India

印度
  • 文章类型: Journal Article
    背景:糖尿病(DM)和抑郁症是全球主要的公共卫生问题。社区环境中很少报道常见的精神障碍(CMD),包括抑郁症和焦虑症与DM的联系。
    目的:本研究旨在研究居住在印度北部农村地区的成年人口(>30岁)中CMD与DM之间的关联。
    方法:在哈里亚纳邦Faridabad区Ballabgarh街区的28个村庄进行了基于社区的病例对照研究。从社区招募患有至少1年糖尿病的病例(糖尿病)。从同一社区中选择年龄和性别匹配的两个邻居对照。使用糖化血红蛋白确认糖尿病状态。使用PRIME-MD印地语版本对抑郁症和焦虑症等CMD进行了筛查。采用条件logistic回归分析糖尿病与CMDs的关系。
    结果:共211例(糖尿病)和273例对照(非糖尿病)进行了研究,其中173例和175例对照进行分析。病例和对照在年龄方面具有可比性,性别,和社会经济地位。与对照组相比,在病例中发现的CMD更多(67.5%vs.37.5%)(P<0.001)。在条件Logistic回归分析中,CMD在糖尿病病例中显著较高(校正比值比-3.2,95%置信区间:1.9-5.2)。
    结论:来自这项基于人群的研究的CMD和DM共存的有力证据表明,印度有必要将CMD管理纳入糖尿病控制计划。
    BACKGROUND: Diabetes mellitus (DM) and depression are major public health problems globally. Evidence of linkage of common mental disorders (CMDs) including depression and anxiety disorders with DM is sparsely reported from community-based settings.
    OBJECTIVE: The present study aimed to study the association between CMDs and DM among adult population (>30 years) residing in a rural area of North India.
    METHODS: A community-based case-control study was conducted in 28 villages of Ballabgarh block of Faridabad district of Haryana. Cases (diabetes) were recruited from the community with at least 1 year of diabetes. Age- and sex-matched two neighborhood controls were selected from the same community. Diabetic status was confirmed using glycated hemoglobin. CMDs such as depression and anxiety disorders were screened using PRIME-MD Hindi version. Conditional logistic regression was used to study the relationship between diabetes and CMDs.
    RESULTS: Total 211 cases (diabetic) and 273 controls (nondiabetic) were approached for the study, of which 173 cases and 175 controls were analyzed. Cases and controls were comparable with respect to age, sex, and socioeconomic status. CMDs were found more among cases as compared to controls (67.5% vs. 37.5%) (P < 0.001). On conditional logistic regression analysis, CMDs were significantly higher among diabetes cases (adjusted odds ratio - 3.2, 95% confidence interval: 1.9-5.2).
    CONCLUSIONS: Strong evidence of coexistence of CMDs and DM from this population-based study necessitates the need of incorporation of management of CMDs into diabetes control program in India.
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  • 文章类型: Journal Article
    像印度这样的发展中国家正在迅速从传统能源向可持续能源过渡,由于需求的增加和化石燃料的枯竭。并网光伏(PV)系统吸引了许多投资者,组织,和部署机构。本文研究并比较了安装在教育机构的三个52kW光伏电站的性能评估,SRMIST(SRM科学技术研究所),在泰米尔纳德邦,印度。该站点的年平均温度为28.5°C,全球平均水平辐射为160kWh/m2/m。利用太阳辐射获得了52千瓦发电厂的预测模型,温度,和风速。使用Minitab16.2.1软件推导了基于线性回归模型的预测方程,并将结果与2020年从三个52千瓦电厂获得的实时交流能量产量进行比较。此外,这个52千瓦的工厂是使用PVsystV7.1.8版本软件设计的。将模拟结果与2020年工厂的能源产量进行比较,以确定工厂性能的不足。通过从PVsyst软件获得损失图,对工厂进行损失分析。本研究还提出了一种方法来研究委托光伏电站的性能,并确定直接和扩散太阳辐射等变量之间的相互作用,空气温度,和风速,用于预测每小时产生的功率。本文将激励研究人员使用现代技术工具分析已安装的发电厂。
    Developing countries like India are rapidly transitioning from traditional energy sources to sustainable energy sources, due to the increase in demand and the depletion of fossil fuels. Grid-connected photovoltaic (PV) systems attract many investors, organizations, and institutions for deployment. This article studies and compares the performance evaluations of three 52-kW PV plants installed at an educational institution, SRMIST (SRM Institute of Science and Technology), in Tamil Nadu, India. This site receives an annual average temperature of 28.5°C and an average global horizontal irradiation of 160 kWh/m2/m. The prediction model for the 52-kW power plant is obtained using solar radiation, temperature, and wind speed. Linear regression model-based prediction equations are derived using the Minitab 16.2.1 software, and the results are compared with the real-time AC energy yield acquired from the three 52-kW plants for the year 2020. Furthermore, this 52-kW plant is designed using PVsyst V7.1.8 version software. The simulation results are compared with the energy yield from the plants in 2020 to identify the shortfall in the plant performance. The loss analysis for the plant is performed by obtaining the loss diagram from the PVsyst software. This study also proposes a methodology to study the commissioned PV plant\'s performance and determine the interaction between variables such as direct and diffused solar radiations, air temperature, and wind speed for forecasting hourly produced power. This article will motivate researchers to analyze installed power plants using modern technical tools.
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  • 文章类型: Journal Article
    在500万个印度泉水系统中,一些被表征为水化学和淡水潜力。本研究的重点是分析水化学,放电,以及冷温泉群和温泉群的饮用水/灌溉水质,即南喀拉拉邦温泉(SKS)和南西高止山脉的达克希纳卡纳达温泉(DKS),印度。目前,考虑了11个来自SKS的弹簧和10个来自DKS的弹簧,其中包括一个温度范围为34至37°C的热弹簧(TS)。研究表明,SKS的冷泉(CS)为Na-Cl型,而DKS中的热水和冷水泉是Na-HCO3和混合水型,分别。两种不同的机制主要定义了弹簧的水化学组成-SKS受降水的影响,而DKS可能是化学风化过程。在比较温泉(TS)的主要离子和饱和指数时,很明显,硅酸盐矿物主要影响水的化学组成。CaCO3-在TS水中过饱和并倾向于沉淀为结垢层。PCA表明,地质因素和人为因素都会影响水化学。与TS相比,WQI将两个集群中的CS分类为“优秀”等级。灌溉水质表明冷泉仅适用于灌溉。此外,从排放中可以明显看出,SKS和DKS都是雨养的。排放监测指定CS可以增加附近地区的饮用水供应,这表明考虑到未来淡水短缺,保护和可持续利用的必要性。
    Out of 5 million Indian spring water systems, a few were characterised for hydrochemistry and freshwater potential. The present study focuses on analysing the hydrochemistry, discharge, and drinking/irrigation water quality of both cold and thermal spring clusters namely Southern Kerala Springs (SKS) and Dakshina Kannada Springs (DKS) of Southern Western Ghats, India. Currently, eleven springs from SKS and ten from DKS including one thermal spring (TS) with temperature ranges from 34 to 37 °C were considered. The study revealed that cold springs (CS) of SKS are Na-Cl type, while the thermal and cold-water springs in DKS are Na-HCO3 and mixing water type, respectively. Two distinct mechanisms predominantly define the hydro-chemical composition of the springs-SKS are influenced by precipitation, whereas DKS is likely by chemical weathering processes. While comparing the major ions and saturation indices of thermal springs (TS), it is evident that silicate minerals predominantly affect the chemical composition of water. CaCO3- is oversaturated in TS water and tends to precipitate as a scale layer. PCA showed that both geogenic and anthropogenic factors influence water chemistry. WQI categorized the CS in both the clusters are in the \"Excellent\" rank as compared to TS. Irrigation water quality signifies that the cold springs are only suitable for irrigation. Moreover, it is evident from the discharge that both SKS and DKS were rainfed in nature. Discharge monitoring designated that the CS could augment drinking water supplies in the nearby regions indicating the necessity of conservation and sustainable use considering future freshwater scarcity.
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  • 文章类型: Journal Article
    背景:结核病(TB)仍然是印度的重大公共卫生负担,为2025年设定了消除目标。主动病例发现(ACF)对于提高结核病病例检测率至关重要,尽管缺乏与治疗结果相关的确凿证据.我们的研究旨在调查ACF对古吉拉特邦肺结核患者成功结核病治疗结果的影响。印度,并探讨为什么ACF对这些结果产生积极影响。
    方法:我们在古吉拉特邦进行了回顾性队列分析,印度,包括2019年1月至2020年12月通过ACF确定的1,638例肺结核病例和通过被动病例发现(PCF)确定的80,957例肺结核病例。广义逻辑混合模型比较ACF和PCF组的治疗结果。此外,我们对11名结核病项目工作人员进行了深入访谈,以探讨他们对ACF的看法及其对结核病治疗结局的影响.
    结果:我们的分析显示,与通过PCF确定的患者相比,通过ACF诊断的患者显示出1.4倍的成功治疗结果。项目工作人员强调,ACF提高了病例检出率,并能够及早发现并迅速开始治疗。这种早期干预有助于更快的痰转化,并有助于减少传染期,从而改善治疗结果。功能人员强调,ACF识别出可能错过的结核病例,确保及时和适当的治疗。
    结论:ACF显著改善了古吉拉特邦的结核病治疗结果,印度。混合方法分析表明ACF与成功的结核病治疗之间存在正相关,早期发现和及时开始治疗是关键因素。结核病项目工作人员的见解强调了ACF在确保及时诊断和治疗方面的重要性,这对于更好的治疗结果至关重要。扩大ACF倡议,特别是在难以到达的人群中,可以进一步加强结核病控制工作。未来的研究应集中在优化ACF策略和整合其他干预措施以维持和改善结核病治疗结果。
    BACKGROUND: Tuberculosis (TB) remains a significant public health burden in India, with elimination targets set for 2025. Active case finding (ACF) is crucial for improving TB case detection rates, although conclusive evidence of its association with treatment outcomes is lacking. Our study aims to investigate the impact of ACF on successful TB treatment outcomes among pulmonary TB patients in Gujarat, India, and explore why ACF positively impacts these outcomes.
    METHODS: We conducted a retrospective cohort analysis in Gujarat, India, including 1,638 pulmonary TB cases identified through ACF and 80,957 cases through passive case finding (PCF) from January 2019 to December 2020. Generalized logistic mixed-model compared treatment outcomes between the ACF and PCF groups. Additionally, in-depth interviews were conducted with 11 TB program functionaries to explore their perceptions of ACF and its impact on TB treatment outcomes.
    RESULTS: Our analysis revealed that patients diagnosed through ACF exhibited 1.4 times higher odds of successful treatment outcomes compared to those identified through PCF. Program functionaries emphasized that ACF enhances case detection rates and enables early detection and prompt treatment initiation. This early intervention facilitates faster sputum conversion and helps reduce the infectious period, thereby improving treatment outcomes. Functionaries highlighted that ACF identifies TB cases that might otherwise be missed, ensuring timely and appropriate treatment.
    CONCLUSIONS: ACF significantly improves TB treatment outcomes in Gujarat, India. The mixed-methods analysis demonstrates a positive association between ACF and successful TB treatment, with early detection and prompt treatment initiation being key factors. Insights from TB program functionaries underscore the importance of ACF in ensuring timely diagnosis and treatment, which are critical for better treatment outcomes. Expanding ACF initiatives, especially among hard-to-reach populations, can further enhance TB control efforts. Future research should focus on optimizing ACF strategies and integrating additional interventions to sustain and improve TB treatment outcomes.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    背景:石油行业的工作场所事故会对人们造成灾难性的损害,property,和环境。该领域的早期研究表明,大多数事故报告信息以非结构化文本格式提供。事故数据分析的常规技术耗时且严重依赖专家的学科知识,经验,和判断。需要开发基于机器学习的决策支持系统,以分析由于缺乏适当的方法而经常被忽视的大量非结构化文本数据。
    方法:为了解决文献中的这一差距,我们提出了一种混合方法,该方法使用改进的文本挖掘技术,并结合非偏见群体决策框架,将风险因素的客观权重(基于文本挖掘)和主观权重(基于专家意见)的输出进行优先级排序。基于语境词嵌入模型和术语频率,我们提取了5个重要的危险因素集群,包括32个以上的危险子因素.联系了石油行业的异质专家和员工小组,以获取他们对提取的风险因素的意见,并使用最佳-最差的方法将他们的意见转换为权重。
    结论:我们提出的框架的适用性是在根据印度石油工业发布的事故数据汇编的数据上进行的测试。我们的框架可以扩展到任何行业的事故数据,减少分析时间,提高风险因素分类和优先排序的准确性。
    BACKGROUND: Workplace accidents in the petroleum industry can cause catastrophic damage to people, property, and the environment. Earlier studies in this domain indicate that the majority of the accident report information is available in unstructured text format. Conventional techniques for the analysis of accident data are time-consuming and heavily dependent on experts\' subject knowledge, experience, and judgment. There is a need to develop a machine learning-based decision support system to analyze the vast amounts of unstructured text data that are frequently overlooked due to a lack of appropriate methodology.
    METHODS: To address this gap in the literature, we propose a hybrid methodology that uses improved text-mining techniques combined with an un-bias group decision-making framework to combine the output of objective weights (based on text mining) and subjective weights (based on expert opinion) of risk factors to prioritize them. Based on the contextual word embedding models and term frequencies, we extracted five important clusters of risk factors comprising more than 32 risk sub-factors. A heterogeneous group of experts and employees in the petroleum industry were contacted to obtain their opinions on the extracted risk factors, and the best-worst method was used to convert their opinions to weights.
    CONCLUSIONS: The applicability of our proposed framework was tested on the data compiled from the accident data released by the petroleum industries in India. Our framework can be extended to accident data from any industry, to reduce analysis time and improve the accuracy in classifying and prioritizing risk factors.
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  • 文章类型: Journal Article
    背景:印度的儿童营养不良仍然是世界上最高的。印度南部土著人民的成人饮酒和严重营养不良有所增加。然而,人们对它们之间的联系知之甚少。
    目的:我们旨在评估这种关联,这可以帮助设计更好的干预策略。
    方法:本病例对照观察性研究在印度南部的Nilgiri区进行。病例包括1-5岁中度营养不良的儿童。对照组被定义为相同年龄段的儿童,体重正常。问卷被用来收集人口统计数据,社会经济地位(SES),和父母教育。使用WHO酒精使用障碍鉴定测试(AUDIT)问卷来评估父母的酒精使用情况。卫生保健工作者从社区内部收集数据。
    结果:对照组(n=250)和病例组(n=177)儿童的基线人口统计学相似。两组的父亲年龄和AUDIT评分没有差异。营养不良组的SES较低,而病例中的母亲教育程度明显较低。母亲和父亲的教育与儿童营养不良有关(比值比[OR]:0.728[95%置信区间(CI):0.583-0.903]和OR:0.753[95%CI:0.589-0.957],分别)。在调整协变量后,父亲饮酒与较高的营养不良风险相关(OR:1.56[95%CI:1.00-2.47]),其中SES部分介导。
    结论:父亲饮酒与儿童营养不良有关,部分由较低的SES介导。此外,较低的SES似乎与父亲饮酒密切相关。
    BACKGROUND: Childhood malnutrition in India remains among the highest in the world. Adult alcohol consumption and severe malnutrition have increased among indigenous people in South India. However, the association between them is poorly understood.
    OBJECTIVE: We aimed to evaluate this association, which could help design better intervention strategies.
    METHODS: This case-control observational study was conducted in the Nilgiri district in South India. Cases included children aged 1-5 years with moderate malnutrition. Controls were defined as children in the same age group with normal weight-for-age. A questionnaire was used to collect data on demographics, socioeconomic status (SES), and parental education. The WHO Alcohol Use Disorders Identification Test (AUDIT) questionnaire was used to estimate parental alcohol use. Health-care workers collected data from within the community.
    RESULTS: The baseline demographics of the children in the control (n = 250) and case groups (n = 177) were similar. Paternal age and AUDIT scores were not different in the two groups. SES was lower in the malnourished group, while maternal education among cases was significantly lower. Maternal and paternal education were associated with childhood malnutrition (odds ratio [OR]: 0.728 [95% confidence interval (CI): 0.583-0.903] and OR: 0.753 [95% CI: 0.589-0.957], respectively). After adjustment for covariates, paternal alcohol use was associated with a higher risk of malnutrition (OR: 1.56 [95% CI: 1.00-2.47]), which SES partly mediated.
    CONCLUSIONS: Paternal alcohol consumption is associated with childhood malnutrition, partially mediated by lower SES. Furthermore, lower SES appeared to be strongly associated with paternal alcohol consumption.
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  • 文章类型: Case Reports
    视神经神经鞘瘤是文献中描述的非常罕见的肿瘤。这是由于视神经被少突胶质细胞髓鞘化的事实。神经鞘瘤是周围神经系统的肿瘤,因此视神经神经鞘瘤是一种罕见的现象。一名34岁的患者在门诊部就诊,抱怨过去一年左眼(LE)逐渐无痛突出。没有视力减退的历史。在检查中,双眼视力为6/6,双眼眼前段检查正常,学生是中心的,圆形,对光有反应.在非接触式眼压计上测量眼压,并在正常范围内。双眼视神经盘,眼底,视野正常.检查时,在LE中注意到轴向突出。右眼中的下垂测量值(在Hertel突眼仪上)为17mm,左眼为21mm。在没有对比的情况下对眼眶进行了MRI检查,显示出清晰的,左眼眶内间隙视神经软组织病变。通过外侧眼眶切开术进行肿瘤的手术切除,并全部切除肿瘤。肿块的组织病理学检查显示良性梭形细胞肿瘤,提示神经鞘瘤。术后,凋亡得到解决,右眼和左眼均为17毫米(在Hertel眼球上),LE的视力保持不变(6/6)。术后,眼压(非接触式眼压计)在正常范围内,和视盘,眼底,视野正常.
    Optic nerve schwannoma is a very rarely occurring tumor described in the literature. It is due to the fact that the optic nerve is myelinated by oligodendrocytes. Schwannomas are tumors of the peripheral nervous system, hence optic nerve schwannoma is a rare phenomenon. A 34-year-old patient presented in the outpatient department with complaints of gradual painless protrusion of the left eye (LE) for the past one year. There was no history of diminution of vision. On examination, vision in both eyes was 6/6, anterior segment examination in both eyes was normal, and pupils were central, circular, and reacting to light. Intraocular pressure was measured on a noncontact tonometer and was within normal range. Both eyes\' optic disc, fundus, and visual fields were normal. On inspection, axial proptosis was noted in the LE. Proptosis measurement (on Hertel exophthalmometer) in the right eye was 17 mm and in the left eye was 21 mm. MRI of the orbit without contrast was done and showed a well-defined, soft tissue lesion of the optic nerve in the intraconal compartment of the left orbit. Surgical excision of the tumor was done by lateral orbitotomy approach and the tumor was removed in total. Histopathological examination of the mass revealed a benign spindle cell neoplasm suggestive of schwannoma. Postoperatively, proptosis was resolved, 17 mm both in the right and left eye (on Hertel exophthalmometer), and vision in LE remained unchanged (6/6). Postoperatively, intraocular pressure (on noncontact tonometer) was within normal range, and the optic disc, fundus, and visual fields were normal.
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  • 文章类型: Case Reports
    肠道热是由肠道侵入性引起的全身性细菌感染,革兰氏阴性杆菌,命名为伤寒沙门氏菌和伤寒沙门氏菌。它表现出狂热的发烧,头痛,萎靡不振,排便习惯改变,和腹痛。诊断通常通过血培养证实。肠热的胃肠道并发症包括肠出血,肠穿孔,胰腺炎,和胆囊炎.我们遇到一例下消化道出血(便血)作为肠热的并发症。一名35岁的男性患者被送往AsterCMI医院,印度,与干咳相关的2周间歇性发热,食欲不振,腹痛,和全身无力。入院四天后,他经历了三次下消化道出血。在体检时,他血流动力学稳定,发高烧,轻度肝肿大,脾肿大,和下腹部压痛。血培养培养伤寒沙门氏菌。腹部超声显示回肠结肠增厚伴肠系膜淋巴结肿大。腹部计算机断层扫描显示肠系膜淋巴结肿大,周围有脂肪束。结肠镜检查显示多个浅层,打孔,和点状回肠结肠溃疡性病变,盲肠溃疡有活动性出血的柱头。结肠镜引导活检提示多灶性活动性结肠炎有利于感染性病因。诊断为血培养证实的肠溃疡。他每天两次静脉注射头孢曲松1g治疗10天,并用静脉输液补水。在出血性溃疡部位注射肾上腺素,止血是安全的。其他额外的药物是退烧药,抗催吐剂,多种维生素,和质子泵抑制剂.入院第三天无发热,住院10天后出院。一周后,他被任命为随访诊所。在第一次随访诊所访问的当天,他完全健康,并计划恢复他的职责。在大多数发展中国家,肠道热仍然是一个常见的公共卫生问题。早期怀疑和及时使用适当的抗生素对于减少肠道热的全身和局部并发症至关重要。由于肠道热的胃肠道并发症在抗生素时代很少遇到,临床医生应认识到肠溃疡是下消化道出血的一个原因.
    Enteric fever is a systemic bacterial infection caused by enteroinvasive, gram-negative bacilli, named Salmonella enterica serovar typhi and Salmonella enterica serovar paratyphi. It presents with hectic fever, headache, malaise, bowel habit changes, and abdominal pain. Diagnosis is usually confirmed by blood culture. Gastrointestinal complications of enteric fever include intestinal bleeding, bowel perforation, pancreatitis, and cholecystitis. We encountered a case of lower gastrointestinal bleeding (hematochezia) as a complication of enteric fever. A 35-year-old male patient presented to Aster CMI hospital, India, with an intermittent fever of 2-week duration associated with dry cough, loss of appetite, abdominal pain, and generalized body weakness. Four days after admission, he experienced three episodes of lower gastrointestinal bleeding. Upon physical examination, he was hemodynamically stable and had a high-grade fever, mild hepatomegaly, tipped splenomegaly, and lower abdominal tenderness. Blood culture grew Salmonella typhi. Abdominal ultrasound showed ileocolonic thickening with enlarged mesenteric lymph nodes. Abdominal computed tomography scan displayed enlarged mesenteric lymph nodes with surrounding fat strands. A colonoscopy revealed multiple shallow, punched-out, and punctate ileocolonic ulcerative lesions, with stigmata of active bleeding at caecal ulcers. Colonoscopy-guided biopsy suggested multifocal active colitis favoring infective etiology. Diagnosis of blood culture-confirmed enteric ulcer was made. He was treated with ceftriaxone 1 g iv twice daily for 10 days and rehydrated with intravenous fluids. Adrenaline injection was done at the site of bleeding ulcers, and hemostasis was secured. Other additional medications were antipyretics, anti-emetics, multivitamins, and proton pump inhibitors. He was fever-free on the third day of admission and discharged after 10 days of hospital stay. He was appointed to follow-up clinic after a week. He was completely healthy on the day of the first follow-up clinic visit and planned to resume his duties. Enteric fever remains a common public health problem in most developing countries. Early suspicion and prompt institution of appropriate antibiotics are crucial in the reduction of systemic and local complications of enteric fever. Since gastrointestinal complications of enteric fever are less often encountered in the antibiotic era, clinicians should be cognizant of an enteric ulcer as a cause of lower gastrointestinal bleeding.
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