PDF(Pubmed)
Abstract：
BACKGROUND: Sclerotherapy has shown superior efficacy among the nonsurgical options for managing digital mucous cysts (DMC). Notably, previous research has indicated that bleomycin offers a more favorable side-effect profile and similar efficacy to conventional sclerosing agents.
OBJECTIVE: This study aimed to assess the efficacy and safety of bleomycin intralesional injection (ILI) for treating DMC through a comparative analysis of corticosteroid ILI and surgical excision.
METHODS: We retrospectively reviewed electronic medical records and clinical photographs. Telephone interviews were conducted to further investigate long-term treatment efficacy, safety, and overall treatment satisfaction.
RESULTS: Ten patients underwent surgical excision, and 13 and 15 patients received bleomycin and corticosteroid ILI, respectively. Both surgical excision and bleomycin ILI demonstrated superior treatment efficacy compared to corticosteroid ILI. No statistically significant difference in the treatment effectiveness between surgical excision and bleomycin ILI was observed. No significant adverse effects were observed. In the survey, the level of satisfaction was the highest for bleomycin ILI, followed by surgical excision and corticosteroid ILI.
CONCLUSIONS: This study revealed that bleomycin ILI exhibits a treatment efficacy higher than that of corticosteroid ILI and slightly lower than that of surgical excision, without any side effects. Therefore, bleomycin ILI is a safe and effective therapeutic option for the treatment of DMC.
OBJECTIVE: This study aimed to assess the efficacy and safety of bleomycin intralesional injection (ILI) for treating DMC through a comparative analysis of corticosteroid ILI and surgical excision.
METHODS: We retrospectively reviewed electronic medical records and clinical photographs. Telephone interviews were conducted to further investigate long-term treatment efficacy, safety, and overall treatment satisfaction.
RESULTS: Ten patients underwent surgical excision, and 13 and 15 patients received bleomycin and corticosteroid ILI, respectively. Both surgical excision and bleomycin ILI demonstrated superior treatment efficacy compared to corticosteroid ILI. No statistically significant difference in the treatment effectiveness between surgical excision and bleomycin ILI was observed. No significant adverse effects were observed. In the survey, the level of satisfaction was the highest for bleomycin ILI, followed by surgical excision and corticosteroid ILI.
CONCLUSIONS: This study revealed that bleomycin ILI exhibits a treatment efficacy higher than that of corticosteroid ILI and slightly lower than that of surgical excision, without any side effects. Therefore, bleomycin ILI is a safe and effective therapeutic option for the treatment of DMC.
摘要：
背景：硬化疗法在治疗指状黏液囊肿（DMC）的非手术选择中显示出优异的疗效。值得注意的是,先前的研究表明,博来霉素具有更有利的副作用,并且与常规硬化剂具有相似的疗效.
目的：本研究旨在通过皮质类固醇ILI和手术切除的比较分析，评估博来霉素病灶内注射（ILI）治疗DMC的疗效和安全性。
方法：我们回顾了电子病历和临床照片。进行电话访谈以进一步调查长期治疗效果,安全,总体治疗满意度。
结果：10例患者接受了手术切除，13和15例患者接受博来霉素和皮质类固醇ILI，分别。与皮质类固醇ILI相比，手术切除和博来霉素ILI均显示出更好的治疗效果。手术切除和博来霉素ILI之间的治疗效果没有统计学上的显着差异。没有观察到明显的不良反应。在调查中,博来霉素ILI的满意度最高，其次是手术切除和皮质类固醇ILI。
结论：这项研究表明，博来霉素ILI的治疗效果高于皮质类固醇ILI，略低于手术切除，没有任何副作用。因此,博来霉素ILI是治疗DMC的安全有效的治疗选择。
目的：本研究旨在通过皮质类固醇ILI和手术切除的比较分析，评估博来霉素病灶内注射（ILI）治疗DMC的疗效和安全性。
方法：我们回顾了电子病历和临床照片。进行电话访谈以进一步调查长期治疗效果,安全,总体治疗满意度。
结果：10例患者接受了手术切除，13和15例患者接受博来霉素和皮质类固醇ILI，分别。与皮质类固醇ILI相比，手术切除和博来霉素ILI均显示出更好的治疗效果。手术切除和博来霉素ILI之间的治疗效果没有统计学上的显着差异。没有观察到明显的不良反应。在调查中,博来霉素ILI的满意度最高，其次是手术切除和皮质类固醇ILI。
结论：这项研究表明，博来霉素ILI的治疗效果高于皮质类固醇ILI，略低于手术切除，没有任何副作用。因此,博来霉素ILI是治疗DMC的安全有效的治疗选择。
