Chondromyxoid fibroma

软骨粘液样纤维瘤
  • 文章类型: Journal Article
    软骨粘液样纤维瘤(CMF)是一种罕见的软骨肿瘤,占良性骨肿瘤的<1%。我们报告一例颞下颌关节(TMJ)-CMF,涉及翼腭间隙和颅底,并讨论其流行病学,临床特征,和管理。
    一名56岁的妇女由于肿块向上扩展到耳颞部区域而表现出面部不对称和逐渐张口的限制。使用数字技术确定病变的边界并重建正常的关节盂窝,肿瘤切除后,在钛网和髁之间移植颞肌筋膜瓣以重建椎间盘。
    该病例突出了识别TMJ-CMF患者的重要性。
    UNASSIGNED: Chondromyxoid fibroma (CMF) is a rare cartilaginous tumor, accounting for < 1% of benign bone tumors. We report a case of temporomandibular joint (TMJ)-CMF, involving the pterygopalatine space and skull base and discuss its epidemiology, clinical characteristics, and management.
    UNASSIGNED: A 56-year-old woman presented with facial asymmetry and progressive mouth opening restriction due to a mass expanding upwardly to the auriculotemporal region. Using digital techniques to determine the lesion\'s boundary and reconstruct the normal glenoid fossa, the temporalis myofascial flap was transplanted between the titanium mesh and condyle to reconstruct the disc after tumor resection.
    UNASSIGNED: This case highlights the importance of identifying patients with TMJ-CMF.
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  • 文章类型: Case Reports
    软骨粘液样纤维瘤是最罕见的骨肿瘤之一,在成年男性的第二个和第三个十年中最常见。它通常会影响长骨的干is端,尤其是股骨和胫骨。诊断可以对各种肿瘤类型提出鉴别挑战,特别是软骨肉瘤,需要单独管理。我们介绍了一例通过软组织肿胀检测到的胫骨远端软骨粘液样纤维瘤。临床,将讨论流行病学和放射学方面。
    Chondromyxoid fibroma is one of the rarest bone tumours, occurring most frequently in adult men in their second and third decades. It generally affects the metaphysis of long bones, particularly the femur and tibia. Diagnosis can pose differential challenges with various tumor types, particularly chondrosarcoma, requiring separate management. We present a case of chondromyxoid fibroma of the distal tibia detected by soft tissue swelling. Clinical, epidemiological and radiological aspects will be discussed.
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  • 文章类型: Case Reports
    软骨粘液样纤维瘤(CMF)是一种罕见的良性骨性肿瘤,特别是关于其在腰椎区域的发病率。CMF主要表现在椎体,在辅助解剖部位表现出非典型的出现。本报告描述了,据我们所知,第二个记录的CMF实例源自腰椎小关节。本病例提供了腰椎小关节突发性椎管狭窄中CMF的示例,因此,由于通过椎间孔的肿瘤增生,导致下肢的神经系统表现。目前的治疗干预需要手术切除肿瘤并伴有小关节关节固定术,为了实现全面根除肿瘤的目标,改善症状并保护患者的脊柱结构完整性。本研究旨在说明这种罕见肿瘤的临床意义,从而阐明与腰椎小关节CMF相关的诊断难题和治疗复杂性。此外,本研究旨在增加CMF诊断和临床管理的现有知识。
    Chondromyxoid fibroma (CMF) is a rarely documented benign osseous neoplasm, particularly with respect to its incidence in the lumbar spinal region. CMF predominantly manifests in vertebral bodies, exhibiting atypical emergence in ancillary anatomical sites. The present report describes, to the best of our knowledge, the second documented instance of CMF originating from the lumbar facet joint. The present case provides an example of CMF in the lumbar facet joint precipitating spinal canal stenosis, thereby engendering neurological manifestations in the lower extremities due to neoplastic proliferation through the intervertebral foramen. The present therapeutic intervention entailed surgical excision of the neoplasm concomitant with facet joint arthrodesis, with the objective of achieving comprehensive neoplasm eradication, ameliorating the symptomatology and safeguarding the spinal structural integrity of the patient. The present study aimed to illustrate the clinical implications of this rare neoplasm, thereby elucidating the diagnostic quandaries and therapeutic complexities associated with CMF in the lumbar facet joint. In addition, the present study aimed to augment the existing knowledge for the diagnosis and clinical management of CMF.
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  • 文章类型: Case Reports
    软骨粘液样纤维瘤是一种不寻常的,通常位于长骨干phy端区域的良性骨肿瘤。它占所有骨肿瘤的不到1%。它主要表现在男性的第二个和第三个十年。很少,它发生在颅面骨骼的骨骼中。对于小,病灶摘除术和刮治,对于较大的病灶,切除后的是可用的治疗方式.这里,我们介绍了一例下颌骨右侧软骨粘液样纤维瘤的病例,该病例通过手术切除,然后在全身麻醉下进行重建。切除后重建提供了令人满意的结果,尤其是在有大病灶的情况下。软骨粘液样纤维瘤是无症状的,良性,缓慢生长的病变,但可以迅速扩大,并涉及更大的骨面积。因此,早期发现并在适当的时间进行治疗可以降低与病变相关的发病率并提高患者的生活质量。
    Chondromyxoid fibroma is an unusual, benign bone tumour that is usually sited in the metaphyseal region of the long bones. It accounts for less than 1% of all bone tumours. It manifests predominantly in males in their second and third decades of life. Rarely, it occurs in the bones of the craniofacial skeleton. For small, lesions enucleation and curettage and for larger lesions, resection followed by are the treatment modalities available. Here, we present a case of chondromyxoid fibroma with respect to the right side of the mandible which was managed by surgical resection followed by reconstruction under general anaesthesia. Resection followed by reconstruction provides satisfactory outcomes, especially in cases with large lesions. Chondromyxoid fibroma is an asymptomatic, benign, slow-growing lesion but can rapidly expand and involve the greater area of bone. Thus, its detection at an early stage and treatment at the proper time can lead to less morbidity associated with the lesion and improved quality of life of the patient.
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  • 文章类型: Case Reports
    背景:软骨粘液样纤维瘤(CMF)是一种软骨组织的罕见良性肿瘤,可能与其他恶性肿瘤混淆。在颈椎中很少见。
    方法:一名24岁的年轻女性因颈部和肩部疼痛入院。计算机断层扫描,磁共振成像,颈椎X线等影像学检查及实验室相关指标结合术中病理提示患者存在颈椎CMF。我们对椎体和椎间盘进行了全切除,并进行内固定,以同时保持整个脊柱的稳定性。广泛切除的临床结果令人满意。在2年的随访中,患者的症状没有复发。
    结论:CMF是一种良性原发性骨肿瘤,很少位于椎骨中。这些肿瘤的准确初步诊断对于适当的治疗很重要。整块手术切除肿瘤是治疗的基石。
    BACKGROUND: Chondromyxoid fibroma (CMF) is an unusual benign tumour of cartilaginous tissues that may be confused with other malignant tumours. It is rarely seen in the cervical spine.
    METHODS: A 24-year-old young woman was admitted to the hospital because of neck and shoulder pain. Computed tomography, magnetic resonance imaging, X-ray and other imaging examinations of the cervical spine and laboratory-related indicators combined with intraoperative pathology revealed that the patient had cervical CMF. We performed total resection of the vertebral body and intervertebral disc, and internal fixation was performed to simultaneously maintain the stability of the entire spine. The clinical results from extensive resection were satisfactory. At the 2-year follow-up, the patient\'s symptoms had not recurred.
    CONCLUSIONS: CMF is a benign primary bone tumour that is rarely located in the vertebral bone. Accurate initial diagnosis of these tumours is important for appropriate treatment. En bloc surgical resection of the tumour is the cornerstone of treatment.
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  • 文章类型: Case Reports
    跟骨软骨粘液样纤维瘤(CMF)极为罕见。我们报告了一名34岁女性的跟骨CMF病例。她脚痛了一年,在过去的两个月里疼痛加重。病人抱怨由于感到疼痛而跛行。跟骨的CMF采用刮除和植骨治疗。允许患者在手术的第二天动员,并尽可能多地负重。在患者的18个月随访期间没有复发。患者可以无痛苦地进行日常生活中的活动。仔细进行刮治和植骨是治疗跟骨CMF的有效方法。跟骨的CMF可能不像想象的那么罕见,应在鉴别诊断中加以考虑。
    Chondromyxoid fibroma (CMF) of the calcaneus is extremely rare. We report a case of CMF of the calcaneus in a 34-year-old female. She had foot pain for one year and had increased pain for the last two months. The patient complained of limping due to the pain she felt. CMF of the calcaneus was treated with curettage and bone grafting. The patient was allowed to mobilize the very next day of surgery with weight bearing as much as she could tolerate. No recurrence was encountered during the 18-month follow-up of the patient. The patient could perform activities in her daily life painlessly. Carefully performed curettage and bone grafting is an effective treatment method in the treatment of CMF of the calcaneus. CMF in the calcaneus may not be as rare as it is thought, and should be considered in the differential diagnosis.
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  • 文章类型: Case Reports
    背景:软骨粘液样纤维瘤(CMF)是一种罕见的良性骨肿瘤,通常会影响长骨,只有2%的CMF涉及面部骨骼或头骨,到目前为止,zy骨定位极为罕见,只有8例文献报道。
    方法:我们报告了一例88岁患者,在1年左右出现右侧颧骨疼痛性肿胀,数量逐渐增加,计算机断层扫描(CT)扫描显示右zh骨的溶骨性病变,皮质破坏。手术治疗包括使用口腔内方法刮骨术,组织病理学结果有利于CMF的诊断.
    结论:CF是一种罕见的骨肿瘤,占所有骨肿瘤的不到1%,颌面部骨骼很少受到影响,以下颌骨为好发部位,颧骨位置极为罕见。临床表现不典型,放射学,病变通常为溶骨性,边缘清晰。整块切除是黄金标准,一些作者建议采取保守的方法来避免审美和功能后遗症。
    结论:我们报道了一种非常罕见的CF表现,涉及通过保守方法治疗的zy骨。
    BACKGROUND: Chondromyxoid fibroma (CMF) is a rare benign bone tumor that typically affects long bones, only 2% of CMFs involved facial bones or skull, zygomatic localization is extremely rare with only 8 cases reported in literature so far.
    METHODS: We report a case of 88 old years patient with painful swelling in the right zygomatic around 1 year, progressively increasing in volume, Computed tomography (CT) scan showed an osteolytic lesion in the right zygomatic bone with cortical destruction. Surgical management consisted of bone curettage using intra oral approach, the histopahological findings were in favor of the diagnosis of CMF.
    CONCLUSIONS: CF is a rare bone tumor and represents less than 1% of all bone tumors, the maxillofacial bones are rarely affected, with the mandible as a site of predilection, the zygomatic location is extremely rare. The clinical presentation is not typical, radiologically, the lesion is usually osteolytic with well defined margins.En bloc resection is the gold standard, some authors recommand conservative approach to avoid esthetic and functional sequels.
    CONCLUSIONS: We reported a very rare presentation of CF involving zygomatic bone treated by conservative approach.
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  • 文章类型: Case Reports
    软骨粘液样纤维瘤(CMF)是一种罕见的良性肿瘤,占所有良性肿瘤的<2%,占所有骨肿瘤的<1%。它是具有粘液样和纤维成分的软骨肿瘤。由于罕见且与其他良性和恶性肿瘤相似,这种肿瘤的诊断始终具有挑战性。通常,这种病变会影响儿童和年轻人长骨的干phy端。该肿瘤的常见位置在胫骨和腓骨近端和股骨远端的生长板周围。
    一位21岁的男性出现在骨科门诊部,有1年的左髋部疼痛史,在一年前的一次微不足道的下跌之后。患者无法进行剧烈的活动,例如跑步,跳跃,其他体育活动。运动的终端范围是痛苦的。磁共振成像提示囊性病变,累及左侧股骨头颈交界处滑膜衬里。对病灶进行刮除。未发现骨缺损足够大以填充骨移植物。组织病理学检查显示小叶状,粘液样背景上有星状至纺锤形细胞。
    股骨颈下区域的CMF是一种极不寻常的表现。当发生在中年人和罕见的地方时,这可能会引起软骨肉瘤的怀疑。虽然病灶内刮治术后有复发的风险,充分和仔细的刮除和切除病变将足以治疗这些良性病变,预后良好。
    UNASSIGNED: Chondromyxoid fibroma (CMF) is an uncommon benign tumor accounts for <2% of all benign and <1% all bone tumors. It is a cartilage tumor with myxoid and fibrous elements. Because of rarity and resemblance with other benign and malignant tumor, diagnosis of this tumor always remains challenging. Often, this lesion affects metaphysis of long growing bones of children and young adults. Common locations of this tumor are around the growth plate of proximal tibia and fibula and distal femur.
    UNASSIGNED: A 21-year-old male presented to orthopedic outpatient department with a history of the left hip pain for 1 year, following a trivial fall before 1 year. The patient was not able to do heavy strenuous activities such as running, jumping, and other sports activities. Terminal range of movements were painful. Magnetic resonance imaging suggested of cystic lesion involving synovial lining near head-and-neck junction of the left femur. Curettage of the lesion was done. The bone defect was not found to be large enough to be filled with bone graft. Histopathological examination showed lobular pattern with stellate to spindle-shaped cells on the myxoid background.
    UNASSIGNED: CMF of subcapital region of femoral neck is an extremely unusual presentation. When occurring in middle-aged persons and in uncommon locations, this can raise suspicion of chondrosarcoma. Although intralesional curettage has the risk of recurrence in post-operative period, sufficient and careful curettage and excision of lesion will be enough to treat these benign lesions with good prognosis.
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  • 文章类型: Journal Article
    Chondromyxoid fibroma is a rare bone tumor characterized by immature myxoid mesenchymal tissue showing early primitive cartilaginous differentiation. There have been limited case reports describing the cytologic features of chondromyxoid fibroma. Herein, we reported cytologic features of chondromyxoid fibroma on fine-needle aspiration (FNA).
    We performed a retrospective search in our cytopathology and surgical pathology database for cases diagnosed as chondromyxoid fibroma that had corresponding cytology specimens from three medical institutions. All available cytopathology specimens were reviewed.
    Eight cases were retrieved from patients aged 16-77 years (mean, 51 years), and M:F ratio of 1.7:1. Seven tumors (88%) were primary, and most (62%) occurred in flat bones. Cytologic diagnoses were made in 6 cases with cytologic slides not available to review in 1 case. All cases showed metachromatic matrix in the background, while hyaline cartilage fragments were absent. All cases had two cell populations comprising oval to round cells and stellate to spindle cells. The spindle to stellate cells were more commonly embedded in matrix material. Moderate atypia (hyperchromasia and moderate anisonucleosis) was present in 4 cases (80%), while no mitotic figure was present in all cases.
    Our study highlights common cytologic features of chondromyxoid fibroma, including the presence of the spindle or stellate cells embedded in matrix material. Hyaline cartilage is uncommon and, if present, diagnostic considerations should include enchondroma or low-grade chondrosarcoma. A specific cytologic diagnosis primarily using FNA samples can be challenging but possible when evaluated in conjunction with clinical and radiologic data.
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  • 文章类型: Case Reports
    最初描述,1948年,作为一种在组织病理学上可能被误认为是软骨肉瘤的肿瘤,软骨粘液样纤维瘤现在是一个公认的实体。表面型软骨粘液样纤维瘤,然而,仍然是极为罕见的事件。我们介绍了一个55岁女性的案例,经历了5年的右臂疼痛。在假定的胸廓出口综合征治疗失败后,MRI显示在骨膜下位置的肱骨远端骨干的前内侧皮质附近有一个大肿块。用射线照相术进一步表征,CT,还有骨骼扫描,随后进行超声引导活检。尽管组织病理学特征提示软骨粘液样纤维瘤,由于涉及肱骨骨干的非常不寻常的位置,最初的诊断仍然不确定。进行了手术切除,随后的组织病理学分析证实了软骨粘液样纤维瘤的诊断。尽管是一个罕见的实体,在处理扩张性表面骨干病变时,需要在差异中考虑表面型软骨粘液样纤维瘤。
    Initially described, in 1948, as a tumor that could be mistaken with chondrosarcoma at histopathology, chondromyxoid fibroma is now a well-recognized entity. Surface-type chondromyxoid fibroma, however, remains an extremely rare occurrence. We present a case of a 55-year-old woman, who experienced right arm pain for 5 years. After unsuccessful treatment for presumed thoracic outlet syndrome, MRI revealed a large mass abutting the anteromedial cortex of the distal humeral diaphysis in a subperiosteal location. Further characterization was made with radiography, CT, and bone scan, which were followed by ultrasound-guided biopsy. Although histopathologic features were suggestive of chondromyxoid fibroma, the diagnosis remained somewhat uncertain initially due to the very unusual location involving the diaphysis of the humerus. Surgical resection was performed, and subsequent histopathologic analysis confirmed the diagnosis of chondromyxoid fibroma. Despite being a rare entity, surface-type chondromyxoid fibroma would need to be considered in the differential when dealing with expansile surface diaphyseal lesions.
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