背景:利用像雄性猪这样的大型动物模型进行生物力学研究为理解人体关节和组织力学提供了一种经济有效的方法。我们的研究探索了雄性猪窒息关节的骨学和半月板解剖结构,并将其与人类膝关节参数进行了比较。旨在为骨科研究和外科培训提供有价值的参考。
方法:我们检查了60个雄性猪的关节,并分析了它们的半月板和骨骼。解剖是一丝不苟地进行的,使用数字游标卡尺和ImageJ软件进行测量。这些尺寸包括骨形态和半月板宽度,高度,和音量,然后使用未配对的学生t检验进行统计分析。
结果:骨骼和半月板的各种测量表明与人类膝盖具有高度的解剖学相似性。内侧半月板前部宽度为12.545±1.763mm,而外侧半月板为14.99±1.720mm。内侧半月板中间宽度为12.065±1.691mm,与14.375±1.732毫米的外侧半月板相比。内侧半月板的后部宽度为15.25±1.741mm,外侧半月板的后部宽度为16.39±1.662mm。股骨髁间切迹尺寸随年龄增大而变浅,类似于人类膝盖发育中的成熟模式。内侧半月板平均体积4.30±0.13ml,而外侧半月板为5.9±0.29ml。股骨髁长宽比为1.04±0.04(0.95-1.11),胫骨髁的长宽比为0.65±0.02(0.61-0.70),通过数字游标卡尺测量。这些发现具有统计学意义,展示了雄性猪模型在复制人类膝关节力学中的相关性(p<0.05)。
结论:雄性猪窒息关节为膝关节解剖研究提供了一个有效且可接近的模型。我们的研究强调了雄性猪模型在理解人类膝关节生物力学方面的价值,并支持其在骨科研究和训练中的持续使用。这些发现通过提供可靠且解剖学上可比的模型,对推进骨科研究方法和加强外科培训实践具有重要意义。
BACKGROUND: Utilizing large animal model like male pig for biomechanical studies offers a cost-effective approach to understanding human joint and tissue mechanics. Our study explores the osteology and meniscus anatomy of the male porcine stifle joint and compares it to human knee joint parameters, aiming to provide a valuable reference for orthopaedic research and surgical training.
METHODS: We examined 60 male porcine stifle joints and analyzed their menisci and bones. Dissections were meticulously performed, with measurements taken using digital Vernier calipers and ImageJ software. These dimensions included bone morphology and meniscal width, height, and volume, followed by statistical analysis using unpaired Student\'s t-tests.
RESULTS: The various measurements of bones and menisci indicated a high degree of anatomical similarity to human knees. The anterior width of the medial meniscus was 12.545 ± 1.763 mm, while the lateral meniscus was 14.99 ± 1.720 mm. The middle width of the medial meniscus was 12.065 ± 1.691 mm, compared to the lateral meniscus at 14.375 ± 1.732 mm. The posterior width was 15.25 ± 1.741 mm for the medial meniscus and 16.39 ± 1.662 mm for the lateral meniscus. The femoral intercondylar notch dimensions widened and became shallower with age, resembling the maturation patterns seen in human knee development. The average volume of the medial meniscus was 4.30 ± 0.13 ml, while the lateral meniscus was 5.9 ± 0.29 ml. The aspect ratio of the femoral condyles was 1.04 ± 0.04 (0.95-1.11), while the aspect ratio of the tibial condyles was 0.65 ± 0.02 (0.61-0.70), measured via digital Vernier calipers. These findings were statistically significant, showcasing the male porcine model\'s relevance in replicating human knee mechanics (p < 0.05).
CONCLUSIONS: Male porcine stifle joints present a valid and accessible model for knee anatomy research. Our study underscores the value of the male porcine model in understanding human knee joint biomechanics and supports its continued use in orthopaedic research and training. These findings have significant implications for advancing orthopaedic research methodologies and enhancing surgical training practices by providing a reliable and anatomically comparable model.