关键词: Burden Cholelithiasis Conception Gallstone Gestation Gravidity Outbreak Pregnancy Prevalence

来  源:   DOI:10.1016/j.eurox.2023.100237   PDF(Pubmed)

Abstract:
UNASSIGNED: Gallstone disease is the second most common non-gynecological disease that may require surgical intervention during pregnancy. This study investigates the global prevalence of gallstones in pregnancy through a systematic review and meta-analysis.
UNASSIGNED: A systematic review and meta-analysis of studies that reported the global prevalence of gallstones in pregnancy was conducted. PubMed, Scopus, Web of Science, Embase, ScienceDirect, and Google Scholar were searched for studies published up to September 2022.
UNASSIGNED: In a review of 31 studies with a sample size of 190,714 people, the I2 heterogeneity test showed high heterogeneity (I2 = 98.8%). Therefore, the random effects method was used to analyze the results. The prevalence of gallstones was reported as 3.6% (95% CI: 1.9-6.7%). The highest prevalence of gallstones by continent was reported in America, at 6.8% (95% CI: 4.2-10.8%). The Egger test showed no evidence of publication bias (p = 0.609).
UNASSIGNED: Based on the results of this study, health policymakers should emphasize to the target community and the medical staff dealing with pregnant women the importance of screening for gallstones during pregnancy.
摘要:
胆结石病是第二常见的非妇科疾病,在怀孕期间可能需要手术干预。本研究通过系统评价和荟萃分析调查了妊娠期胆结石的全球患病率。
对报告妊娠期胆结石全球患病率的研究进行了系统评价和荟萃分析。PubMed,Scopus,WebofScience,Embase,ScienceDirect,和谷歌学者被搜索到2022年9月之前发表的研究。
在对31项研究的回顾中,样本量为190,714人,I2异质性检验显示高度异质性(I2=98.8%)。因此,采用随机效应法对结果进行分析。据报道,胆结石的患病率为3.6%(95%CI:1.9-6.7%)。据报道,美洲的胆结石患病率最高,6.8%(95%CI:4.2-10.8%)。Egger测试表明没有发表偏倚的证据(p=0.609)。
根据这项研究的结果,卫生政策制定者应向目标社区和处理孕妇的医务人员强调怀孕期间筛查胆结石的重要性。
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