Histopathological

组织病理学
  • 文章类型: Review
    Oncocytoma is a benign tumor of the salivary gland. Its incidence is very low and very seldom documen-ted in literature. Clear-cell dominant oncocytoma is even less common. The tumor\'s clinical symptoms and imaging results are nonspecific, so distinguishing other salivary gland tumors (such as oncocytic carcinoma) from clear-cell renal carcinoma is difficult, possibly leading to misdiagnosis and maltreatment. Here, a case of clear-cell dominant oncocytoma was presented, and the relevant literature was evaluated to investigate the diagnosis and management of clear-cell dominant oncocytoma.
    腮腺嗜酸细胞腺瘤是一种涎腺良性肿瘤,其发病率低,既往文献少有报道,而以透明细胞为主型的嗜酸细胞腺瘤病例报道更为少见。该肿瘤临床表现及影像学检查无特异性,在诊疗中与涎腺其他肿瘤如嗜酸细胞癌以及转移性肾透明细胞癌鉴别困难,易导致误诊误治。为探讨涎腺透明细胞为主型嗜酸细胞腺瘤的诊断和治疗,提高对该肿瘤的临床病理组织学特征的认识,现报告1例腮腺透明细胞为主型嗜酸细胞腺瘤病例,并对以往相关文献进行回顾复习。.
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  • 文章类型: Case Reports
    Kimura\'s disease (KD) is a rare chronic inflammatory or allergic disease. Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign vascular neoplasm. Their relationship has always been debated. This article reports two rare cases, one of each disease. One patient was a 48-year-old female that presented with a mass on her right mandible. She also had oedema erythema and wheals on her lower limbs. She was diagnosed with Kimura\'s disease complicated with chronic urticaria. The second patient was a 23-year-old female that presented with multiple nodules of unequal size on the scalp. She was diagnosed with angiolymphoid hyperplasia with eosinophilia. The first patient recovered after being treated with surgical resection, glucocorticosteroids, cyclophosphamide and radiotherapy. The second patient underwent the first stage of surgical excision and is currently being followed-up. Comparison of the clinical and histopathological features of these two cases supports the theory that KD and ALHE are two separate disease entities.
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  • 文章类型: Journal Article
    介绍良性胆囊疾病的胆囊切除术可在组织病理学评估期间导致先前未诊断的胆囊癌。尽管对它的有用性存在一些争议,所有胆囊标本的组织病理学评估在大多数医院都很常见。我们针对意外的原发性胆囊癌(UPGC)评估了胆囊切除术后良性胆囊疾病的常规病理结果。方法选取2009年至2013年因胆囊良性疾病行胆囊切除术的患者为研究对象。所有胆囊标本都送到病理科,并详细检查了组织病理学报告。评估人口统计学特征对病理诊断和UPGC患病率的影响。收集了UPGC患者的其他干预措施和术后生存率的数据。结果我们纳入了1,747例患者(平均年龄,48.7±13.6年)。慢性胆囊炎是最常见的诊断(96.3%),并且与女性显着相关(p=0.001)。4例患者有UPGC(0.23%),1例为手术时的T3期,其余3例为T2期。结论胆囊的常规组织病理学检查对于识别需要进一步术后处理的癌症是有价值的。
    Introduction Cholecystectomy for benign gallbladder diseases can lead to previously undiagnosed gallbladder cancer during histopathological evaluation. Despite some controversy over its usefulness, histopathological evaluation of all gallbladder specimens is common in most hospitals. We evaluated the results of routine pathology of the gallbladder after cholecystectomy for benign gallbladder diseases with regard to unexpected primary gallbladder cancer (UPGC). Methods Patients undergoing cholecystectomy because of benign gallbladder diseases between 2009 and 2013 were enrolled in this study. All gallbladder specimens were sent to the pathology department, and histopathological reports were examined in detail. The impact of demographic features on pathological diagnoses and prevalence of UPGC assessed. Data on additional interventions and postoperative survival for patients with UPGC were collected. Results We enrolled 1,747 patients (mean age, 48.7±13.6 years). Chronic cholecystitis was the most common diagnosis (96.3%) and was associated significantly with being female (p=0.001). Four patients had UPGC (0.23%); one was stage T3 at the time of surgery, and the remaining three cases were stage T2. Conclusions Routine histopathological examination of the gallbladder is valuable for identification of cancer that requires further postoperative management.
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