PDF(Pubmed)
Abstract：
UNASSIGNED: A sialolith is a salivary stone usually presenting with swelling and pain in the affected salivary gland, most commonly the submandibular gland. There have been speculations about the association between this condition and other systemic diseases, especially those forming stones, such as nephrolithiasis and cholelithiasis. This systematic review and meta-analysis aimed to summarize the studies assessing the relationship between cholelithiasis and sialolithiasis.
UNASSIGNED: PubMed/MEDLINE, Scopus, Web of Science, and Embase electronic databases were searched according to the keywords related to both disorders without any publication date or language restriction. Case-control and cohort studies evaluating the relationship between salivary and biliary stones were considered eligible. Quality assessment was performed following Newcastle-Ottawa Scale (NOS) for quality assessment of case-control studies. All meta and statistical analyses were performed with Comprehensive Meta-Analysis software.
UNASSIGNED: Two studies fully complied with the defined eligibility criteria and were included, both of which were case-control studies using national-scale databases. In both surveys, the prevalence of previous gallstones in patients with sialolithiasis was compared to that of a control group. Though one of the studies found that there is no relationship between sialolithiasis and cholelithiasis, the meta-analysis revealed that previous cholelithiasis is significantly more prevalent among patients with sialolithiasis (P = 0.000), with an odds ratio of 2.04.
UNASSIGNED: It seems that cholelithiasis is significantly associated with an increase in salivary stone formation. Therefore, a thorough salivary examination in all patients declaring current or past cholelithiasis is recommended. However, more studies, especially prospective cohorts, are needed to make firmer conclusions.
UNASSIGNED: PubMed/MEDLINE, Scopus, Web of Science, and Embase electronic databases were searched according to the keywords related to both disorders without any publication date or language restriction. Case-control and cohort studies evaluating the relationship between salivary and biliary stones were considered eligible. Quality assessment was performed following Newcastle-Ottawa Scale (NOS) for quality assessment of case-control studies. All meta and statistical analyses were performed with Comprehensive Meta-Analysis software.
UNASSIGNED: Two studies fully complied with the defined eligibility criteria and were included, both of which were case-control studies using national-scale databases. In both surveys, the prevalence of previous gallstones in patients with sialolithiasis was compared to that of a control group. Though one of the studies found that there is no relationship between sialolithiasis and cholelithiasis, the meta-analysis revealed that previous cholelithiasis is significantly more prevalent among patients with sialolithiasis (P = 0.000), with an odds ratio of 2.04.
UNASSIGNED: It seems that cholelithiasis is significantly associated with an increase in salivary stone formation. Therefore, a thorough salivary examination in all patients declaring current or past cholelithiasis is recommended. However, more studies, especially prospective cohorts, are needed to make firmer conclusions.
摘要：
■唾液石是一种唾液结石，通常在受影响的唾液腺中表现为肿胀和疼痛，最常见的是颌下腺。有人猜测这种情况与其他系统性疾病之间的联系，尤其是那些形成石头的，如肾结石和胆石症。本系统综述和荟萃分析旨在总结评估胆石症与唾液酸结石之间关系的研究。
■PubMed/MEDLINE,Scopus,WebofScience,根据与这两种疾病相关的关键词搜索Embase电子数据库,没有任何发表日期或语言限制.评估唾液和胆道结石之间关系的病例对照和队列研究被认为是合格的。根据纽卡斯尔-渥太华量表（NOS）进行质量评估，以评估病例对照研究的质量。所有Meta分析和统计学分析均采用综合Meta分析软件进行。
■两项研究完全符合定义的资格标准，并纳入其中，这两项研究均为使用国家规模数据库的病例对照研究.在两项调查中，将唾液管结石患者既往胆结石的患病率与对照组进行比较.尽管其中一项研究发现，唾液酸结石和胆石症之间没有关系，荟萃分析显示，既往胆石症患者中胆石症明显更普遍（P=0.000），赔率比为2.04。
■胆石症似乎与唾液结石形成的增加显着相关。因此,建议对所有宣布当前或过去胆石症的患者进行彻底的唾液检查.然而,更多研究,尤其是预期的队列，需要做出更坚定的结论。
■PubMed/MEDLINE,Scopus,WebofScience,根据与这两种疾病相关的关键词搜索Embase电子数据库,没有任何发表日期或语言限制.评估唾液和胆道结石之间关系的病例对照和队列研究被认为是合格的。根据纽卡斯尔-渥太华量表（NOS）进行质量评估，以评估病例对照研究的质量。所有Meta分析和统计学分析均采用综合Meta分析软件进行。
■两项研究完全符合定义的资格标准，并纳入其中，这两项研究均为使用国家规模数据库的病例对照研究.在两项调查中，将唾液管结石患者既往胆结石的患病率与对照组进行比较.尽管其中一项研究发现，唾液酸结石和胆石症之间没有关系，荟萃分析显示，既往胆石症患者中胆石症明显更普遍（P=0.000），赔率比为2.04。
■胆石症似乎与唾液结石形成的增加显着相关。因此,建议对所有宣布当前或过去胆石症的患者进行彻底的唾液检查.然而,更多研究,尤其是预期的队列，需要做出更坚定的结论。
