■调查济南市某三甲医院(基层医院)医务人员和体检人群甲状腺结节的患病情况并分析其影响因素。
■共筛选两组5812例。采用t检验和χ2检验分析甲状腺结节患病率的差异。采用多因素Logistic回归分析探讨影响因素。
■医务人员的平均年龄为(36.20±9.11)岁,总患病率为48.5%。医疗保健人群的平均年龄为(57.89±12.51)岁,总患病率为63.9%,两组间差异有统计学意义(均P<0.001)。对两组的分层分析显示,患病率随年龄增长而增加,各年龄段医务人员的患病率均高于50岁以下的健康人群。多因素Logistic回归分析显示,女性性别(OR=1.646,95%CI:1.315-2.060),年龄较大(OR=1.384,95%CI:1.265-1.514),高BMI(OR=1.199,95%CI:1.065-1.350)是医务人员患病的危险因素。在健康人群中,女性(OR=0.799,95%CI:0.644-0.992)和高TSH水平(OR=0.918,95%CI:0.874-0.964)是保护因素,而年龄较大(OR=1.634,95%CI:1.525-1.751)是危险因素。
■两组之间的甲状腺结节患病率存在一定差异。年龄和职业是重要的影响因素。虽然年龄是无法控制的,积极调节职业因素引起的情绪状态,对降低甲状腺结节患病率、减轻社会医疗负担具有重要的临床指导意义。
UNASSIGNED: To investigate the prevalence of thyroid nodules among medical staff and health check-up population in a Level-A hospital (Primary-level hospital) in Jinan City and analyze its influencing factors.
UNASSIGNED: A total of 5812 cases from the two groups were screened. t-test and χ2 tests were used to analyze the differences in the prevalence of thyroid nodules. Multivariate Logistic regression analysis was used to explore the influencing factors.
UNASSIGNED: The average age of medical staff was (36.20±9.11) years old, and the total prevalence was 48.5%. The average age of the healthcare population was (57.89±12.51) years old, and the total prevalence rate was 63.9%, with statistical significance between the two groups (P<0.001 for all). A stratified analysis of the two groups showed that the prevalence increased with age, and the prevalence among medical workers of all ages was higher than that of the health population younger than 50 years of age. Multivariate Logistic regression analysis showed that female sex (OR=1.646,95% CI: 1.315-2.060), older age (OR=1.384,95% CI: 1.265-1.514), and high BMI (OR = 1.199, 95% CI: 1.065-1.350) were risk factors for the disease among medical staff. In the health population, female sex (OR=0.799,95% CI: 0.644-0.992) and high TSH levels (OR = 0.918, 95% CI: 0.874-0.964) were protective factors, while older age (OR=1.634,95% CI: 1.525-1.751) was a risk factor.
UNASSIGNED: There are certain differences in the prevalence of thyroid nodules between the two groups. Age and occupation are important influencing factors. While age is uncontrollable, active regulation of emotional status caused by occupational factors has important clinical guiding significance for reducing the prevalence of thyroid nodules and reducing the social medical burden.