背景:在分析腺样体扁桃体肥大与颅面形态之间的关系时,研究人员通常将肥大的腺样体和扁桃体视为一个整体。尚不清楚咽淋巴组织的不同扩大部位是否与多种颅面亚型相关。我们假设颅面亚型与肥大的腺样体和扁桃体的不同位置相关。
方法:从466名儿童(171名男孩和295名女孩,年龄12.27±2.69岁)。根据咽部淋巴组织肿大部位不同分为4组:腺样体肥大组(AG,n=126),扁桃体肥大组(TG,n=59),腺样体扁桃体肥大组(ATG,n=69)和对照组(CG,n=212)。研究了五个常用的头颅测量角度:SNA(Sella-Nasion-PointA),SNB(Sella-Nasion-PointB),ANB(A点-B点),下颌平面角(MP/SN)和Y轴角(SGn/FH)。
结果:与对照组相比,孤立性扁桃体肥大的儿童与SNA(非标准化回归系数B=1.38,p=0.009)和SNB(B=1.99,p=0.001)增加相关。然而,孤立性腺样体肥大的儿童与SNB降低相关(B=-0.94,p=0.036),增加ANB(B=0.74,p=0.014)和增加MP/SN(B=2.22,p<0.001)。同样,腺样体扁桃体肥大与SNB降低相关(B=-1.36,p=0.015),增加ANB(B=1.35,p<0.001),增加MP/SN(B=2.64,p=0.001)。
结论:孤立的腺样体肥大与下颌骨后移相关,增加的上颌下颌矢状差异,和增加的下颌平面角。孤立的扁桃体肥大与上颌和下颌前突有关。腺样体扁桃体肥大未显示上述两者的重叠颅面模式,但显示与孤立的腺样体肥大相同的颅面模式。
When analyzing the relationship between adenotonsillar hypertrophy and craniofacial morphology, researchers generally regarded hypertrophied adenoids and tonsils as a whole. It remains unclear whether different enlarged sites of pharyngeal lymphoid tissue would correlate with multiple craniofacial subtypes. We hypothesized there would be craniofacial subtypes correlated with different locations of hypertrophied
adenoid and tonsil.
Lateral cephalometric radiographs were obtained from 466 children (171 boys and 295 girls, aged 12.27 ± 2.69 years). They were divided into four groups according to different sites of enlarged pharyngeal lymphoid tissue:
adenoid hypertrophy group (AG, n = 126), tonsillar hypertrophy group (TG, n = 59), adenotonsillar hypertrophy group (ATG, n = 69) and control group (CG, n = 212). Five commonly used angles for cephalometric measurements were investigated: SNA (Sella-Nasion-Point A), SNB (Sella-Nasion-Point B), ANB (Point A-Nasion-Point B), mandibular plane angle (MP/SN) and Y-axis angle (SGn/FH).
Children with isolated tonsillar hypertrophy correlated with increased SNA (unstandardized regression coefficient B = 1.38, p = 0.009) and SNB (B = 1.99, p = 0.001) compared with controls. However, children with isolated
adenoid hypertrophy correlated with decreased SNB (B=-0.94, p = 0.036), increased ANB (B = 0.74, p = 0.014) and increased MP/SN (B = 2.22, p < 0.001). Similarly, children with adenotonsillar hypertrophy correlated with decreased SNB (B=-1.36, p = 0.015), increased ANB (B = 1.35, p < 0.001) and increased MP/SN (B = 2.64, p = 0.001).
Isolated
adenoid hypertrophy correlated with a retrognathic mandible, an increased maxillo-mandibular sagittal discrepancy, and an increased mandibular plane angle. Isolated tonsillar hypertrophy correlated with maxillary and mandibular protrusion. Adenotonsillar hypertrophy did not show a superimposed craniofacial pattern of the above two but showed the same craniofacial pattern as isolated
adenoid hypertrophy.