UNASSIGNED:特发性颅内高压(IIH)在文献中有很好的描述。然而,来自印度次大陆的关于临床和放射学特征的大型研究仍然很少。
UNASSIGNED:分析IIH的临床和放射学特征以及各种临床和放射学参数与乳头水肿和CSF开放压力的相关性。
未经评估:基于医院的观察,描述性研究。
UNASSIGNED:本研究分析了神经内科(2014年1月至2018年12月)收治的122例患者的详细病史,临床检查,和神经成像。进行脑脊液测压和常规脑脊液分析。所有参与者均符合修改后的Dandy标准。排除继发性原因升高的ICP和原发性眼部病理的患者。
未经评估:描述性统计和卡方检验。
未经证实:122例86例(70.49%)为女性。平均年龄为33岁。肥胖62例(50.82%)。头痛是最常见的症状(114/122;93.44%)。双侧乳头水肿114例(93.44%)。较高等级的乳头水肿与较高的CSF开放压力有关。空蝶鞍是最常见的放射学发现(100/122;81.97%)。除空蝶鞍外,所有放射学发现均与较高的CSF开放压力相关。
未经评估:IIH通常影响育龄组肥胖女性。然而,在非肥胖和男性中并不少见。肥胖可能不是印度次大陆IIH发展的主要危险因素。BMI正常和男性具有颅内压升高和神经影像学正常的临床特征的病例也应进行IIH评估。在MRI上患有难治性头痛和空蝶鞍的病例应进行IIH评估。
UNASSIGNED: Idiopathic intracranial hypertension (
IIH) is well-described entity in literature. However, large studies on clinical and radiological profile are still very few from the Indian subcontinent.
UNASSIGNED: To analyze the clinical and radiological profile of IIH and correlation of various clinical and radiological parameters with papilledema and CSF opening pressure.
UNASSIGNED: Hospital-based observational, descriptive
study.
UNASSIGNED: This
study analyzed 122 patients admitted in the department of Neurology (from January 2014 to December 2018) for detailed history, clinical examination, and neuroimaging. CSF manometry and routine CSF analysis were done. All participants met the modified Dandy criteria. Patients with secondary causes of raised ICP and primary ocular pathology were excluded.
UNASSIGNED: Descriptive statistics and Chi-square test.
UNASSIGNED: Among 122 cases 86 (70.49%) were females. The mean age was 33 years. 62 (50.82%) cases were obese. Headache was the most common symptom (114/122; 93.44%). Bilateral papilledema was noted in 114 (93.44%) cases. Higher grades of papilledema had a correlation with higher CSF opening pressure. Empty sella was the most common radiological finding (100/122; 81.97%). All radiological findings except empty sella had a correlation with higher CSF opening pressure.
UNASSIGNED: IIH typically affects obese females of childbearing age group. However, it is not uncommon in the nonobese and male sex. Obesity may not be a dominant risk factor for the development of IIH in the Indian subcontinent. Cases with normal BMI and male sex with clinical features of raised intracranial pressure and normal neuroimaging should also be evaluated for IIH. Cases with refractory headache and empty sella on MRI should be evaluated for
IIH.