背景:近年来,夹缝嫁接的兴趣重新兴起,源于它的简单性,安全,和恢复组织完整性的潜力。虽然历史上用于慢性不愈合的伤口,捏移植物在外科手术后显示出希望,特别是那些涉及下肢的。
目的:对文献进行系统回顾,并对捏合嫁接的当前应用进行最新概述。
方法:根据系统评价和荟萃分析指南的首选报告项目进行系统评价。与医学参考图书馆员合作,PubMed,Embase,Scopus,和WebofScience数据库进行了搜索,以获得从2000年开始使用捏合嫁接的研究报告。还筛选了每个纳入文章的参考文献。
结果:十篇文章符合最终纳入标准。总的来说,300例患者接受了挤压移植治疗皮肤溃疡,另外35例作为皮肤癌切除术后原发性闭合的替代方案。总的来说,捏移植是安全的和良好的耐受性,报告的不良结局最小。
结论:夹缝嫁接是安全的,直截了当,以及促进慢性伤口愈合的有效技术。虽然该程序在皮肤病外科的新兴应用中显示出早期的希望,只有大约10%的报告病例涉及这种适应症,反映了在这一领域进一步研究的需要。
BACKGROUND: Pinch grafting has experienced a resurgence in interest in recent years, stemming from its simplicity, safety, and potential in restoring tissue integrity. While historically employed for chronic nonhealing wounds, pinch grafts have shown promise following surgical procedures, particularly those involving the lower extremities.
OBJECTIVE: To systematically
review the literature and present an updated overview of the current applications of pinch grafting.
METHODS: A systematic
review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. In collaboration with a medical reference librarian, the PubMed, Embase, Scopus, and Web of Science databases were searched for studies reporting on the use of pinch grafting from 2000 onward. The references of each included article were also screened.
RESULTS: Ten articles met final inclusion criteria. In total, 300 patients underwent pinch grafting for treatment of skin ulceration, while an additional 35 cases were performed as an alternative to primary closure following skin cancer resection. Overall, pinch grafting was safe and well tolerated, with minimal adverse outcomes reported.
CONCLUSIONS: Pinch grafting is a safe, straightforward, and effective technique to promote the healing of chronic wounds. While the procedure shows early promise in emerging applications within dermatologic surgery, only about 10% of the reported cases involved this indication, reflecting a need for further research in this area.