背景:眼球运动功能容易受到神经损伤,因为它需要很大一部分大脑回路,包括大脑的每个叶,脑干,丘脑,基底神经节,小脑,颅神经和视束。虽然关于轻度创伤性脑损伤(mTBI)后眼部运动障碍频率高的报道涵盖了多学科期刊,没有对标志进行范围审查,诊断评估和标准,以及mTBI后眼部运动障碍的适当管理。据报道,mTBI后的眼运动功能障碍对积极治疗有反应。这项范围审查的目的是绘制目前用于儿童和成人mTBI相关眼部运动障碍管理的诊断评估和治疗方式的可用证据。本范围审查还旨在确定当前文献中的差距,并为未来的研究提供建议。
方法:本综述将包括报告有脑震荡和/或mTBI的人群,没有年龄限制,种族,受伤后的性别或时间。该审查将评估报告的与眼运动功能障碍有关的症状,使用的评估类型和诊断标准,报告的治疗方法,以及支持报告治疗的证据水平。这篇综述将排除有关非创伤性病因和中度/重度创伤性脑损伤的脑损伤的文献。mTBI后的眼部运动功能障碍出现在多个学科的期刊上。因此,将评估多个数据库,包括Pubmed,Embase,PEDro,OVID,临床关键,谷歌学者和REHABDATA。从开始到现在,将搜索文献。证据来源将包括实验研究设计,包括随机对照试验,非随机对照试验和中断时间序列。此外,分析性观察研究,包括前瞻性和回顾性队列研究,案例系列,将考虑纳入横断面研究和临床实践指南.将在临床表现上提取数据,频率,评估,脑震荡和mTBI相关眼运动障碍的诊断标准管理策略和结果。
背景:此范围界定审查将使用来自现有出版物的数据,并且不需要机构审查委员会的道德批准。结果将通过发表在同行评审的科学期刊上进行传播,并在相关会议上以及作为未来研讨会的一部分,与参与mTBI患者诊断和管理的专业人员一起进行。
Ocular motor function is susceptible to neurological injury because it requires a large portion of brain circuitry including every lobe of the brain, brainstem, thalamus, basal ganglia, cerebellum, cranial nerves and visual tracts. While reports of a high frequency of ocular motor dysfunctions after mild traumatic brain injury (mTBI) span multidisciplinary journals, there is no scoping review of the signs, diagnostic assessments and criteria, and appropriate management of ocular motor disorders post-mTBI. Post-mTBI ocular motor dysfunction has been reported to respond to active treatment. The objective of this scoping
review is to map the available evidence on the diagnostic assessment and treatment modalities currently used in the management of mTBI-related ocular motor disorders in children and adults. This scoping
review also aims to identify gaps in the current literature and provide suggestions for future research.
This
review will include populations with reported concussion and/or mTBI without restrictions on age, race, sex or time since injury. The
review will evaluate the reported symptoms related to ocular motor dysfunction, types of assessments and diagnostic criteria used, reported treatments, and the level of evidence supporting the reported treatments. This review will exclude literature on brain injury of non-traumatic aetiology and moderate/severe traumatic brain injury. Ocular motor dysfunction after mTBI appears in journals across multiple disciplines. Thus, multiple databases will be evaluated including Pubmed, Embase, PEDro, OVID, Clinical Key, Google Scholar and REHABDATA. Literature will be searched from inception to present day. Evidence sources will include experimental study designs including randomised controlled trials, non-randomised controlled trials and interrupted time-series. Additionally, analytical observational studies including prospective and retrospective cohort studies, case series, cross-sectional studies and clinical practice guidelines will be considered for inclusion. Data will be extracted on clinical presentation, frequency, assessment, diagnostic criteria management strategies and outcomes of concussion and mTBI-related ocular motor disorders.
This scoping review will use data from existing publications and does not require ethical approval by an institutional
review board. Results will be disseminated through publication in a peer-reviewed scientific journal and presented at relevant conferences and as part of future workshops with professionals involved with diagnosis and management of patients with mTBI.