{Reference Type}: Case Reports
{Title}: Breast metastasis presenting as swelling with calcification - A case report and review of the literature.
{Author}: Linn YL;Tay TKY;Tan EH;Wong JSL;Madhukumar P;
{Journal}: Breast Dis
{Volume}: 41
{Issue}: 1
{Year}: 2022
暂无{DOI}: 10.3233/BD-210035
{Abstract}: Primary breast carcinomas often present as ill-defined, infiltrative lesions which may contain calcifications, whereas metastatic cancers from non-mammary sites are often more well-circumscribed, sharply demarcated from the adjacent breast tissue and are usually not associated with calcifications, although there are exceptions. We report an atypical case of a lady with lung adenocarcinoma with pleural involvement, who presented with diffuse breast swelling with calcifications on imaging from metastatic lung adenocarcinoma, the first of its kind in the literature. We postulate that the pathophysiology of this was due to lymphatic spread of the tumour from the pleura resulting in retrograde lymphovascular congestion of the breast, resulting in swelling and dystrophic calcification.