■单心室生理的患者在接受姑息性手术后,循环功率继续不足。本文提出了一种配有柔性叶片的右心辅助装置,为这些患者提供循环辅助。通过数值模拟研究了柔性叶片的最佳弹性模量。
■采用单向流体-结构相互作用(FSI)模拟来研究柔性叶片在旋转过程中的变形及其对设备性能的影响。该过程开始于计算流体动力学(CFD)模拟,以计算血压升高和叶片表面的压力。随后,这些压力数据被导出用于有限元分析(FEA)以计算叶片的变形。然后根据变形的叶片形状重建流体域。进行迭代CFD和FEA模拟,直至血压升高且叶片形状稳定。血压升高,溶血风险,对不同弹性模量叶片的血栓形成风险进行详尽评估,以确定最佳弹性模量。
■除了在8,000rpm下叶片弹性模量为40MPa的情况外,在研究范围内与柔性叶片相关的压力上升(转速为4,000rpm和8,000rpm,10MPa至200MPa之间的弹性模量)低于刚性叶片。观察到,随着弹性模量的增加,对应于柔性叶片的压力升高也随之增加。此外,不同弹性模量的柔性叶片与刚性叶片在溶血风险和血栓风险方面无显著差异。
■除了一个特定的案例,柔性叶片在研究范围内的变形导致叶轮的功能下降。值得注意的是,与叶片变形相比,转速对溶血风险和血栓风险的影响更大.经过对叶片压缩性的综合分析,血压升高,溶血风险,和血栓风险,确定柔性叶片的最佳弹性模量在40MPa和50MPa之间。
UNASSIGNED: Patients with single-ventricle physiologies continue to experience insufficient circulatory power after undergoing palliative surgeries. This paper proposed a right heart assist device equipped with flexible blades to provide circulatory assistance for these patients. The optimal elastic modulus of the flexible blades was investigated through numerical simulation.
UNASSIGNED: A one-way fluid-structure interaction (FSI) simulation was employed to
study the deformation of flexible blades during rotation and its impact on device performance. The process began with a computational fluid dynamics (CFD) simulation to calculate the blood pressure rise and the pressure on the blades\' surface. Subsequently, these pressure data were exported for finite element analysis (FEA) to compute the deformation of the blades. The fluid domain was then recreated based on the deformed blades\' shape. Iterative CFD and FEA simulations were performed until both the blood pressure rise and the blades\' shape stabilized. The blood pressure rise, hemolysis risk, and thrombosis risk corresponding to blades with different elastic moduli were exhaustively evaluated to determine the optimal elastic modulus.
UNASSIGNED: Except for the case at 8,000 rpm with a blade elastic modulus of 40 MPa, the pressure rise associated with flexible blades within the studied range (rotational speeds of 4,000 rpm and 8,000 rpm, elastic modulus between 10 MPa and 200 MPa) was lower than that of rigid blades. It was observed that the pressure rise corresponding to flexible blades increased as the elastic modulus increased. Additionally, no significant difference was found in the hemolysis risk and thrombus risk between flexible blades of various elastic moduli and rigid blades.
UNASSIGNED: Except for one specific case, deformation of the flexible blades within the studied range led to a decrease in the impeller\'s functionality. Notably, rotational speed had a more significant impact on hemolysis risk and thrombus risk compared to blade deformation. After a comprehensive analysis of blade compressibility, blood pressure rise, hemolysis risk, and thrombus risk, the optimal elastic modulus for the flexible blades was determined to be between 40 MPa and 50 MPa.