Ganglion cyst

神经节囊肿
  • 文章类型: Journal Article
    背景:硬化疗法在治疗指状黏液囊肿(DMC)的非手术选择中显示出优异的疗效。值得注意的是,先前的研究表明,博来霉素具有更有利的副作用,并且与常规硬化剂具有相似的疗效.
    目的:本研究旨在通过皮质类固醇ILI和手术切除的比较分析,评估博来霉素病灶内注射(ILI)治疗DMC的疗效和安全性。
    方法:我们回顾了电子病历和临床照片。进行电话访谈以进一步调查长期治疗效果,安全,总体治疗满意度。
    结果:10例患者接受了手术切除,13和15例患者接受博来霉素和皮质类固醇ILI,分别。与皮质类固醇ILI相比,手术切除和博来霉素ILI均显示出更好的治疗效果。手术切除和博来霉素ILI之间的治疗效果没有统计学上的显着差异。没有观察到明显的不良反应。在调查中,博来霉素ILI的满意度最高,其次是手术切除和皮质类固醇ILI。
    结论:这项研究表明,博来霉素ILI的治疗效果高于皮质类固醇ILI,略低于手术切除,没有任何副作用。因此,博来霉素ILI是治疗DMC的安全有效的治疗选择。
    BACKGROUND: Sclerotherapy has shown superior efficacy among the nonsurgical options for managing digital mucous cysts (DMC). Notably, previous research has indicated that bleomycin offers a more favorable side-effect profile and similar efficacy to conventional sclerosing agents.
    OBJECTIVE: This study aimed to assess the efficacy and safety of bleomycin intralesional injection (ILI) for treating DMC through a comparative analysis of corticosteroid ILI and surgical excision.
    METHODS: We retrospectively reviewed electronic medical records and clinical photographs. Telephone interviews were conducted to further investigate long-term treatment efficacy, safety, and overall treatment satisfaction.
    RESULTS: Ten patients underwent surgical excision, and 13 and 15 patients received bleomycin and corticosteroid ILI, respectively. Both surgical excision and bleomycin ILI demonstrated superior treatment efficacy compared to corticosteroid ILI. No statistically significant difference in the treatment effectiveness between surgical excision and bleomycin ILI was observed. No significant adverse effects were observed. In the survey, the level of satisfaction was the highest for bleomycin ILI, followed by surgical excision and corticosteroid ILI.
    CONCLUSIONS: This study revealed that bleomycin ILI exhibits a treatment efficacy higher than that of corticosteroid ILI and slightly lower than that of surgical excision, without any side effects. Therefore, bleomycin ILI is a safe and effective therapeutic option for the treatment of DMC.
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  • 文章类型: Journal Article
    前交叉韧带(ACL)是膝关节中常见的损伤韧带。骨隧道加宽是软组织ACL重建和病因后的已知现象,其临床相关性尚未完全阐明。骨传导化合物是为骨形成提供适当支架的生物材料,例如去矿质骨基质。骨诱导材料含有刺激骨谱系细胞和骨生长的生长因子。骨诱导/骨传导(OIC)材料的可能应用是在ACL手术中。我们假设OIC放置在ACL骨隧道中:(1)减少隧道加宽,(2)提高嫁接成熟,(3)减少隧道神经节囊肿的形成。为了检验这个假设,这项研究评估了脱矿质骨基质(DBM)和富血小板血浆(PRP)对隧道加宽的成骨作用,移植物成熟,和神经节囊肿的形成.这是一项随机对照临床试验试点研究。选择进行ACL重建手术的26例患者随机分为OIC组和对照组。通过对两组手术后六个月进行的MRI扫描的定量图像分析,进行了隧道扩展和移植物隧道合并的测量。无患者出现术后不良反应或感染。使用OIC可显着减少隧道加宽(p<0.05)并改善移植物成熟(p<0.05)。与对照组相比,接受OIC治疗的患者的神经节囊肿患病率显着降低(p<0.05)。OIC的使用对减少隧道加宽具有可测量的影响,改善移植物成熟,ACL重建后神经节囊肿大小减小。这项研究探讨了在ACL重建手术中利用生物制剂来最大程度地减少骨隧道的扩大。
    The anterior cruciate ligament (ACL) is a commonly injured ligament in the knee. Bone tunnel widening is a known phenomenon after soft-tissue ACL reconstruction and etiology and the clinical relevance has not been fully elucidated. Osteoconductive compounds are biomaterials providing an appropriate scaffold for bone formation such as a demineralized bone matrix. Osteoinductive materials contain growth factors stimulating bone lineage cells and bone growth. A possible application of osteoinductive/osteoconductive (OIC) material is in ACL surgery. We hypothesized that OIC placed in ACL bone tunnels: (1) reduces tunnel widening, (2) improves graft maturation, and (3) reduces tunnel ganglion cyst formation. To test this hypothesis, this study evaluated the osteogenic effects of demineralized bone matrix (DBM) and platelet-rich plasma (PRP) on tunnel widening, graft maturation, and ganglion cyst formation. This was a randomized controlled clinical trial pilot study. A total of 26 patients that elected to have ACL reconstruction surgery were randomized between the OIC and control group. Measurements of tunnel expansion and graft-tunnel incorporation were conducted via the quantitative image analysis of MRI scans performed at six months after surgery for both groups. No patients had adverse post-operative reactions or infections. The use of OIC significantly reduced tunnel widening (p < 0.05) and improved graft maturation (p < 0.05). Patients treated with OIC had a significantly lower prevalence of ganglion cyst compared to the control group (p < 0.05). The use of OIC has measurable effects on the reduction of tunnel widening, improved graft maturation, and decreased size of ganglion cyst after ACL reconstruction. This study explored the utilization of biologics to minimize bone tunnel widening in ACL reconstruction surgery.
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  • 文章类型: Case Reports
    肌周细胞瘤(MPC)是一种罕见的皮肤和软组织良性肿瘤,属于一系列在组织学上通过其独特的血管周围肌样细胞分化而被识别的肿瘤。这些独特的肿瘤在中年男性中更为普遍,它们更频繁地出现在四肢的皮下组织中。在本文中,据报道,一名59岁的沙特男性患有肌周细胞瘤,出现无痛性小囊肿,累及临床怀疑为神经节囊肿的左踝。手术切除囊肿后,肌周细胞瘤的诊断是根据疾病的组织病理学模式进行的。本文重点介绍了肌周细胞瘤的临床和组织病理学发现,并强调了免疫组织化学和分子检测在最终诊断中的重要性。
    Myopericytoma (MPC) is an uncommon benign neoplasm of the skin and soft tissues belonging to a spectrum of tumors that are histologically recognized by their distinctive perivascular myoid cell differentiation. These distinct tumors are more prevalent among middle-aged males, and they arise more frequently in the subcutaneous tissue of the four extremities. In this paper, myopericytoma is reported in a 59-year-old Saudi male, presented with a painless small cyst involving the left ankle suspected clinically to be a ganglion cyst. Following surgical excision of the cyst, the diagnosis of myopericytoma was made based on the histopathological pattern of the disease. This paper focuses on the clinical and histopathological findings of myopericytoma and emphasizes the importance of immunohistochemistry as well as molecular testing in reaching the final diagnosis.
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  • 文章类型: Journal Article
    UNASSIGNED: Numerous pathological processes involve synovium and periarticular tissues that are characteristic and in some cases specific to a particular disease. Synovial fluid is a thick, stringy fluid found in the cavity of synovial joint. Examination of the synovium plays a key role in the diagnosis of many joint diseases.
    UNASSIGNED: The aim of this study was to study the spectrum of synovial lesions on fine needle aspiration cytology (FNAC) and to compare the cytological diagnosis with histopathological findings.
    UNASSIGNED: This retrospective diagnostic analytical study was carried out in the Department of Pathology. Sixty-six patients with suspected synovial lesions referred from other departments who underwent FNAC during 1 year from January 2017 to December 2017 were included in the study. The slides along with records of the patients were retrieved and findings recorded. Histopathological evaluation was performed wherever possible and compared with cytological diagnosis.
    UNASSIGNED: Non-neoplastic lesions accounted for 80.3% cases followed by benign tumors (15.2%). Ganglion cyst was the commonest non-neoplastic lesion (60.6%, 40/66), while tenosynovial giant cell tumor was the commonest neoplasm (12.1%, 8/66) observed in our study. Solitary case of synovial sarcoma was also observed. Histopathological evaluation was performed in 14 cases and FNAC had overall diagnostic accuracy of 85.7% in diagnosis of these lesions.
    UNASSIGNED: FNAC is a useful tool with high diagnostic accuracy in the evaluation of synovial lesions.
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  • 文章类型: Journal Article
    Background: Despite the role of one\'s hands in human function and quality of life, financial disincentives to perform common hand procedures in patients with government-sponsored insurance plans may lead to longer wait times and decreased access to care. Here, we identify the variations in reimbursement for 4 common hand procedures as a step toward understanding these financial implications to develop safeguards to minimize effects on access to care. Methods: Billing data were collected over a 10-year period for patients undergoing carpal tunnel release (open, Current Procedural Terminology 64721; endoscopic, 29848), cubital tunnel release (64718), ganglion cyst excision (25111), and interposition arthroplasty (25447). Patients were placed into cohorts according to insurance type-private insurance, Medicare, Medicaid, or worker\'s compensation-and these were directly compared. Results: A total of 3489 procedures between 2005 and 2015 were identified in this study (carpal tunnel 65.8%, cubital tunnel 28.7%, ganglion cyst excision 4.1%, and interposition arthroplasty 13.8%). In all, 54.7% of patients had private insurance; 26.3%, Medicare; 10.5%, worker\'s compensation; and 8.5%, Medicaid. Reimbursement, as a percentage of charge, differed significantly by payor type for all cases and by procedure. On average, worker\'s compensation plans reimbursed 65.5% of submitted charges; private insurance, 50.6%; Medicare, 25.1%; and Medicaid, 24.6%. Conclusions: We found that wide variations in reimbursement for common hand procedures exist and may preclude some surgeons from offering certain procedures to a subset of patients. Understanding these discrepancies is a key first step in minimizing a potential care delivery disparity for this patient population.
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