UNASSIGNED:新的证据强调了环境污染与几种心血管疾病(CVD)的可能联系。本研究旨在探讨短期空气污染暴露对合肥市冠心病住院的影响。
UNASSIGNED:从安徽医科大学第一附属医院获取2014-2021年每日冠心病住院人数数据。大气污染物和气象数据分别从中国环境监测总站和中国气象数据服务中心获得,分别。使用分布滞后非线性模型(DLNM)和泊松广义线性回归评估空气污染与冠心病住院之间的相关性。
未经评估:在单污染物模型中,NO2,O3和CO与冠心病住院率密切相关。具体来说,暴露于NO2(lag0,相对风险[RR]:1.013,95CI:1.002-1.024,每10μg/m3增加)和CO(lag13,RR:1.035,95CI:1.001-1.071,每1μg/m3增加)显示与CHD住院率增加呈正相关.有趣的是,O3与CHD的住院具有保护性关联(lag0,RR:0.993,95CI:0.988-0.999,每增加10μg/m3)。类似的结果,对于单污染物模型来说,在使用双污染物模型进行验证后发现。亚组分析表明,年轻人,女人,炎热季节的人们更容易接触NO2,而老年人,女人,寒冷季节的人更容易受到O3的影响。此外,老年人更容易接触一氧化碳.
未经评估:总的来说,暴露于NO2和CO会增加冠心病住院率,但暴露于O3显示了与CHD住院率的保护性关联。因此,应采取早期空气污染物预防措施,以保护易感的CHD患者.
Emerging evidence has highlighted the possible links of environmental pollution with several cardiovascular diseases (CVDs). The current
study aimed to explore the impact of short-term air pollution exposure on CHD hospitalization in Hefei.
Data about the daily number of CHD admissions (from 2014 to 2021) were retrieved from the First Affiliated Hospital of Anhui Medical University. Air pollutants and meteorological data were obtained from the China Environmental Monitoring Station and the China Meteorological Data Service Center, respectively. The correlation between air pollution and CHD hospitalization was assessed using distributed lag non-linear model (DLNM) and Poisson generalized linear regression.
In the single-pollutant model, NO2,
O3, and CO strongly correlated with CHD hospitalization rate. Specifically, exposure to NO2 (lag0, relative risk [RR]: 1.013, 95%CI: 1.002-1.024, per 10 μg/m3 increase) and CO (lag13, RR: 1.035, 95%CI: 1.001-1.071, per 1 μg/m3 increase) revealed a positive correlation with an increased rate of CHD hospitalization. Interestingly,
O3 had a protective association with hospitalization of CHD (lag0, RR: 0.993, 95%CI: 0.988-0.999, per 10 μg/m3 increase). Similar results, to those of the single-pollutant model, were revealed following verification using two-pollutant models. Subgroup analyses indicated that young people, women, and people in hot seasons were more susceptible to NO2 exposure, while the elderly, women, and people in cold seasons were more susceptible to
O3. Furthermore, the elderly were more susceptible to CO exposure.
Overall, exposure to NO2 and CO increases the rate of CHD hospitalization, but exposure to
O3 shows a protective association with the rate of CHD hospitalization. Therefore, early preventive measures against air pollutants should be applied to protect vulnerable patients with CHD.