背景:该研究调查了跌倒或跌倒风险较高的老年人客观和主观测量的肌肉质量与身体活动水平之间的相关性。
方法:FITNESS(针对新的肌节病社会的秋季兴趣)是一个多中心(法国昂热大学医院,里尔,利摩日和Orléans),横截面,法国多学科医院会诊中常规护理的观察性研究。纳入标准为≥75岁,住在家里和咨询跌倒或步态障碍。标准化的老年评估,通过阻抗法评估肌肉质量,在纳入患者时,通过连续活动测定(5天)和附带和计划运动问卷(IPEQ)进行身体活动。
结果:170名75岁及以上的人被纳入FITNESS研究(平均年龄82.9±4.7岁,女性72.9%)。肌肉质量(全身和下肢)与活性能量消耗(AEE,ρ全身=0.32,p值<0.001;ρ下肢=0.25,p值=0.003),但不是每天的步数,也没有IPEQ分数。全身肌肉质量的多变量分析显示与AEE和白蛋白水平以及下肢肌肉质量呈正相关,与AEE和Charlson呈正相关。
结论:这项研究表明,在跌倒和/或跌倒风险较高的老年人群中,肌肉质量的损失与体力活动的减少有关。因此,跌倒或跌倒风险高的受试者构成了一个特殊的群体,对他们来说,与久坐的生活方式和维持身体活动的斗争应该是双重优先事项。
BACKGROUND: The
study investigates the correlation between muscle mass and physical activity level measured objectively and subjectively in older adults who fall or are at high risk of falling.
METHODS: FITNESS (Fall Interest to Target Newly Sarcopenic Society) is a multi-center (French university hospitals of Angers, Lille, Limoges and Orléans), cross-sectional, observational
study of routine care within a French multidisciplinary hospital consultation. Inclusion criteria were ≥ 75 years old, living at home and consulting for fall or gait disorder. A standardized geriatric assessment, muscle mass evaluation by impedancemetry, physical activity by continuous actimetry (5 days) and Incidental and Planned Exercise Questionnaire (IPEQ) were performed at patient inclusion.
RESULTS: 170 people aged 75 and over were included in the FITNESS
study (mean age 82.9 ±4.7 years, women 72.9%). Muscle mass (whole body and lower limbs) correlated with active energy expenditure (AEE, ρ whole body = 0.32, p-value < 0.001; ρ lower limbs = 0.25, p-value = 0.003), but not with number of daily steps, nor with IPEQ score. Multivariate analysis of whole-body muscle mass showed a positive and significant association with AEE and albumin levels and for lower limb muscle mass, a positive association with AEE and Charlson.
CONCLUSIONS: This
study suggests that in the particular population of older adults who fall and/or are at high risk of falling, loss of muscle mass correlates with reduced physical activity. So subjects who fall or at high risk of falling constitute a special group for whom the fight against sedentary lifestyles and the maintenance of physical activity should be a dual priority.