背景:大多数严重失血性休克的重症通气患者会出现代谢性酸中毒,低蛋白血症,电解质不平衡,增加自由基的产生。Channastriata的白蛋白含量很高,一种有助于体内平衡的必需结合蛋白,当与辣木和姜黄合用时,它们作为强大的抗氧化剂。C.striata的管理,M.oleifera,和黄草提取物口服可能有益于患者的血液动力学问题,包括大量失血。
方法:一名40岁的印尼妇女因第三个孩子分娩后10天胎盘滞留时间延长导致3级失血性休克导致意识下降,来到急诊科。她进行了紧急子宫切除术,并被送往重症监护病房,血红蛋白水平为4.2gr/dL,尽管在手术期间已经收到了两袋包装的红细胞,在重症监护室的第一天,她继续带着四个包。病人进行了通风,有血管加压药支持,白蛋白水平低,为2.1gr/dL。她的血液动力学特征很难稳定,持续的胃残留物和定期排尿量小于1cc/kg/小时,从而减缓呼吸机和血管加压药的断奶过程。口服补充纹状体梭菌,M.oleifera,并且在第二天给予黄草梭菌,每6小时分成三个剂量。第二次给药后,第三次给药后,胃残留物开始消退并消失。患者的病情在接下来的24小时内有所改善;她在第四天被拔管并出院。
结论:这是描述纹状体梭菌作用的首例病例报告,M.oleifera,和黄草提取物用于因胎盘延长而患有严重失血性休克的患者。加速恢复显示了C.striata的可能好处,M.oleifera,和黄草提取物在稳定致癌压力中,中和自由基,并防止缺氧细胞的进一步损伤。
BACKGROUND: Most of critically ventilated patients with severe hemorrhagic shock experience metabolic acidosis, hypoalbuminemia, electrolyte imbalance, and increased production of free radical. Channa striata has a high content of albumin, an essential binding protein that contributes to homeostasis, and when combined with Moringa oleifera and
Curcuma xanthorrhiza, they act as powerful antioxidants. Administration of C. striata, M. oleifera, and C. xanthorrhiza extract orally may benefit patient with hemodynamic issues, including significant blood loss.
METHODS: A 40-year-old Indonesian woman came to emergency department with decreased consciousness resulting from hemorrhagic shock grade 3 due to prolonged placenta retention for 10 days after delivery of her third child. She had an emergency hysterectomy and was sent to the intensive care unit with a hemoglobin level of 4.2 gr/dL, despite already receiving two bags of packed red blood cells during operation, and she continued with four more bags within her first day in the intensive care unit. The patient was ventilated, was supported by vasopressors, and had a low albumin level of 2.1 gr/dL. Her hemodynamic profile was difficult to stabilize, with persistent gastric residue and periodic urine output less than 1 cc/kg/hour, thereby slowing the ventilator and vasopressor weaning process. Oral supplementation of C. striata, M. oleifera, and C. xanthorrhiza was given in the second day divided in three doses every 6 hours. After the second dose, gastric residue started to subside and disappeared after the third dose. The patient\'s condition improved in the next 24 hours; she was extubated and discharged from the hospital in the fourth day.
CONCLUSIONS: This is the first
case report describing the effect of C. striata, M. oleifera, and C. xanthorrhiza extract in a patient with severe hemorrhagic shock due to a prolonged placenta. Accelerated recovery showed the possibility benefit of C. striata, M. oleifera, and C. xanthorrhiza extract in stabilizing oncotic pressure, neutralizing free radicals, and preventing further damage in hypoxic cells.