The process of linking an offender to a crime scene via their fingerprints has historically required significant human effort to compare latent fingerprints recovered from the scene with known fingerprints of a suspect. Increasing the speed of such comparisons, whilst maintaining accuracy and reliability and minimising error, is crucial for providing rapid intelligence to police investigators. One major opportunity for streamlining fingerprint examination is the adaptation of \'lights-out\' technology to the comparison and matching of latent fingerprints. Here, we review the development, trial and validation process undertaken by the Queensland Police Service (QPS), Australia, to support implementation of a lights-out latent (LOL) workflow for automated latent fingerprint searching that is fully integrated with the existing case management systems. Targeted trials were undertaken using random selections of previously identified latent fingerprints that were searched using the LOL workflow against a local 10-print database. The results suggested that the LOL workflow could identify up to 44% of latent fingerprints with minimal human intervention and supported its implementation for all latent fingerprint comparisons in QPS casework. Review of LOL casework comparison outcomes for 2019 revealed that LOL-based identifications contributed approximately one quarter of all fingerprint identifications. Several procedural and technical factors that influenced the speed and efficiency of the LOL workflow are discussed, along with opportunities for improvement and future validation as an expert system.

Identification has always been very vital in forensic casework. Fingerprint patterns are population-specific and individualistic, that makes fingerprinting an important biological trait in human biology and forensics. Fingerprint is an impression of the friction ridges of the finger-ball, where friction ridges are raised portions of the epidermis. Skin on human fingertips contains ridges and valleys which together forms distinctive patterns. These patterns are fully developed in intra-uterine life and remain unaltered until the death of the individual. Injuries such as cuts, burns and bruises can temporarily damage quality of fingerprints but when fully healed, the patterns are restored. The number of ridges present in a unit area on a fingerprint is called the Fingerprint Ridge Density (FPRD). The epidermal ridge density can be determined by examining two parameters - ridge width and distance between the ridges. The thickness of the epidermal ridges varies between individuals and between the sexes. The present review of literature focuses on the sexual dimorphism on the basis of the FPRD and its possible use in forensic examinations. Most of the studies pertaining to the estimation of sex from the FPRD have been conducted in the last two decades when Mark A. Acree in 1999, devised a method of estimation of sex on Caucasian and African-American descent. The present analysis evaluates the studies found in the PubMed database conducted after Acree, 1999. The estimation of sex from the FPRD is based upon the fact that the females have a fine detailing of ridges and consequently more ridges are covered in a unit space in the fingerprints of females as compared to males. The paper also highlights -recent advancements and future perspectives in the area of FPRD. (www.actabiomedica.it).

Mummified tissue presents challenges for fingerprinting due to rigidity, shrinkage, and other features obscuring epidermal ridge detail. A new cost-effective in-house solution was developed to obtain good quality fingerprints from mummified remains. The simplified procedure uses a sodium carbonate:sodium acetate mixture easily prepared using commonly available chemical products. An overview of the methods and solutions utilized to date for rehydration and restoration illustrates the main benefits of the developed formulation: the solution provided better tissue pliability and turgor than the sodium carbonate:ethanol formulation of Rüffer previously employed; the prepared solution proved stable for weeks at room temperature and poses minimum hazard risk to users. It functions as a weak base (pH 9.3) and is sufficiently corrosive to allow tissue softening over a flexible timeframe of 1-5 days without causing any damage. The degree of effectiveness for rehydration of mummified tissue and restoration of ridge detail is attributed to three synergistic aspects: increased turgor as provided by a penetrating humectant and water; softening and pliability as a result of pH and any specific chemical interaction that affects calcium in collagen; ridge detail definition as a function of turgor and softening, with some secondary corrosive dependency related to the pH of a solution.

Whilst many identification methods have been widely described and discussed in the literature, and considered in disaster and humanitarian contexts, there has been limited reporting and evaluation of the identification methods used in domestic medico-legal death investigation contexts. The aim of this study was to evaluate the identification methods utilised at the Victorian Institute of Forensic Medicine (VIFM), which forms part of a coronial medico-legal death investigation system. The method of identification and time taken to complete the identification were reviewed for all cases admitted to the VIFM over a five-year period from 1 July 2015 to 30 June 2020. The majority, 91%, of individuals admitted to the VIFM were visually identified. The remaining 9% of cases required identification by primary methods (i.e. fingerprints, DNA or dental) or, when those methods were not possible, by secondary methods (i.e. circumstantial). Visual identifications were the timeliest, taking an average of 1.5 days, whilst primary identification methods required an average of 5 days to complete. The triaging of identification methods, dependent on the case context, body preservation, availability of ante-mortem data, legal requirements and admissibility of the method, are determined by identification coordinators within the Human Identification Service (HIS) to ensure the most appropriate and timely method is employed. This review of human identification methods provides the foundation for future analyses to compare workflow processes and improve identification methods utilised in domestic medico-legal contexts.

BACKGROUND: DOORS syndrome (deafness, onychodystrophy, osteodystrophy, mental retardation and seizures; MIM 220500) is a rare multisystem genetic disorder, mainly characterized by sensorineural deafness, shortened terminal phalanges with small nails of hands and feet, intellectual deficit, and seizures. The disease is caused by homozygous or compound heterozygous mutation in the TBC1 domain family member 24 (TBC1D24) gene (gene locus/MIM 613577) on chromosome 16p13.
OBJECTIVE: We report the first case of DOORS syndrome from Indonesia.
METHODS: A review of the literature was conducted and cases compared.
RESULTS: A 27-day-old baby girl was brought to us with a history of recurrent seizures and absence of all finger- and toenails since birth. In addition, physical examination revealed left eye strabismus and a single transverse palmar crease on both hands. X-rays of the hands and feet showed absence of the distal phalanx of her right and left fingers II-V and the distal phalanx of her right and left toes I-V, respectively. Brainstem-evoked response audiometry test revealed profound bilateral sensorineural deafness. Pentalogy of Fallot was diagnosed by echocardiography, while an abnormal diffuse epileptiform pattern was found on electroencephalography.
CONCLUSIONS: This is the first report of an association between pentalogy of Fallot and single transverse palmar crease in DOORS syndrome.

Hand-foot syndrome (HFS) is the main side effect of capecitabine and affects the compression zones of the body such as the palms and soles, causing numbness, paresthesias, skin swelling or erythema, scaling, chapping, hard nodule-like blisters, and severe pain. Loss of fingerprints is also observed in some cases. Severe cases of HFS are common in the review of clinical reports. However, loss of fingerprints has not received significant attention. Two reported cases of loss of fingerprints in The New England Journal of Medicine and The BMJ have drawn attention to this side effect of capecitabine. Loss of fingerprints has a serious impact on patients\' daily life, especially on personal identification. This report describes a patient who lost her fingerprints during the early stage of chemotherapy. Our aim is to draw the medical profession\'s attention to this problem.

Optical coherence tomography (OCT) is an interferometric imaging technique that has revolutionized clinical ophthalmology since the first half of the 1990\'s. Despite this approach being successfully employed in ophthalmology and having great potential in forensic cases, its use in different forensic fields appears to be quite limited. In this review we reviewed the scientific literature regarding the application of OCT in forensic science and legal medicine from 1995 to 2019. Our research showed the usefulness of this approach for the study of coronary injuries, postmortem ocular changes, forensic entomology, and several other applications of specific forensic interest (the study of blood stains, fingerprints, and hair bulbs for personal identification, as well as the study of materials found in the crime scene for comparation, or anti-fraud investigation). The creation of specific \'ad hoc\' devices and a better knowledge of this type of technology by pathologists will be a fundamental step to continue to develop the use of OCT forensic fields.

This study addresses the permanence and persistence of friction ridges and the persistence of impressions made from these friction ridges over months and years. Permanence is the unchanging presence and appearance of friction ridge arrangements and their attributes between recurring observations of the skin. Permanence was evaluated from direct photographs of fingers collected over a period of 30-45 days (covering one or more skin regeneration cycles) as well as after 8 or more years had elapsed. Persistence embodies the operational concept of whether or not a pair of images displays sufficient similarity upon which to base an informed decision that they were made by the same finger, while acknowledging certain dissimilarities or distortions due to friction ridge physiology, image capture, matrix, substrate, and applied pressure. Persistence applies to both friction ridge skin and impressions made from these friction ridges. Permanence and persistence of skin were assessed from direct photographs of fingers taken two months apart and from finger photographs separated by an interval of at least 8 years. Permanence and persistence were also assessed from impressions taken over 4 months, as well as those separated by 8-53 years. Variability due to capture method was assessed by using four image capture methods over a four month period: direct photography of fingers, impressions captured by ink, holographic imaging, and live scan. Qualified latent fingerprint examiners assessed all changes observed over time, as well as any limitations imposed by capture method. The practice of comparison and identification of fingerprint impressions was upheld, as was the prevailing use of the word persistence to describe stability of friction ridges. All photographs and impressions of the same finger were identifiable as originating from the same source. Within all the periods of observation, level 1 detail was permanent and persistent. Persistence, but not permanence, was supported for level 2 detail. Notably, the small changes observed were only in appearance; there were no changes in the presence of new, or absence of existing, minutiae. Level 3 details of ridge edge shape and pore presence were neither permanent nor persistent. Ridge width was permanent and persistent. Incipient ridges were neither permanent nor persistent.

With a reliance on the various forms of forensic science evidence in complex criminal investigations, the measures for ensuring its quality are facing increasing scrutiny. Improvements to quality management systems, to ensure both the robust application of scientific principles and the accurate interpretation and reporting of results, have arisen as a consequence of high-profile rebuttals of forensic science evidence, combined with process improvements driven by evaluation of current practice. These improvements are crucial to ensure validity of results as well as providing assurance for all those involved in the Criminal Justice System. This work first examines the quality management systems utilised for the examination and analysis of fingerprint, body fluid and DNA evidence. It then proceeds to highlight an apparent lack of comparable quality assurance mechanisms within the field of digital forensics, one of the newest branches of forensic science. Proposals are provided for the improvement of quality assurance for the digital forensics arena, drawing on the experiences of, and more well-established practices within, other forensic disciplines.

An extensive literature review and new post-irradiation experimental results are presented of genotyping blood stains and hair, and physical examinations of latent fingerprints, hairs, and fibers. Results indicate that successful development of nuclear short tandem repeat (STR) and mitochondrial DNA sequence profiles from human blood and hair evidence is possible-up to a point-following exposure to gamma, neutron, beta, and alpha radiation at several levels that would most likely be present at this type of crime scene (i.e., a \"dirty bomb,\" etc.). Commencing at gamma radiation levels between 90 and 900kGy, DNA analysis using conventional DNA techniques was unsuccessful. In general, irradiation negatively affected the quality of latent fingerprints. All four radiation types degraded most fingerprint samples at all doses; nevertheless, many fingerprints remained of value for potential use in comparison. Although variable from one hair to another, microscopic changes observed for all types and levels of irradiation could potentially result in false exclusions. Negligible microscopic changes were observed in papers and fibers (used as substrates for fingerprints and bloodstains) up to 90kGy gamma, but fluorescence of fibers began to change above that dose. Paper and fibers, as well as plastic evidence enclosures, became extremely brittle leading to breakage after a gamma dose of 900kGy.