背景:增生性疣状白斑(PVL)是一种多病灶,缓慢发展的病变,抵抗所有类型的治疗,并有很高的恶性转化为口腔鳞状细胞癌的倾向。缺乏对口腔白色病变的认识和认识使其难以诊断。除了稀有,PVL明显具有侵略性,所以临床医生需要注意这一点。因此,建议尽早诊断并完全切除该病变。我们报告此病例是为了呈现PVL的典型临床和组织学特征,以便使临床医生敏感。
方法:一名61岁女性因反复无痛就诊,2个月前舌头上的白色斑点,与口咽干燥有关。
方法:本病例符合诊断PVL的主要和次要标准。
方法:对病灶进行切除活检以检查是否存在发育不良,由于病变持续存在。通过单个中断的缝线实现止血。
结果:自切除1年随访以来未观察到复发。
结论:关键特征是早期发现,正是在PVL的情况下,这对于更好的治疗结果至关重要,救生,提高生活质量。为了检测和治疗任何潜在的疾病,临床医生应认真检查口腔,患者必须意识到并告知定期筛查的重要性。这种病变对目前可用的治疗方式有抵抗力;因此,具有自由手术切缘的全切除与终身随访相结合是至关重要的.
BACKGROUND: Proliferative verrucous leukoplakia (PVL) is a multifocal, slowly evolving lesion that resists all types of treatment and has a high propensity for malignant transformation into oral squamous cell carcinoma. Lack of awareness and acquaintance with white lesions of the oral cavity makes it difficult to diagnose. Besides being rare, PVL significantly aggressive, so clinicians need to be aware of it carefully. Therefore, it is recommended to have the earliest possible diagnosis and total excision of this lesion. We report this
case to present typical clinical and histologic features of PVL so a For the purpose of sensitizing clinician.
METHODS: A 61-year-old female came to the clinic concerning of recurring painless, white patch on the tongue 2 months ago, associated with oropharyngeal dryness.
METHODS: This
case satisfies these major and minor criteria to diagnosed PVL.
METHODS: An excisional biopsy of the lesion was done to check for the presence of dysplasia, as lesions were persisting. Hemostasis was achieved with single interrupted sutures.
RESULTS: no recurrence has been observed since excisional 1 year follow-up.
CONCLUSIONS: The key feature is early detection, precisely in cases of PVL it is critical for better treatment outcomes, lifesaving, quality-of-life enhancement. To detect and treat any potential pathologies, clinicians should meticulously examine the oral cavity and patients have to be aware and informed of the importance of regular screenings. This lesion is resistant to the presently available treatment modalities; therefore, total excision with free surgical margins is critical combined with a lifelong follow-up.