背景:叶状肿瘤(PT)是一种罕见的乳腺肿瘤,分为良性,边界线,和恶性。巨型PT,意思是那些尺寸超过十厘米的,甚至更罕见,最常见的是恶性的,并且通常由于高转移潜力而预后不佳。
方法:我们报告了一例55岁的女性,她接受了改良根治术和左腋窝淋巴结清扫术,巨人,左乳房溃疡肿块。组织病理学检查显示恶性叶状肿瘤(MPT)。初次手术后一年多,患者被发现有广泛的胸部和腹膜后转移。
结论:尽管巨型PT并不常见,临床怀疑在快速增长的乳腺肿块患者中应该很高。对英语文献中报道的所有转移性巨大MPT病例的全面审查强调了对适当治疗缺乏共识。在转移灶的情况下,病理学家需要了解以前的病史才能做出明确的诊断。此外,对原发性和转移性肿瘤进行比较组织病理学研究有时是必要的.HIPPOKRATIA2022,26(1):41-45.
BACKGROUND: Phyllodes tumors (PTs) represent a rare type of breast tumor and are classified into benign, borderline, and malignant. Giant PTs, meaning those sized more than ten cm, are even rarer, most commonly malignant, and usually have a dismal prognosis due to the high metastatic potential.
METHODS: We report the
case of a 55-year-old woman who underwent modified radical mastectomy and left axillary lymphadenectomy for a rapidly growing, giant, ulcerated mass of the left breast. Histopathologic examination revealed a malignant phyllodes tumor (MPT). Over one year after the initial surgery, the patient was found to have extensive thoracic and retroperitoneal metastases.
CONCLUSIONS: Although giant PTs are uncommon, clinical suspicion should be high in rapidly growing breast mass patients. A comprehensive review of all metastatic giant MPT cases reported in the English literature emphasizes the lack of consensus regarding appropriate treatment. In the
case of metastatic foci, pathologists need to be aware of the previous history to make a definitive diagnosis. Also, a comparative histopathologic study of the primary and metastatic tumors is sometimes necessary. HIPPOKRATIA 2022, 26 (1):41-45.