Biliary tract diseases

胆道疾病
  • 文章类型: Journal Article
    背景:当孕妇出现非产科病理时,照顾他们的医生可能不确定最佳管理策略。本指南的目的是为患有常见手术病理(包括阑尾炎)的孕妇制定循证建议。胆道疾病,和炎症性肠病(IBD)。
    方法:美国胃肠和内窥镜外科医师协会(SAGES)指南委员会召集了一个工作组来解决这些问题。该小组提出了五个关键问题,并完成了文献的系统回顾和荟萃分析。然后,专家小组开会,根据建议评估的等级形成基于证据的建议,发展,和评价方法。当现有证据被认为不充分时,就利用了专家意见。
    结果:专家小组同意了十项关于阑尾炎管理的建议,胆道疾病,怀孕期间的IBD。
    结论:有条件的建议支持阑尾切除术而不是非手术治疗阑尾炎,腹腔镜阑尾切除术优于开腹阑尾切除术,腹腔镜胆囊切除术优于胆道疾病和急性胆囊炎的非手术治疗。根据专家意见,该小组还建议在妊娠晚期手术或非手术治疗除急性胆囊炎以外的胆道疾病,内镜逆行胰胆管造影术而非胆总管探查术治疗有症状的胆总管结石,在妊娠和非妊娠IBD患者中应用相同的紧急手术干预标准,对需要紧急手术治疗IBD的妊娠患者采用开放而非微创的方法,并在具有IBD专业知识的中心以多学科的方式管理患有活动性IBD耀斑的孕妇。
    BACKGROUND: When pregnant patients present with nonobstetric pathology, the physicians caring for them may be uncertain about the optimal management strategy. The aim of this guideline is to develop evidence-based recommendations for pregnant patients presenting with common surgical pathologies including appendicitis, biliary disease, and inflammatory bowel disease (IBD).
    METHODS: The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Guidelines Committee convened a working group to address these issues. The group generated five key questions and completed a systematic review and meta-analysis of the literature. An expert panel then met to form evidence-based recommendations according to the Grading of Recommendations Assessment, Development, and Evaluation approach. Expert opinion was utilized when the available evidence was deemed insufficient.
    RESULTS: The expert panel agreed on ten recommendations addressing the management of appendicitis, biliary disease, and IBD during pregnancy.
    CONCLUSIONS: Conditional recommendations were made in favor of appendectomy over nonoperative treatment of appendicitis, laparoscopic appendectomy over open appendectomy, and laparoscopic cholecystectomy over nonoperative treatment of biliary disease and acute cholecystitis specifically. Based on expert opinion, the panel also suggested either operative or nonoperative treatment of biliary diseases other than acute cholecystitis in the third trimester, endoscopic retrograde cholangiopancreatography rather than common bile duct exploration for symptomatic choledocholithiasis, applying the same criteria for emergent surgical intervention in pregnant and non-pregnant IBD patients, utilizing an open rather than minimally invasive approach for pregnant patients requiring emergent surgical treatment of IBD, and managing pregnant patients with active IBD flares in a multidisciplinary fashion at centers with IBD expertise.
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  • 文章类型: Journal Article
    经内镜逆行胰胆管造影术(ERCP)逐步成为儿童胆胰疾病的重要诊治手段。我国儿童ERCP临床应用尚处于起步阶段,临床经验有待于进一步积累,应用技术需要进一步规范。中华医学会儿科学分会消化学组、国家儿童健康与疾病临床医学研究中心儿童消化疾病诊治协同创新联盟及中华儿科杂志编辑委员会牵头组织相关专家制订了“儿童经内镜逆行胰胆管造影术临床应用管理规范专家共识(2024)”,旨在规范儿童ERCP的临床应用和技术推广,减少或避免并发症,提高儿童胆胰疾病的诊疗水平。.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    美洲的肝胰胆管(HPB)奖学金培训包括3种不同课程的独特途径:通过外科肿瘤学会(SSO)获得的外科肿瘤奖学金,通过美国移植外科学会(ASTS)获得的腹部移植外科奖学金,和HPB奖学金通过美洲肝-胰腺-胆道协会(AHPBA)。我们的目标是在HPB外科医生中建立泛美共识,外科肿瘤学家,腹部移植外科医生,和普通外科住院医师计划主任(GSPDs)关于HPB奖学金的核心知识课程,并确定适合HPB研究金以外的普通外科住院医师和亚专科的主题。
    使用3轮修改的Delphi过程。基线声明是由AHPBA的教育和培训委员会制定的,与SSO代表合作,ASTS,和GSPD。专家小组,由3个社团的成员和GSPD组成,以5分的李克特量表对陈述进行评级,并建议编辑或添加新的陈述。当Cronbach的alpha值≥0.8且≥80%的小组同意纳入时,最终课程中包含了一项声明。
    第一轮的应答率是100%,第二轮和第三轮为98%。138项提议的陈述中有89项包含在最终的HPB研究金课程中。除HPB研究金之外的普通外科住院医师和亚专科课程包括50和29个陈述,分别。
    通过改进的德尔菲法,达成了关于HPB奖学金课程核心知识的跨国共识。该核心课程可用于标准化美洲不同途径的HPB奖学金培训。
    Hepatopancreatobiliary (HPB) Fellowship training in the Americas consists of 3 distinctive routes with variable curricula: Surgical Oncology Fellowship via the Society of Surgical Oncology (SSO), Abdominal Transplant Surgery Fellowship via the American Society of Transplant Surgeons (ASTS), and HPB Fellowship via the Americas Hepato-Pancreato-Biliary Association (AHPBA). Our objective was to establish a pan-American consensus among HPB surgeons, surgical oncologists, abdominal transplant surgeons, and general surgery residency program directors (GSPDs) on a core knowledge curriculum for HPB fellowship, and to identify topics appropriate for general surgery residency and subspecialty beyond HPB fellowship.
    A 3-round modified Delphi process was used. Baseline statements were developed by the Education and Training Committee of the AHPBA, in collaboration with representatives of the SSO, ASTS, and GSPDs. The expert panel, consisting of members of the 3 societies together with GSPDs, rated the statements on a 5-point Likert scale and suggested editing or adding new statements. A statement was included in the final curriculum when Cronbach\'s alpha value was ≥ 0.8 and ≥ 80% of the panel agreed on inclusion.
    The response rate was 100% for the first round, and 98% for the second and third rounds. Eighty-nine of 138 proposed statements were included in the final HPB fellowship curriculum. Curricula for general surgery residency and subspecialty beyond HPB fellowship included 50 and 29 statements, respectively.
    A multinational consensus on core knowledge for an HPB fellowship curriculum was achieved via the modified Delphi method. This core curriculum may be used to standardize HPB fellowship training across different pathways in the Americas.
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  • 文章类型: Journal Article
    内镜逆行胰胆管造影术(ERCP)是在1970年代首次报道的。从那以后,ERCP已成为诊断和治疗各种胆胰疾病不可或缺的方法。中国ERCP指南的主要目的是准确定义ERCP的临床适应症。在本准则中,所有建议均基于综述的研究,并根据GRADE标准的支持证据强度进行分级.ERCP特别适用于治疗由胆总管结石和其他良性或恶性疾病引起的胆道梗阻患者。同时,可以用ERCP诊断和治疗各种良性或胰腺疾病。塑料或金属胆道和胰管支架主要用于建立阻塞的胆管或胰管的通畅性。最后但并非最不重要的,充分了解ERCP的潜在并发症非常重要。早期识别和立即处理不良事件对于降低手术相关的发病率和死亡率至关重要。
    Endoscopic retrograde cholangiopancreatography (ERCP) was reported for the first time in 1970s. Since then, ERCP has become an indispensable procedure in the diagnosis and management of a variety of biliary and pancreatic disorders. The main purpose of Chinese ERCP guideline is to precisely define the clinical indications of ERCP. In this guideline, all recommendations were based on reviewed studies and graded on the strength of supporting evidence by GRADE criteria. ERCP is particularly appropriate in the management of patients with biliary obstruction caused by choledocholithiasis and other benign or malignant disorders. Meanwhile, a variety of benign or pancreatic disorders can be diagnosed and treated with ERCP. Plastic or metal biliary and pancreatic stents are primarily used to establish patency of an obstructed bile or pancreatic duct. Last but not least, it is very important to fully understand the potential complications of ERCP. Early recognition and immediate management of adverse events are critical to reduce procedure related morbidity and mortality.
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  • 文章类型: Letter
    直到现在,对于先天性胆道扩张(CBD)尚无实用的临床指南.在这篇评论文章中,日本先天性胆道扩张研究小组(JSCBD)建议建立CBD的临床实践指南。因为基于证据的文献相对较少,我们决定根据专家的共识制定指导方针,使用医学文献作为参考。负责指南的编辑委员会成员总共考虑了20个临床问题(CQs)。CQ包括CBD的不同方面:(1)概念和病理学(三个CQ);(2)诊断(六个CQ);(3)胰胆管并发症(三个CQ);治疗和预后(八个CQ)。CQ的每个陈述和评论均由准则委员会成员做出。CQ在由CBD编辑委员会和指南评估委员会成员审查后最终获得批准。创建这些指南是为了在CBD管理的临床实践中提供帮助;他们的内容侧重于临床效用,它们包括有关CBD的一般信息,以使这种疾病得到更广泛的认可。
    Until now, there have been no practical clinical guidelines for congenital biliary dilatation (CBD). In this review article, the Japanese Study Group on Congenital Biliary Dilatation (JSCBD) propose to establish clinical practice guidelines for CBD. Because the evidence-based literature is relatively small, we decided to create guidelines based on the consensus of experts, using the medical literature for reference. A total of 20 clinical questions (CQs) were considered by the members of the editorial committee responsible for the guidelines. The CQs included the distinct aspects of CBD: (1) Concepts and Pathology (three CQs); (2) Diagnosis (six CQs); (3) Pancreaticobiliary Complications (three CQs); Treatments and Prognosis (eight CQs). Each statements and comments for CQs were made by the guidelines committee members. CQs were finally approved after review by members of the editorial committee and the guidelines evaluation board of CBD. These guidelines were created to provide assistance in the clinical practice of CBD management; their contents focus on clinical utility, and they include general information on CBD to make this disease more widely recognized.
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  • 文章类型: Journal Article
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  • 文章类型: Comparative Study
    OBJECTIVE: We retrospectively analyzed incisional hernia (IH) outcomes of liver transplant (LT) vs. hepatopancreaticobiliary (HPB) cases sharing the same incision.
    METHODS: IH repair patients with a history of LT were compared with those with HPB surgical history sharing the same type of incision and using the European Hernia Society classification and nomenclature for reporting outcome.
    RESULTS: Eighty-two patients (27 HPB and 55 LT) between February 2001 and February 2014 were analyzed. Baseline demographics showed that the LT group had more diabetes and steroid use, but were less physical active. Outcomes showed no differences in wound complication, SSI rate, and recurrence rate (recurrence rate of 11.1% and 16.4% for HPB and LT, respectively). Multivariate analysis showed longer operating time to be a risk factor for both wound complication and SSI. M-tor inhibitor use was an additional risk factor for SSI. Interval to recurrence was significant longer in the LT group (35 vs. 61 months). Cox analysis showed steroid use, immunosuppression and not using a synthetic mesh as risk factors for recurrence.
    CONCLUSIONS: Incisional hernia repair with synthetic mesh after liver transplantation does not result in more wound complications, SSI, and recurrences, when compared to patients without immunosuppression.
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  • 文章类型: Journal Article
    OBJECTIVE: To provide consensus statements on the use of per-oral cholangiopancreatoscopy (POCPS).
    METHODS: A workgroup of experts in endoscopic retrograde cholangiopancreatography (ERCP), endosonography, and POCPS generated consensus statements summarizing the utility of POCPS in pancreaticobiliary disease. Recommendation grades used validated evidence ratings of publications from an extensive literature review.
    RESULTS: Six consensus statements were generated: (1) POCPS is now an important additional tool during ERCP; (2) in patients with indeterminate biliary strictures, POCS and POCS-guided targeted biopsy are useful for establishing a definitive diagnosis; (3) POCS and POCS-guided lithotripsy are recommended for treatment of difficult common bile duct stones when standard techniques fail; (4) in patients with main duct intraductal papillary mucinous neoplasms (IPMN) POPS may be used to assess extent of tumor to assist surgical resection; (5) in difficult pancreatic ductal stones, POPS-guided lithotripsy may be useful in fragmentation and extraction of stones; and (6) additional indications for POCPS include selective guidewire placement, unexplained hemobilia, assessing intraductal biliary ablation therapy, and extracting migrated stents.
    CONCLUSIONS: POCPS is important in association with ERCP, particularly for diagnosis of indeterminate biliary strictures and for intra-ductal lithotripsy when other techniques failed, and may be useful for pre-operative assessment of extent of main duct IPMN, for extraction of difficult pancreatic stones, and for unusual indications involving selective guidewire placement, assessing unexplained hemobilia or intraductal biliary ablation therapy, and extracting migrated stents.
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  • 文章类型: Journal Article
    OBJECTIVE: Several randomized controlled trials studied the role of endoscopic retrograde cholangiopancreaticography (ERCP) and endoscopic sphincterotomy (ES) in acute biliary pancreatitis (ABP). No study assessed whether these trials resulted in international consensus in published meta-analyses and treatment guidelines.
    METHODS: A systematic review, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, of meta-analyses and guidelines on ERCP in ABP was performed in PubMed until August 2011.The methodological quality of the meta-analysis and guidelines was assessed by a validated quality assessment tool.
    RESULTS: Eight meta-analyses and 12 guidelines fulfilled the inclusion criteria. There is consensus that ERCP is indicated in case of ABP with coexistent cholangitis and/or persistent cholestasis. By exception of the first meta-analysis, all included studies disapproved early ERCP in predicted mild ABP. Consensus is lacking regarding the role of early ERCP in predicted severe ABP, as 3 meta-analyses and 1 guideline do not advice this strategy. Routine early ERCP in predicted severe ABP is recommended in 7 of the 11 guidelines.
    CONCLUSIONS: There is consensus in guidelines and meta-analyses that ERCP/ES is indicated in patients with ABP and coexisting cholangitis and/or persistent cholestasis. Consensus is lacking on the role of routine early ERCP/ES in patients with predicted severe ABP.
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