Sporotrichosis is a subacute or chronic infectious disease caused by sporothrix. It is mainly caused by Sporothrix inoculation after accidental skin injury during human labor. The clinical manifestations of sporotrichosis are variable, ranging from nodules, plaques, ulcers, verrucous lesions, and subcutaneous masses. Some reports indicate that sporotrichosis can mimic psoriasis-like lesions. We herein report a case of sporotrichosis mimicking rosacea lesions. In addition, the patient had a history of nasal trauma, and we believe that the patient was inoculated with Sporothrix after the nasal skin was damaged during labor activities. The patient was given itraconazole 200 mg orally daily for 3 months, which effectively resolved the rash.

Merkel cell carcinoma (MCC) is a rare primary neuroendocrine skin tumor that presents as a flesh-colored or bluish-red nodule on the face, neck, or head. Long-term ultraviolet radiation exposure and Merkel cell polyomavirus are associated with MCC pathogenesis. We present a case of MCC on the right cheek in a male patient aged 87 years. Our primary goal in presenting the case is to bring MCC, which is a diagnostic challenge, to the notice of dermatologists and oncologists, as early detection and prompt treatment are important. The patient had a significant past medical history, including diabetes mellitus, hypertension, dyslipidemia, stage 3 chronic kidney disease, benign prostatic hyperplasia, chronic hyponatremia, acute pancreatitis, essential thrombocytosis on hydroxyurea, and ischemic heart disease. The patient presented with a mildly swollen right upper lip showing a poorly defined, relatively homogeneous subcutaneous lesion with a history of persistence for 1.5 months. The clinical examination revealed a 5 × 3-cm nodular lesion on the right side of the cheek with swelling of the right upper lip. Immunohistochemistry markers and histopathological features confirmed the diagnosis of MCC. The patient was referred to the oncology department for further management. MCC of the skin is an aggressive lesion with a high risk of metastasis and recurrence, which is more common in immunocompromised people. Prompt management and treatment of MCC is essential because if left untreated, it can spread to other parts of the body and can also metastasize to lymph nodes and other organs. The patient is 87 years old and has a significant past medical history of diabetes mellitus, hypertension, dyslipidemia, chronic kidney disease stage 3, benign prostatic hyperplasia, chronic hyponatremia, acute pancreatitis, essential thrombocytosis on hydroxyurea, and ischemic heart disease. Currently, the patient presented with a mildly swollen right upper lip showing a poorly defined, relatively homogenous subcutaneous lesion with a history of persistence for 1.5 months. The clinical examination revealed a 5x3 cm nodular lesion on the right side of the cheek with swelling of the right upper lip. Immunohistochemistry markers results and histopathological features confirmed the diagnosis of Merkel cell carcinoma. The patient was referred to the oncology department for further management. Merkel cell carcinoma of the skin is an aggressive lesion with a high risk of metastasis and recurrence, which is more common in immunocompromised people. Prompt management and treatment of Merkel cell carcinoma is essential because if left untreated, it can spread to other parts of the body and can also metastasize to lymph nodes and other organs.

Oncocytoma is a benign tumor of the salivary gland. Its incidence is very low and very seldom documen-ted in literature. Clear-cell dominant oncocytoma is even less common. The tumor\'s clinical symptoms and imaging results are nonspecific, so distinguishing other salivary gland tumors (such as oncocytic carcinoma) from clear-cell renal carcinoma is difficult, possibly leading to misdiagnosis and maltreatment. Here, a case of clear-cell dominant oncocytoma was presented, and the relevant literature was evaluated to investigate the diagnosis and management of clear-cell dominant oncocytoma.
腮腺嗜酸细胞腺瘤是一种涎腺良性肿瘤，其发病率低，既往文献少有报道，而以透明细胞为主型的嗜酸细胞腺瘤病例报道更为少见。该肿瘤临床表现及影像学检查无特异性，在诊疗中与涎腺其他肿瘤如嗜酸细胞癌以及转移性肾透明细胞癌鉴别困难，易导致误诊误治。为探讨涎腺透明细胞为主型嗜酸细胞腺瘤的诊断和治疗，提高对该肿瘤的临床病理组织学特征的认识，现报告1例腮腺透明细胞为主型嗜酸细胞腺瘤病例，并对以往相关文献进行回顾复习。.

Endometrial stromal sarcoma (ESS) is an uncommon uterine mesenchymal neoplasm. The primary extra-uterine location of ESS is a very rare occurrence. We present a case of a 39-year-old woman presented with severe abdominal pain, MRI showed bilateral ovarian tumors with heterogeneous intensity on T2-weighted imaging (T2WI) and T1-weighted imaging (T1WI), with restricted diffusion, including hyperintense areas on T1WI, not erased on T1-weighted fat-suppressed imaging, hypointense on T2WI, and not enhanced after contrast. This mass extended to the Douglas and invaded the uterine and the rectum serosa suggesting an underlying endometriosis. No abnormalities were suspected in the endometrium. The exploration revealed a friable mass arising from ovaries associated with nodules in the small intestine and sigmoid. The patient underwent bilateral adnexectomy and the anatomopathological study revealed a low-grade endometrial stromal sarcoma. This is one of the few reports covering the radiological features of low-grade extra-uterine ESS in the ovary which is probably secondary to degeneration of endometriosis with no evidence of primary uterine ESS.

IgG4-related disease (IgG4-RD) is a condition that was first described recently, and is capable of affecting any organ of the body. Diagnosis is based on the correlation of clinical findings with histopathological findings and elevated serum IgG4. Treatment involves corticosteroids and rituximab for the most severe cases. We report the case of a symptomatic patient diagnosed of IgG4-RD whose diagnosed was guided by elevated serum IgG4 levels.

UNASSIGNED: Gorham-Stout disease (GSD) is a rare osteolytic disease with unknown etiology, varied clinical manifestations and unpredictable prognosis. This disease is characterized by progressive massive local osteolysis and resorption caused by intraosseous lymphatic vessel structure and thin-walled vascular proliferation. The diagnosis of GSD has not yet formed a uniform standard, but the combination of clinical manifestations, radiological features and unique histopathological examinations and excluding other diseases contribute to early diagnosis. Although medical therapy, radiotherapy and surgical interventions or combinations have been used for the treatment of GSD, there is currently still no recommended standardized treatment regimen.
UNASSIGNED: This paper presents a case of a previously healthy 70-year-old man presented with a 10-year history of severe right hip pain and progressive walking disorder of the lower limbs. Based on the patient\'s clear clinical presentation, unique radiological features, and histological findings, a diagnosis of GSD was made with the exclusion of other potential diseases. The patient was treated with bisphosphonates to slow the progression of the disease followed by total hip arthroplasty to help restore walking function. At the 3-year follow-up, the patient returned to normal walking and no recurrence was observed.
UNASSIGNED: Bisphosphonates combined with total hip arthroplasty may be an effective method for the treatment of severe GSD in the hip joint.

To describe a rare case of spindle cell tumor in the nasal cavity of a young female, along with its successful surgical management using a low-temperature plasma knife. A 38-year-old female patient presented with a 6-month history of nasal blockage, hyposmia, and local tenderness. The patient denied a history of definite diagnosis or special treatment. A preoperative magnetic resonance imaging scan revealed the size and extent of the tumor in her nasal cavity. She underwent endoscopic surgery for the sinus using a low-temperature plasma knife. The procedure was performed without complications, and her symptoms resolved within 1 month. The postoperative pathology report suggested a spindle cell tumor in her nasal cavity. Nasal spindle cell tumor is rare and usually presents with no specific clinical symptoms, which should be taken into consideration during diagnosis. In this case, we demonstrate that the effectiveness and safety of sinus surgery can be improved and aided by a low-temperature plasma knife and nasal endoscopy.

Kimura\'s disease (KD) is a rare chronic inflammatory or allergic disease. Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign vascular neoplasm. Their relationship has always been debated. This article reports two rare cases, one of each disease. One patient was a 48-year-old female that presented with a mass on her right mandible. She also had oedema erythema and wheals on her lower limbs. She was diagnosed with Kimura\'s disease complicated with chronic urticaria. The second patient was a 23-year-old female that presented with multiple nodules of unequal size on the scalp. She was diagnosed with angiolymphoid hyperplasia with eosinophilia. The first patient recovered after being treated with surgical resection, glucocorticosteroids, cyclophosphamide and radiotherapy. The second patient underwent the first stage of surgical excision and is currently being followed-up. Comparison of the clinical and histopathological features of these two cases supports the theory that KD and ALHE are two separate disease entities.

Neurilemmomas, or called schwannomas, are tumors originating from schwann cells of the nerve sheath.With integrate capsules,the slow growing tumors are presenting benign properties in quite a few clinical cases.Approximately 25%~40% of all schwannomas were reported in the soft tissues of the head and neck. However,as a rare region, schwannomas in oral cavity was only reported less than 1% of all head and neck locations. We contribute the case of a 17 years old girl,who was experiencing progressive odynophagia and dysarthria. The lingual root\'s Neurilemmoma, as the final diagnosis, was confirmed by preoperative laryngendoscopy and histopathological examination. The surgery was conducted by suspension laryngoscope. Completely excised lesion was histopathological identified,which showed strong and diffuse staining with S100.

BACKGROUND: Nodular Fasciitis, also known as infiltrative or pseudosarcomatous fasciitis, is a benign soft tissue tumour of fibroblastic/myofibroblastic differentiation, that was first described in 1955 by Konwaler et al. PRESENTATION OF CASE: This is a case report of a 27-year old male with complaints of a swelling in the right axilla for 2 and ½ years measuring 12 cm × 10 cm. Chest X-Ray was normal. Magnetic Resonance Imaging of the right arm and chest showed an irregular mass in the axilla in the muscular-subcutaneous plane measuring 10.8 cm × 8.8 cm × 12 cm, with no neural involvement. Magnetic Resonance Angiogram showed feeders from the branches of the Right Subclavian and Right Axillary Artery and venous drainage into the Right Subclavian Vein. USG guided biopsy was done which showed benign spindle cell neoplasm. Patient underwent wide local excision under general anesthesia. The specimen was sent for histopathological examination which showed histological and immunohistochemical features in favour of Nodular Fasciitis.
CONCLUSIONS: Most nodular fasciitis lesions are solitary and occur in adults 20-40 years of age. Nodular fasciitis affects both men and women with equal frequency. Differential diagnosis of nodular fasciitis includes, fibrosarcoma, fibroma, fibrous histiocytoma, and desmoids and histopathology and immunohistochemistry play a key role in identifying the condition.
CONCLUSIONS: Owing to the size, location and findings of the Magnetic Resonance Angiogram we initially suspected a Soft Tissue Sarcoma, but to our surprise, on further investigation the mass was revealed to be Nodular Fasciitis.