背景:DDH的既定相关因素包括女性,臀位介绍,家族史,先天性畸形,羊水过少,和母体甲状腺功能亢进.然而,可能导致DDH的环境因素的证据有限且不一致。
方法:对医学文献进行了系统回顾,以收集有关环境因素的数据,包括纬度,经度,年平均降水量,年平均气温,月最低温度,和每月最高温度,来自所有发表关于DDH文章的机构。单因素线性回归分析环境因素与DDH发病率的相关性,同时进行多元回归分析以确定DDH发生率的显著相关因素。
结果:分析了总共93份独特手稿的数据,显示DDH发病率与温度之间存在显著负相关,包括年平均气温(r=-0.27,p=0.008),月最低温度(r=-0.28,p=0.006),月最高气温(r=-0.23,p=0.029)。此外,DDH发病率与纬度呈显著正相关(r=0.27,p=0.009),DDH发病率与年平均降水量呈显著负相关(r=-0.29,p=0.004)。在最终的多元回归分析中,温度,包括年平均气温,月最低温度,和每月最高温度,被确定为DDH发病率的显著相关因素。
结论:这项研究的结果表明寒冷天气与DDH发病率之间存在关联。进一步的研究应该探索寒冷天气和DDH发病率之间的联系,提供对寒冷气候的潜在干预措施的见解。
BACKGROUND: Established associated factors for
DDH include female sex, breech presentation, family history, congenital malformations, oligohydramnios, and maternal hyperthyroidism. However, evidence for environmental factors that may contribute to
DDH is limited and inconsistent.
METHODS: A systematic
review of medical literature was conducted to collect data on environmental factors, including latitude, longitude, average yearly precipitation, average yearly temperature, minimum monthly temperature, and maximum monthly temperature, from all institutions that published articles on
DDH. Univariate linear regression analysis was used to examine the correlation between environmental factors and DDH incidence, while multiple regression analysis was conducted to identify significant associated factors for DDH incidence.
RESULTS: Data from a total of 93 unique manuscripts were analyzed, revealing a significant negative correlation between
DDH incidence and temperature, including average yearly temperature (r = -0.27, p = 0.008), minimum monthly temperature (r = -0.28, p = 0.006), and maximum monthly temperature (r = -0.23, p = 0.029). Additionally, there was a significant positive correlation between DDH incidence and latitude (r = 0.27, p = 0.009), and a significant negative correlation between DDH incidence and average yearly precipitation (r = -0.29, p = 0.004). In the final multiple regression analysis, temperature, including average yearly temperature, minimum monthly temperature, and maximum monthly temperature, were identified as significant associated factors for DDH incidence.
CONCLUSIONS: The findings of this study suggest an association between cold weather and DDH incidence. Further research should explore the link between cold weather and DDH incidence, offering insights into potential interventions for cold climates.