{Reference Type}: Systematic Review
{Title}: Incidence of Bacteremia, Infective Endocarditis, or Prosthetic Joint Infection in Dermatologic Surgery: A Systematic Review.
{Author}: McKesey J;Mazhar M;Alam M;Srivastava D;Nijhawan RI;
{Journal}: Dermatol Surg
{Volume}: 50
{Issue}: 5
{Year}: 2024 May 1
{Factor}: 2.914
{DOI}: 10.1097/DSS.0000000000004101
{Abstract}: <B>BACKGROUND: </B>Prophylactic antibiotic therapy is widely used in dermatologic surgery to prevent surgical site infections and bacteremia, which can lead to prosthetic joint infections (PJI) and infective endocarditis (IE) in high-risk populations.<BR><B>OBJECTIVE: </B>To evaluate the incidence of bacteremia, PJI, and IE after dermatologic surgery and assess the current evidence for antibiotic prophylaxis.<BR><B>METHODS: </B>A search of the computerized bibliographic databases was performed using key terms from the date of inception to March 21, 2021. Data extraction was performed independently by 2 data extractors.<BR><B>RESULTS: </B>The review resulted in 9 publications that met inclusion criteria, including 5 prospective cohort studies and 4 case reports or case series. The prospective studies reported a wide range of bacteremia incidence (0%-7%) after dermatologic surgery. No cases of PJI resulting directly from cutaneous surgery were identified, and only 1 case series reported IE after various skin procedures.<BR><B>CONCLUSIONS: </B>These findings suggest a low rate of bacteremia and a lack of direct evidence linking dermatologic surgery to PJI or IE. The scarcity of published data on this topic is a limitation, highlighting the need for further research, particularly randomized controlled trials, to guide antibiotic prophylaxis recommendations.