, the mean number of pills prescribed after primary total joint arthroplasty was 91 ± 26.6 pills and after it was 65 ± 16.3 pills. The monthly number of unique patient telephone interactions was statistically significantly lower after the implementation of the new guidelines.
    UNASSIGNED: An institutional guideline for opioid prescribing after total joint arthroplasty significantly reduced the number of pills prescribed to patients without causing a significant increase in the number of phone calls to the service.
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  • 文章类型: Journal Article
    Cancer is a major public health issue. Poor pain management has devastating consequences that seriously affect quality of life, diminish functionality and place a huge emotional burden on patients and their relatives. A group of Latin American opinion leaders were invited to participate in a meeting to discuss areas associated with cancer pain. The expert panel reviewed the latest literature to draft region-specific guidelines for effective pain management. The guidelines make recommendations on tailoring treatment to the specific type of pain and provide local physicians with the state-of-the art findings in the field. Management should be with pharmacological approaches (nonopioid, adjuvant and opioid analgesics, as well as oncologic therapies and interventional procedures) and nonpharmacological approaches.
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  • 文章类型: Journal Article
    Effective perioperative pain management techniques and accelerated rehabilitation programs can improve health-related quality of life and functional status of patients after total hip arthroplasty. Traditionally, postoperative analgesia following arthroplasty was provided by intravenous patient-controlled analgesia or epidural analgesia. Recently, peripheral nerve blockade has emerged alternative analgesic approach. Multimodal analgesia strategy combines analgesics with different mechanisms of action to improve pain management. Intraoperative periarticular injection of multimodal drugs is one of the most important procedures in perioperative pain control for total hip arthroplasty. The goal of this review article is to provide a concise overview of the principles of multimodal pain management regimens as a practical guide for the perioperative pain management for total hip arthroplasty.
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  • 文章类型: Journal Article
    The Wilderness Medical Society convened an expert panel to develop evidence-based guidelines for the management of pain in austere environments. Recommendations are graded on the basis of the quality of supporting evidence as defined by criteria put forth by the American College of Chest Physicians. This is an updated version of the original WMS Practice Guidelines for the Treatment of Acute Pain in Remote Environments published in Wilderness & Environmental Medicine 2014;25(1):41-49.
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  • 文章类型: Journal Article
    荒野医学会召集了一个专家小组,为严峻环境中的疼痛管理制定循证指南。建议根据美国胸科医师学会提出的标准所定义的支持证据的质量进行分级。
    The Wilderness Medical Society convened an expert panel to develop evidence-based guidelines for the management of pain in austere environments. Recommendations are graded based on the quality of supporting evidence as defined by criteria put forth by the American College of Chest Physicians.
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