METHODS: This paper reports the trajectory and therapeutic regimen documentation of a primigravida with APSN. The APSN was discovered in a primigravida woman aged 26 years at 11 weeks of gestation. The initial therapy regimen consists of daily administration of prednisone 10 mg, hydroxychloroquine 200 mg, dapparin 5000 IU, and aspirin 50 mg. At a gestational age of 20 + 3 weeks, the dosage of dapparin was modified to 5000 IU/other day, along with a significant rise in urinary protein level seen at 30 + 3 weeks of gestational age. The initial dosage of dapanin sodium was renewed. The patient delivered at 38 + 3 weeks of gestation without other complications.
CONCLUSIONS: It is imperative to acknowledge that altering the dosage and administration of medication should not be done haphazardly during pregnancy.
方法:本文报道了使用APSN的primigravida的轨迹和治疗方案文件。APSN是在妊娠11周时26岁的初产妇中发现的。初始治疗方案包括每天给药泼尼松10mg,羟氯喹200毫克,dapparin5000IU,阿司匹林50毫克。胎龄为20+3周,dapparin的剂量被修改为5000IU/另一天,在胎龄30+3周时,尿蛋白水平显着升高。达帕宁钠的初始剂量被更新。患者在妊娠38+3周时分娩,无其他并发症。
结论:必须承认,在怀孕期间不应随意改变药物的剂量和给药方式。