未经证实:脊髓损伤(SCI)与几种胃肠道疾病有关,在这个人群中胆石症的患病率很高。因为SCI患者可能有不典型的症状和更晚期的疾病,一些治疗中心主张对SCI和胆结石患者进行预防性胆囊切除术.
UNASSIGNED:系统回顾SCI和胆石症患者预防性胆囊切除术研究的存在和质量。
UASSIGNED:根据PRISMA指南,使用Medline对截至2022年7月10日的文献进行了系统搜索,科克伦,和WebofScience数据库。使用的关键词是“胆囊切除术,“\”胆囊,胆石症,\"\"胆结石,“和”脊髓损伤。\"
未经评估:搜索确定了118篇文章,其中4人符合纳入标准。所有这些都是回顾性观察研究。4-16.5%的参与者进行了预防性胆囊切除术。胆囊切除术的病因为慢性胆囊炎合并胆绞痛(44.5-63.5%),急性胆囊炎(4-26%),胆总管结石(6-11%)和胰腺炎(2-6%)。手术时间,转化率,估计失血量,并发症的严重程度,SCI患者和有神经系统能力的患者的发病率和死亡率没有显著差异.
UNASSIGNED:尚未对SCI和胆结石患者进行预防性胆囊切除术和保守治疗的前瞻性队列研究。因此,没有有力的证据支持预防性胆囊切除术,需要进一步的研究.
UNASSIGNED: Spinal cord injury (SCI) is associated with several gastrointestinal disorders, and the prevalence of cholelithiasis is high in this population. Because individuals with SCI may have atypical symptoms and more advanced disease, some treatment centers advocate prophylactic cholecystectomy for patients with SCI and
gallstone disease.
UNASSIGNED: To systematically
review the existence and quality of studies on prophylactic cholecystectomy in individuals with SCI and cholelithiasis.
UNASSIGNED: A systematic search of literature up to July 10, 2022 was conducted in accordance with PRISMA guidelines using the Medline, Cochrane, and Web of Science databases. Keywords used were \"cholecystectomy,\" \"gallbladder,\" \"cholelithiasis,\" \"
gallstone,\" and \"spinal cord injury.\"
UNASSIGNED: The search identified 118 articles, of which 4 met the inclusion criteria. All these were retrospective observational studies. Prophylactic cholecystectomy was performed in 4-16.5% of the participants. The causes of cholecystectomy were chronic cholecystitis with biliary colic (44.5-63.5%), acute cholecystitis (4-26%), choledocholithiasis (6-11%) and pancreatitis (2-6%). Operative times, conversion rates, estimated blood loss, severity of complications, morbidity and mortality did not differ significantly between individuals with SCI and neurologically able individuals.
UNASSIGNED: No prospective cohort studies comparing prophylactic cholecystectomy with conservative management in individuals with SCI and
gallstone disease have been conducted. Therefore, there is no robust evidence to support prophylactic cholecystectomy and further studies are required.