Abstract：
Primary breast carcinomas often present as ill-defined, infiltrative lesions which may contain calcifications, whereas metastatic cancers from non-mammary sites are often more well-circumscribed, sharply demarcated from the adjacent breast tissue and are usually not associated with calcifications, although there are exceptions. We report an atypical case of a lady with lung adenocarcinoma with pleural involvement, who presented with diffuse breast swelling with calcifications on imaging from metastatic lung adenocarcinoma, the first of its kind in the literature. We postulate that the pathophysiology of this was due to lymphatic spread of the tumour from the pleura resulting in retrograde lymphovascular congestion of the breast, resulting in swelling and dystrophic calcification.
摘要：
原发性乳腺癌通常表现为不明确，浸润性病变可能含有钙化，而来自非乳腺部位的转移性癌症通常受到更严格的限制，与邻近的乳腺组织有明显的界限，通常与钙化无关，虽然也有例外。我们报告了一个非典型病例，一位患有胸膜受累的肺腺癌的女士，转移性肺腺癌影像学表现为弥漫性乳房肿胀伴钙化，这是文学中的第一个。我们推测，这种病理生理学是由于肿瘤从胸膜的淋巴扩散导致乳房的逆行淋巴血管充血，导致肿胀和营养不良性钙化。
