背景:马拉喀什是一种非常罕见的良性肉芽肿性疾病,可以侵入多个器官系统,通常与细菌感染和免疫力弱有关。它很少发生在喉部,一旦发生这种情况,病人会抱怨咳嗽,声音嘶哑,吞咽困难,甚至呼吸困难.
方法:我们报告了1例喉真斑病。患者主诉声音嘶哑和咳嗽。她的病变位于右侧假声带。本文从文献中整理了6例喉部malacoplakia病例报告,并与该病例报告进行了整合。
结果:切除肿瘤后,患者咳嗽的症状,声音嘶哑和吞咽困难得到改善,1年随访期间无复发.术后病理诊断为真斑病。我们发现,软化斑更常见于声门上区,我们推测喉相关淋巴组织(LALT)可能与喉真斑病有关。手术治疗喉部软化斑效果满意。
结论:喉部真斑病少见。细菌感染,免疫缺陷,LALT的分布可能与真斑病的发病机制及声门上定位有关。症状与肿块的位置和大小有关,可能是严重和致命的。手术是保留喉功效和低复发率的重要医治办法。
BACKGROUND: Malakoplakia is a very rare benign granulomatous disease, which can invade multiple organ systems, and is often related to bacterial infection and weak immunity. It is rarely occurred in the larynx, once this happens, the patient would complain of cough, hoarseness, dysphagia, and even dyspnea.
METHODS: We reported a
case of malakoplakia of larynx. The patient complained of hoarseness and cough. Her lesion was located in the right false vocal cord. six
case reports of malacoplakia in larynx were compiled from the literature and integrated with this
case report.
RESULTS: After excising the tumor, the symptoms of the patient with cough, hoarseness and dysphagia were improved, and there was no recurrence during 1-year follow-up. The postoperative pathological diagnosis is malakoplakia. We found that malacoplakia is more commonly located in the supraglottic region, and we speculate that there may be a relationship between larynx-associated lymphoid tissue (LALT) and laryngeal malakoplakia. The effect of surgical treatment for laryngeal malacoplakia is satisfactory.
CONCLUSIONS: Malakoplakia of the larynx is rare. Bacterial infection, immune deficiency, and the distribution of LALT may be related to the pathogenesis and supraglottic localization of malakoplakia. The symptoms are related to the location and size of the mass and may be serious and fatal. Surgery is an important treatment for preserving laryngeal function and low recurrence rate.