Mites

  • 文章类型: Journal Article
    皮肤镜检查已用于非侵入性诊断。一些研究已经评估了该工具在诊断中的有用性,然而,不同研究之间使用的金标准(SSSB或KOH检验)和阳性标准存在差异.添加到此,在临床可观察和相关范围内缺乏对皮肤镜体征有用性的控制和客观量化。通过计算不同皮肤镜征象的性能指标,验证皮肤镜检查对痴呆诊断的有用性。回顾性病例对照研究,其中包括怀疑有痴呆病的成年人。获得健康和病变皮肤的皮肤镜照片和刮擦。样品由受过训练的人员进行显微分析。通过确定蠕形螨尾巴(DT)的存在来评估照片,在预定范围内扩张的卵泡开口(DFO)和扩张的血管(DBV)。包括64名患者(总共=256个样本);在69%中观察到在皮肤刮擦上存在蠕形螨。在皮肤镜下,DT的存在范围为11-20/视野,其阳性似然比(LR)为12.10(95CI6.52-22.45),阴性LR为0.32(95CI0.23-0.45).皮肤镜下至少一个阳性信号的组合和二分法性能(DT>10/场,DFO>10/场或DBV>场的50%):正LR7.14(95CI4.80-10.62)和负LR0.11(95CI0.06-0.22)。DT的存在,DFO或DBV与螨试验阳性有很高的相关性,因此,只有通过皮肤镜检查才能对该病进行诊断。
    Dermoscopy has been used for the non-invasive diagnosis of demodicosis. Several studies have evaluated the usefulness of this tool in the diagnosis, however, there are differences in the gold standard (SSSB or KOH test) and criteria of positivity used between studies. Added to this, is the lack of controls and objective quantification of the usefulness of dermoscopic signs in clinically observable and relevant ranges. To validate the usefulness of dermoscopy for the diagnosis of demodicosis by calculating the performance indicators for the different dermoscopic signs. Retrospective intrapatient case-control study, which included adults with suspicion of demodicosis. Dermoscopic photographs and scraping of healthy and lesional skin were obtained. Samples were analyzed microscopically by trained personnel. Photographs were evaluated by determining the presence of Demodex tails (DT), dilated follicular openings (DFO) and dilated blood vessels (DBV) in pre-defined ranges. 64 patients were included (total = 256 samples); the presence of demodex on skin scraping was seen in 69%. Under dermoscopy, the presence of DT in range 11-20/field had a positive likelihood ratio (LR) of 12.10 (95%CI 6.52-22.45) and negative LR 0.32 (95%CI 0.23-0.45). Combined and dichotomized performance for at least one positive sign under dermoscopy (DT > 10/field, DFO > 10/field or DBV > 50% of the field): positive LR 7.14 (95%CI 4.80-10.62) and negative LR 0.11 (95%CI 0.06-0.22). The presence of DT, DFO or DBV has a high correlation with a positive mite test, so the diagnosis of demodicosis could be made only through dermoscopy.
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  • 文章类型: Journal Article
    蠕形螨的增殖通常与酒渣鼻的发病机理有关。蠕形螨识别的黄金标准是标准化皮肤表面活检的显微镜检查。然而,这种采样方法可能令人痛苦和痛苦,尤其是在毛茸茸的地方进行时。在这项病例对照研究中,我们比较了PCR和显微镜检查诊断蠕形螨感染的敏感性。此外,我们调查了蠕形螨的存在与临床特征之间的可能相关性.总的来说,包括20例受丘疹性酒渣鼻影响的患者和10例对照。在显微镜检查和PCR中,酒渣鼻患者头皮和面部的阳性样本患病率高于对照组.显微镜在面部的敏感度为50%,在头皮的敏感度为46.7%。PCR在面部的灵敏度为93.75%,在头皮的灵敏度为86.7%。PCR阳性与面部丘疹和脓疱的发生频率较高有关。面部阳性的患者头皮阳性的频率更高。头皮可以代表蠕形螨的储库,应该用敏感和无痛的方法进行调查。应进一步研究对无痛收集的样品进行的PCR。
    Demodex mite proliferation is frequently involved in the pathogenesis of rosacea. The gold standard for Demodex identification is microscopic examination on a standardized skin surface biopsy. However, this method of sampling can be distressing and painful, especially when performed on hairy sites. In this case-control study, we compared the sensitivity of PCR and microscopic examination in diagnosing a Demodex infestation. Moreover, we investigated the possible correlations between the presence of Demodex mites and clinical characteristics. In total, 20 patients affected by papulopustular rosacea and 10 controls were included. At both microscopic examination and PCR, patients with rosacea presented a greater prevalence of positive samples than controls at the scalp and at the face. Microscopy had sensitivity of 50% at the face and of 46.7% at the scalp. PCR had sensitivity of 93.75% at the face and of 86.7% at the scalp. The positivity of PCR was associated to a higher frequency of facial papules and pustules. Patients with positivity at the face had a more frequent positivity at the scalp. The scalp could represent a reservoir for the Demodex mites, and should be investigated by sensitive and painless methods. PCR performed on painlessly collected samples should be further investigated.
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  • 文章类型: Journal Article
    BoryTucholskie国家公园,成立于1996年,是波兰最近建立的国家公园之一,因此,还没有被彻底检查。本研究的作者介绍了他们关于Uropodina亚目(Acari:Mesostigmata)螨群落的研究结果,居住在BoryTucholskie国家公园区域内的鸟类筑巢箱。螨群落由两个天然物种组成,即Leiodinychusorbicularis(C.L.Koch,1839年)和Chiropturopodanidiphila(Winiewski和Hirschmann,1993年)。前者是具有各种巢穴特征的物种,以及嵌套的盒子,它通常是eudominant物种。后者是Uropodina极为稀有和稀缺的物种,迄今已知不属于啄木鸟的空洞。在BoryTucholskie国家公园领域的分析社区中,L.orbicularis的种群估计超过6,000个标本,在Ch的情况下。nidiphia-超过400个标本。
    Bory Tucholskie National Park, founded in 1996, is one of the most recently established national parks in Poland, and therefore, has not been thoroughly examined yet. The authors of the current study present results of their research concerning communities of mites from the suborder Uropodina (Acari: Mesostigmata), inhabiting bird nesting boxes within the area of Bory Tucholskie National Park. The mite community comprises two nidicolous species, i.e. Leiodinychus orbicularis (C.L. Koch, 1839) and Chiropturopoda nidiphila (Wiśniewski and Hirschmann 1993). The former is a species characteristic of various types of nests, as well as nesting boxes, where it is usually the eudominant species. The latter is an extremely rare and scarce species of Uropodina, known thus far from woodpeckers\' hollows. The population of L. orbicularis in the analysed communities in the realm of Bory Tucholskie National Park has been estimated to be over 6,000 specimens, and in the case of Ch. nidiphila - over 400 specimens.
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  • 文章类型: Journal Article
    人类蠕形螨是生活在毛囊皮脂腺单位中的寄生虫,可引起群虫病。虽然痴呆可能是一种原发性皮肤病,它也可能导致免疫抑制和局部或全身免疫抑制疗法。手术隆鼻是最常见的整容手术之一,它是各种皮肤并发症的原因,尤其是痤疮,因为它会影响皮肤的附件结构。因此,这项研究旨在调查手术鼻整形患者的皮肤变化是否使他们容易受到蠕形螨感染。
    接受过隆鼻手术的个体(患者)和年龄和性别匹配的健康志愿者(对照)被纳入这项前瞻性病例对照研究。要确定蠕形螨密度,使用标准浅表皮肤活检方法从患者和对照组的颌骨和鼻部区域收集样本。
    共有50名隆鼻患者和50名健康对照者参加了这项研究。鼻整形患者的鼻部蠕形螨密度明显较高(p=0.0001)。此外,与对照组相比,隆鼻患者的干燥和脓疱的频率显着升高(分别为p=0.046和p=0.001)。
    手术隆鼻术可能是引起痴呆的危险因素,经过适当的诊断和治疗,患者将在手术后更快地康复。
    UNASSIGNED: Human Demodex mites are parasites that live in the pilosebaceous unit and can cause demodicosis. While demodicosis may occur as a primary skin disease, it may also result from immunosuppression and topical or systemic immunosuppressive therapies. Surgical rhinoplasty is one of the most commonly performed cosmetic procedures, and it is the cause of a variety of cutaneous complications, particularly acne, as it affects the skin\'s adnexal structures. Thus, this study aimed to investigate whether the cutaneous changes in surgical rhinoplasty patients render them vulnerable to Demodex infestation.
    UNASSIGNED: Individuals who had undergone rhinoplasty (patients) and age- and sex-matched healthy volunteers (controls) were included in this prospective case-control study. To determine the Demodex density, samples were collected from the malar and nasal regions of both the patients and controls using the standard superficial skin biopsy method.
    UNASSIGNED: A total of 50 rhinoplasty patients and 50 healthy controls were enrolled in the study. The Demodex density on the nose was significantly higher in the rhinoplasty patients (p = 0.0001). Furthermore, the frequency of xerosis and pustules was significantly higher in the rhinoplasty patients compared to the control group (p = 0.046 and p = 0.001, respectively).
    UNASSIGNED: Surgical rhinoplasty may be a risk factor for demodicosis, and patients will recover faster after surgery with proper diagnosis and treatment.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    这项研究解决了在文献中存在127年空白之后,南部塔曼杜瓦(Tamanduatetradactyla)的Psoralgeslibertus螨感染的报告,详细说明临床情况,组织病理学发现,和通过形态学识别螨。这项研究扩大了我们对螨栖息地的理解,强调在管理自由放养和圈养动物的寄生虫健康方面的挑战。它强调了持续监测对保护和公共卫生的重要性,包括潜在的人畜共患问题。一个多世纪后,在T.tetradactyla中发表的P.libertus报告强调了在这种哺乳动物物种中有关螨虫诱导的mange的出版物的稀缺性。调查潜在的自由假单胞菌对tamanduas的影响需要进一步的研究,特别是关于致病性,代理人流行病学,和主机互动。这项研究增强了我们对寄生虫-宿主相互作用及其与野生动物保护的相关性的理解。
    This study addresses the report of Psoralges libertus mite infestations in Southern Tamandua (Tamandua tetradactyla) after a 127-year gap in the literature, detailing clinical conditions, histopathological findings, and mite identification via morphology. The research broadens our understanding of mite habitats, highlighting challenges in managing parasitic health in free-ranging and captive animals. It underscores the importance of ongoing surveillance for conservation and public health, including potential zoonotic concerns. A P. libertus report in T. tetradactyla after over a century highlights the scarcity of publications on mite-induced mange in this mammalian species. Investigating potential P. libertus\' impacts on tamanduas\' well-being necessitates further research, particularly regarding pathogenicity, agent epidemiology, and host interaction. This study enhances our comprehension of parasite-host interactions and their relevance to wildlife conservation.
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  • 文章类型: Journal Article
    背景:人类蠕形螨,毛囊蠕形螨和短蠕形螨,是驻留在毛囊皮脂腺的微生物,通常不会引起症状。在先前的研究中,光疗已与去神器病联系在一起。我们的目的是确定在20次光疗后,蠕形螨的频率和蠕形螨密度是否增加。
    方法:对32名接受窄带紫外线B或紫外线A-1治疗的参与者进行了病例对照研究。在光疗之前和之后进行标准化的皮肤表面活检以评估蠕形螨密度。在光疗之前评估蠕形螨相关皮肤状况的存在。进行统计分析以比较基线和第20次光疗之间的蠕形螨密度和蠕形螨病的患病率。
    结果:20次光疗后,蠕形螨密度没有明显变化。治疗前平均蠕形螨密度为2.75±4.48(/cm2),治疗后,为2.85±4.81(/cm2),差异无统计学意义(P=0.879)。治疗前至少有一个面部区域的痴呆患者比例为28.1%(9/32),治疗后,它是31.3%(10/32),差异无统计学意义(P=1.00)。
    结论:我们的发现与先前的研究相矛盾,先前的研究表明光疗后蠕形螨密度和蠕形螨病患病率增加。先前研究的数据因其选定的样本而存在争议,设计,以及关于光疗-免疫抑制-蠕形螨关系的解释。为了更好地了解光疗与去生物病之间的关系,有必要对均匀样品进行大规模的纵向研究。
    BACKGROUND: Human Demodex mites, Demodex folliculorum and Demodex brevis, are microorganisms that reside in the pilosebaceous units, usually without causing symptoms. Phototherapy has been linked to demodicosis in previous studies. We aimed to determine whether there was an increase in the frequency of demodicosis and Demodex density after 20 phototherapy sessions.
    METHODS: A case-control study was conducted with 32 participants who received narrowband ultraviolet B or ultraviolet A-1 therapy for various dermatological indications. Standardized skin surface biopsies were performed before and after phototherapy to assess Demodex density. The presence of Demodex-related skin conditions was assessed before phototherapy. A statistical analysis was performed to compare the Demodex densities and prevalence of demodicosis between the baseline and 20th session of phototherapy.
    RESULTS: No significant change was observed in Demodex density after 20 sessions of phototherapy. The average Demodex density before treatment was 2.75 ± 4.48 (/cm2 ), and after treatment, it was 2.85 ± 4.81 (/cm2 ), indicating no significant difference (P = 0.879). The percentage of patients with demodicosis in at least one region of the face was 28.1% (9/32) before treatment, and after treatment, it was 31.3% (10/32), with no significant difference (P = 1.00).
    CONCLUSIONS: Our findings contradict previous studies that suggested an increased Demodex density and demodicosis prevalence after phototherapy. The data from previous studies are open to debate due to their selected samples, designs, and interpretations regarding the phototherapy-immunosuppression-Demodex relationship. Larger-scale longitudinal studies conducted on a homogeneous sample are warranted to better understand the relationship between phototherapy and demodicosis.
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  • 文章类型: Case Reports
    Straelensia cynotis is a trombidioid mite that causes painful, usually nonpruritic nodular dermatitis mainly in the dorsal region of dogs. This case report describes the first observation of feline straelensiosis in Europe with clinicopathological findings. Molecular characterisation of the parasite was performed and compared with mites collected from dogs.
    Straelensia cynotis est un acarien trombidioïde qui provoque une dermatite nodulaire douloureuse, généralement non prurigineuse, principalement dans la région dorsale des chiens. Ce cas constitue la première observation de straelensiose féline en Europe avec des données clinicopathologiques. L’identification moléculaire du parasite a été réalisée et comparée à celle d’acariens prélevés sur des chiens.
    Straelensia cynotis es un ácaro trombidioide que causa dermatitis nodular dolorosa, generalmente no pruriginosa, principalmente en la región dorsal de los perros. Este informe de caso describe la primera observación de estraelensiosis felina en Europa con hallazgos clínico-patológicos. Se realizó la caracterización molecular del parásito y se comparó con ácaros recolectados de perros.
    Strelensia cynotis ist eine Milbe der Gattung Trombidium, die eine schmerzhafte, generell nicht juckende knotige Dermatitis, hauptsächlich in der dorsalen Region der Hunde, verursacht. Dieser Fallbericht beschreibt die erste Beobachtung und die klinisch-pathologischen Befunde einer Straelensiose bei einer Katze in Europa. Eine molekulare Charakterisierung des Parasiten wurde durchgeführt und mit den Milben, die bei Hunden gefunden werden, verglichen.
    Straelensia cynotisは、主にイヌの背部に疼痛を伴う、通常非掻痒性の結節性皮膚炎を引き起こすtrombidioidダニである。本症例報告は、臨床病理学的所見とともに、ヨーロッパで初めて観察されたネコのstraelensiosisについて述べたものである。寄生虫の分子学的特性解析を行い、イヌから採取したダニと比較した。.
    斯特伦西亚螨是一种恙螨科螨虫,主要在犬背部引起疼痛的、通常是非瘙痒的结节性皮炎。本病例报告描述了在欧洲首次观察到的,包括临床病理学发现的猫斯特伦西亚恙螨病。对寄生虫进行了分子特性鉴定,并与从犬身上采集的螨虫进行比较。.
    Straelensia cynotis é um ácaro trombiculídeo que causa dermatite nodular dolorosa e geralmente não pruriginosa principalmente na região dorsal de cães. Este relato de caso descreve a primeira observação de stralensiose felina na Europa com achados clinicopatológicos. A caracterização molecular do parasita foi realizada e comparada com ácaros coletados de cães.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    毛囊蠕形螨是一种共生螨,栖息在皮肤毛囊皮脂腺毛囊的孔中。这些生物的过度生长会导致蠕形螨毛囊炎,通常表现为丘疹和脓疱,主要累及太阳穴,脸颊,偶尔还有胸部。我们介绍了一名51岁的女性,患有医源性蠕形螨毛囊炎,继发于免疫抑制治疗的自身免疫性结缔组织病。皮肤活检的组织病理学检查,显示了毛囊性蠕形螨,证实了诊断。用口服伊维菌素和局部甲硝唑凝胶治疗喷发,患者的免疫抑制方案减少,导致6周内的爆发明显改善,并且她的潜在自身免疫性疾病没有恶化。该病例强调了在免疫抑制治疗的背景下,在鉴别诊断新发皮疹时考虑蠕形螨毛囊炎的重要性。
    Demodex folliculorum is a commensal mite that inhabits the orifices of cutaneous pilosebaceous follicles. Overgrowth of these organisms can lead to Demodex folliculitis, which typically presents as papules and pustules predominantly involving the temples, cheeks, and occasionally the chest. We present a 51-year-old woman with iatrogenic Demodex folliculitis secondary to immunosuppressive treatment for an autoimmune connective tissue disease. Histopathological exam of a skin biopsy, which revealed follicular Demodex mites, confirmed the diagnosis. The eruption was treated with oral ivermectin and topical metronidazole gel, and the patient\'s immunosuppressive regimen was decreased, resulting in marked improvement in the eruption within 6 weeks and no worsening of her underlying autoimmune disorder. This case emphasizes the importance of considering Demodex folliculitis in the differential diagnosis of a new onset rash in the context of immunosuppressive treatment.
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