Adenoid

腺样体
  • 文章类型: Journal Article
    毛状息肉,被认为是一种非常不寻常的先天性咽部异常,许多学者认为是从胚胎阶段的外胚层和中胚层产生的。这些生长物通常具有梨或香肠的形状,被带束,它们的尺寸范围在0.5到6厘米之间。它们通常为灰白色或粉红色。本文讨论了一名12岁的女性,她在鼻咽壁左侧的咽鼓管入口处生长,通过颈部软组织的计算机断层扫描扫描确定;怀疑是源自左咽鼓管的毛状息肉。通过病理证实了毛状息肉的诊断。咽鼓管上的多毛息肉,在这种情况下,表现出不规则的形状,底部很宽,使它看起来像腺样体;因此,增加其被误诊为残余腺样组织的风险。
    Hairy polyps, considered a highly unusual congenital anomaly of the pharynx, are believed by many scholars to arise from the ectoderm and mesoderm during the embryonic stage. These growths often have a pear or sausage shape, are pedunculated, and their size ranges between 0.5 and 6 cm. They are typically grayish white or pink in color. This article discusses a 12-year-old female who had a growth at the Eustachian tube\'s entrance on the left side of the nasopharyngeal wall, as identified by a computed tomography scan of the neck soft tissue; it was suspected to be a hairy polyp originating from the left Eustachian tube. The diagnosis of a hairy polyp was confirmed through pathology. The hairy polyp at the Eustachian tube, in this case, showed an irregular form with a wide base, making it look similar to an adenoid; thus, increasing the risk of it being misdiagnosed as residual adenoid tissue.
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  • 文章类型: Case Reports
    腺样鳞状细胞癌是鳞状细胞癌的一种罕见变异型。主要报道在头部和颈部的阳光照射区域。在文学中,鳞状细胞癌的腺样体变体在嘴唇和舌头中被报道。记录的颊粘膜病例很少。在这个案例报告中,我们描述了鳞状细胞癌的腺样体变体,这是一种罕见的癌症。
    Adenoid squamous cell carcinoma is a rare variant of squamous cell carcinoma. It is mainly reported in the sun-exposed areas of the head and neck. In literature, adenoid variants of squamous cell carcinoma are reported in the lip and tongue. Documented cases of buccal mucosa are very few. In this case report, we describe an adenoid variant of squamous cell carcinoma, which is an unusual presentation of a rare carcinoma.
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  • 文章类型: Journal Article
    简介:牙源性肿瘤包括一组异质性病变,范围从错构瘤性病变到恶性肿瘤。组织学表现的显着变化可能会误导其准确的诊断和分类。成釉细胞瘤通常很容易理解并且易于诊断,但是自从Broca在1867年对牙源性肿瘤进行分类以来,分类系统一直在变化。多年来,它已被世界卫生组织修改,有许多补充和遗漏。这种动态变化是基于分子和遗传研究的结果和结论,最后一次修改是在2017年。病例报告:我们介绍了2例32岁和60岁女性报告面部肿胀,显示存在明显的组织病理学发现,并被诊断为成釉细胞瘤伴有牙样或腺样成釉细胞瘤。文献检索显示缺乏不同形式的成釉细胞瘤,这些成釉细胞瘤显示形成导管样结构和牙质。结论:由于缺乏相关研究和对患者的随访,生物学行为仍未被探索,因此强调此类病例很有趣。了解新实体的发病机制和组织病理学特征将有助于及时诊断,治疗计划和扩大病变范围。
    在线版本包含补充材料,可在10.1007/s12070-023-03534-6获得。
    Introduction: Odontogenic tumors encompass a heterogeneous group of lesions that range from hamartomatous lesions to malignancy. Considerable variation in histologic presentation can mislead their accurate diagnosis and categorization. Ameloblastoma is generally well understood and is easy to diagnose but there has been a constant change in the classification systems ever since Broca classified odontogenic tumors in the year 1867. Over the years, it has been modified by the World Health Organization with many additions and omissions. This dynamic change is based on the result and conclusions of molecular and genetic studies with the last modification in 2017. Case Report: We present two cases of females aged 32 and 60 years who reported with facial swellings, revealed the presence of distinct histopathological findings and were diagnosed as ameloblastoma with dentinoid or adenoid ameloblastoma. Literature search revealed dearth of distinct forms of ameloblastoma that show the formation of duct like structures and dentinoid. Conclusion: It is interesting to highlight such cases as the biological behavior is still unexplored due to paucity of relevant studies and follow up of patients. Understanding the pathogenesis and the histopathological characteristics of the newer entities will enable the prompt diagnosis, treatment plan and expanding the spectrum of the lesions.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-023-03534-6.
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    文章类型: Case Reports
    UNASSIGNED: Primary tuberculosis (TB) of the oropharynx and nasopharynx is an extremely rare form of extra-pulmonary TB in children. Primary tuberculosis occurs more likely secondary to pulmonary TB and is more common in immunocompromised patients.
    UNASSIGNED: We reported the case of a young male presented with the symptoms of non-specific chronic adenotonsillitis, mild obstructive sleep apnoea, and cervical lymphadenopathy. Subsequently, he underwent adenotonsillectomy and excision of the cervical lymph node with the tissue specimens came back strongly positive for TB. Then, he started using antituberculous medication and recovered well.
    UNASSIGNED: The authors would like to highlight this rare clinical entity in which accurate diagnosis is essential for complete treatment.
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  • 文章类型: Case Reports
    Primary tumors of the brachial plexus are rare. Most are benign and characterized as Schwannoma and neurofibroma, whereas malignant peripheral nerve sheath tumors are less common. Here, we report a rare case of primary embryonal carcinoma in the brachial plexus.
    A 17-yr-old male presented with a 3-mo history of a mass growing in the left supraclavicular region over the middle part of the clavicle. Magnetic resonance imaging revealed a well-defined mass (diameter 2.5 cm) straddling the brachial plexus. After surgical resection, and the mass was histologically confirmed to be an embryonal carcinoma.
    Primary embryonal carcinoma in the brachial plexus has not been reported previously. This case highlights the importance of considering the possibility that some primary brachial plexus tumors may be malignant and should be treated promptly.
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  • 文章类型: Journal Article
    背景:先前已经描述了次级淋巴器官中的正常胸腺细胞前体。重要的是通过流式细胞术识别正常胸腺细胞前体,以区分它们与T细胞淋巴细胞白血病。
    方法:一名3岁男孩在同种异体心脏移植2年后接受了腺样体切除术以排除移植后淋巴增生性疾病。微观,免疫组织化学,进行腺样体的流式细胞术分析。
    结果:通过流式细胞术,在1.0%的淋巴细胞中观察到CD45(dim)/CD7(bright)/CD3-细胞群。这些细胞表达CD10,部分CD34,并显示获得CD4,然后获得CD8。在更亮的CD45+淋巴细胞中,鉴定了CD3-/CD4+/CD8+胸腺细胞群和类似大小的CD4+/CD8+细胞群,其表现出获得低密度CD3.通过免疫染色,在卵泡间区域发现了TdT+/CD1a+/CD4+/CD8+T细胞簇.与正常胸腺相比,腺样体组织中的胸腺细胞缺乏经典的CD4xCD8翼状分化曲线,但显示出正常的早期前体模式。
    结论:腺样体胸腺细胞与胸腺和胸腺瘤有相似的分化模式。然而,在胸腺外分化的胸腺细胞中,常见的胸腺细胞分化的典型翼状模式可能并不明显。早期胸腺细胞前体抗原获取谱的识别对于正确解释可能是至关重要的。©2017国际临床细胞计数学会。
    BACKGROUND: Normal thymocyte precursors in secondary lymphoid organs have previously been described. It is important to recognize normal thymocyte precursors by flow cytometry to differentiate them from T-cell lymphoblastic leukemia.
    METHODS: A 3-year-old boy status 2 years post-allogenic cardiac transplant underwent adenoidectomy to exclude post-transplant lymphoproliferative disorder. Microscopic, immunohistochemical, and flow cytometry analyses of the adenoid were performed.
    RESULTS: By flow cytometry, a population of CD45+(dim)/CD7+(bright)/CD3- cells were observed at 1.0% of lymphocytes. These cells expressed CD10, partial CD34, and exhibited acquisition of CD4 followed by CD8. Within the brighter CD45+ lymphocytes, a population of CD3-/CD4+/CD8+ thymocytes and a similarly sized population of CD4+/CD8+ cells exhibiting acquisition of low-density CD3 were identified. By immunostaining, clusters of TdT+/CD1a+/CD4+/CD8+ T-cells were identified in the interfollicular areas. Compared to normal thymus, thymocytes in the adenoid tissue lacked the classic CD4xCD8 winged differentiation profile but showed a normal early precursor pattern.
    CONCLUSIONS: Thymocytes in adenoid show a similar differentiation pattern to thymus and thymoma. However, the classic winged pattern of common thymocyte differentiation may not be readily apparent in thymocytes differentiating outside of the thymus. Recognition of the early thymocyte precursor antigen acquisition profile can be crucial to correct interpretation. © 2017 International Clinical Cytometry Society.
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  • 文章类型: Case Reports
    Normal thymocyte precursors in secondary lymphoid organs have previously been described. It is important to recognize normal thymocyte precursors by flow cytometry to differentiate them from T-cell lymphoblastic leukemia.
    A 3-year-old boy status 2 years postallogenic cardiac transplant underwent adenoidectomy to exclude post-transplant lymphoproliferative disorder. Microscopic, immunohistochemical, and flow cytometry analyses of the adenoid were performed.
    By flow cytometry, a population of CD45+(dim)/CD7+(bright)/CD3- cells were observed at 1.0% of lymphocytes. These cells expressed CD10, partial CD34 and exhibited acquisition of CD4 followed by CD8. Within the brighter CD45+ lymphocytes, a population of CD3-/CD4+/CD8+ thymocytes and a similarly sized population of CD4+/CD8+ cells exhibiting acquisition of low-density CD3 were identified. By immunostaining, clusters of TdT+/CD1a+/CD4+/CD8+ T-cells were identified in the interfollicular areas. Compared to normal thymus, thymocytes in the adenoid tissue lacked the classic CD4xCD8 winged differentiation profile but showed a normal early precursor pattern.
    Thymocytes in adenoid show a similar differentiation pattern to thymus and thymoma. However, the classic winged pattern of common thymocyte differentiation may not be readily apparent in thymocytes differentiating outside of the thymus. Recognition of the early thymocyte precursor antigen acquisition profile can be crucial to correct interpretation. © 2017 International Clinical Cytometry Society.
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  • 文章类型: Case Reports
    Acantholytic squamous cell carcinoma is a well-defined variant of squamous cell cancer in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular microscopic pattern. It usually presents as a nodule with various colors, and it is accompanied by scaling, crusting, and ulceration on the sun-exposed areas of older aged individuals. Histologically, the tumor consists of a nodular, epidermal-derived proliferation that forms island-like structures. At least focally or sometimes extensively, the tumor cells shows a loss of cohesion within the central gland-like or tubular spaces. This tumor resembles the structure of eccrine neoplasms, but it is negative for dPAS, CEA and mucicarmine and it is only positive for EMA and cytokeratins. Herein we report a case of acantholytic squamous cell carcinoma that occurred on the face of an 82-year-old woman.
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  • 文章类型: Journal Article
    OBJECTIVE: To study and review the short- and long-term effects of intranasal steroids on obstructive adenoids.
    METHODS: In this prospective cohort study, 19 children previously treated with mometasone furoate for 3 months were contacted at 3, 6 and 12 months after cessation of treatment. Main outcome measures included: change in severity of nasal obstruction, allergic rhinitis and obstructive symptoms. A systematic review of literature was also performed.
    RESULTS: By one year, 25 per cent of patients required adenoidectomy; the remaining children had no significant change in clinical score (p = 0.464), obstruction severity (p = 0.191) or allergic symptoms (p = 0.284). Fourteen pertinent studies were identified; all but one study showed improvement in the patients\' symptoms and/or degree of obstruction. Two studies with follow up reaching 25 months showed positive effects.
    CONCLUSIONS: The short-term positive effect of some intranasal steroids on obstructive adenoids seems to persist in a significant number of patients after the cessation of treatment.
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  • 文章类型: Case Reports
    Primary liver cancer is uncommon and is generally classified as hepatocellular carcinoma (HCC), bile duct carcinoma, neuroendocrine (or carcinoid) tumor, and mesenchymal tumor (sarcoma). Here we describe the gross and histopathology characteristics of a rare HCC in a captive Arabian sand cat (Felis margarita harrisoni) held at Al Ain Zoo, United Arab Emirates. The description of this case in the Arabian sand cat adds to the current knowledge of hepatocellular carcinoma in captive nondomestic felids.
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