Endocrine-disrupting compounds

内分泌干扰化合物
  • 文章类型: Journal Article
    制药,个人护理产品(PPCP),和内分泌干扰化合物(EDC)的使用最近持续增加,导致废水中的排放和积累增加。传统的水处理和消毒方法在有效解决这种微污染物问题方面有些受限。超声(美国),作为高级氧化过程,是基于超声波照射的原理,将水暴露在高频波中,诱导H2O热分解,同时使用产生的自由基氧化和分解溶解的污染物。这篇综述评估了过去五年对基于美国的有效降解水中EDC和PPCP的技术的研究,并评估了可能影响去除率的各种因素:溶液pH值,水的温度,背景常见离子的存在,天然有机物,作为启动子和清除剂的物种,和美国条件的变化(例如,频率,功率密度,和反应类型)。这篇综述还讨论了各种类型的碳/非碳催化剂,O3和紫外工艺结合US工艺可进一步提高EDC和PPCP的降解效率。此外,考虑了许多类型的EDC和PPCPs以及这些有机污染物的最新研究趋势。
    Pharmaceuticals, personal care products (PPCPs), and endocrine-disrupting compounds (EDCs) have seen a recent sustained increase in usage, leading to increasing discharge and accumulation in wastewater. Conventional water treatment and disinfection processes are somewhat limited in effectively addressing this micropollutant issue. Ultrasonication (US), which serves as an advanced oxidation process, is based on the principle of ultrasound irradiation, exposing water to high-frequency waves, inducing thermal decomposition of H2O while using the produced radicals to oxidize and break down dissolved contaminants. This review evaluates research over the past five years on US-based technologies for the effective degradation of EDCs and PPCPs in water and assesses various factors that can influence the removal rate: solution pH, temperature of water, presence of background common ions, natural organic matter, species that serve as promoters and scavengers, and variations in US conditions (e.g., frequency, power density, and reaction type). This review also discusses various types of carbon/non-carbon catalysts, O3 and ultraviolet processes that can further enhance the degradation efficiency of EDCs and PPCPs in combination with US processes. Furthermore, numerous types of EDCs and PPCPs and recent research trends for these organic contaminants are considered.
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  • 文章类型: Journal Article
    不孕症是一个日益严重的健康问题,影响全球约15%的夫妇。常规精液参数对男性不育潜力测定的准确性有限。对男性不育的认识的当前进展表明,环境和职业暴露于化学污染物是导致不育问题的重要病因。在这种情况下,一些重金属(HM)可以被认为是内分泌干扰化合物(EDC),从而改变了精液的质量。本系统综述旨在总结检测和量化人类精浆(SP)中HMs的关键点以及所涉及的分析工具。我们的结果表明,对于HM定量,原子吸收光谱(AAS)和电感耦合等离子体(ICP)是最常用的技术,而Zn,Cd,Pb,和Cr是最经常检测到的分析物。快,可靠,SP中EDC的灵敏定量对于制定准确的诊断和预防策略以解决男性不育症,从而提供个性化治疗可能很重要。
    Infertility is a growing concerning health problem affecting around 15% of couples worldwide. Conventional semen parameters have limited accuracy for male infertility potential determination. Current advances in the understanding of male infertility indicate that environmental and occupational exposure to chemical contaminants are important etiological factors leading to infertility problems. In this context, some heavy metals (HMs) can be considered as endocrine-disrupting compounds (EDCs), thus altering the seminal quality. This systematic review aims to summarize the key points to detect and quantify HMs in human seminal plasma (SP) and the involved analytical tools. Our results showed that that for HM quantification, atomic absorption spectroscopy (AAS) and inductively coupled plasma (ICP) were the most employed techniques while Zn, Cd, Pb, and Cr were the analytes most often detected. Fast, reliable, and sensitive quantification of EDCs in SP could be important for the development of accurate diagnostic and preventive strategies to address male infertility towards providing personalized therapy.
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  • 文章类型: Journal Article
    Contaminants of emerging concerns such as endocrine-disrupting compounds (EDCs) and pharmaceuticals/personal-care products (PPCPs) constitute a problem since they are not completely eliminated by traditional water and wastewater treatment methods. Non-thermal plasma (NTP) is considered as one of the most favorable treatment methods for the removal of organic contaminants in water and wastewater. The degradation of selected EDCs and PPCPs of various classes was reviewed, based on the recent literature, to (i) address the effect of the main NTP treatment parameters (water quality and NTP conditions: pH, initial concentration, temperature, background common ion, NOM, scavenger, gas type/flow rate, discharge/reactor type, input power, and energy efficiency/yield) on the degradation of contaminants and their intermediates, (ii) assess the influences of different catalysts and hybrid systems on degradation, (iii) describe EDC and PPCP degradation along with their properties, and (iv) evaluate mineralization, pathway, and degradation mechanism of selected EDCs and PPCPs for different cases studied. Furthermore, areas of potential research in NTP treatment for the degradation of EDCs and PPCPs in aqueous solutions are recommended. It could be reasonably predicted that this review is valid for developing our understanding of the fundamental scientific principles concerning the catalytic NTP of EDCs and PPCPs, providing helpful and practical references for researchers and designers on the effective removal of EDCs/PPCPs and the optimized operation of catalytic NTP systems.
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  • 文章类型: Journal Article
    Every year millions of tons of plastic are produced around the world and humans are increasingly exposed to them. This constant exposure to plastics has raised some concerns against human health, particularly when it comes to phthalates. These compounds have endocrine-disrupting properties, as they have the ability to bind molecular targets in the body and interfere with hormonal function and quantity. The main use of phthalates is to give flexibility to polyvinyl chloride (PVC) polymers. Phthalates are found in a variety of industrial and consumer products, and as they are not covalently bound to the plastic, phthalates contaminate the environment from which human exposure occurs. Studies in human and animal populations suggest a correlation between phthalate exposure and adverse health outcomes, particularly at the reproductive and cardiovascular systems, however there is much less information about the phthalate toxicity of the later. Thus, the main purpose of this review is to present the studies relating the effects already stated of phthalates on the cardiovascular and reproductive systems, and also present the link between these two systems.
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  • 文章类型: Journal Article
    This review provides a brief survey of the biological effects of selected endocrine-disrupting compounds that are formed after internal exposure of organisms. Further, the present analytical methods available for the determination of these compounds in foodstuffs are critically evaluated. The attention is primarily devoted to the methods for sample pretreatment, which are the main source of errors and are usually the most time-consuming step of the whole analysis. This review is focused on selected natural and synthetic estrogens, estrogen conjugates, and chemical additives used in the plastic industry that can act as estrogen mimics.
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