{Reference Type}: Case Reports
{Title}: Antiphospholipid Syndrome Nephropathy Occurs in Pregnancy: A Case Report.
{Author}: Ji C;Wang Y;Zhai X;Ji G;
{Journal}: Am J Reprod Immunol
{Volume}: 92
{Issue}: 2
{Year}: 2024 Aug
{Factor}: 3.777
{DOI}: 10.1111/aji.13906
{Abstract}: <B>OBJECTIVE: </B>This paper presents an analysis of the pregnancy trajectory and therapeutic regimen documentation of a primigravida with APSN. It aims at communicating the therapeutic approach and preventive measures for APSN in pregnancy.<BR><B>METHODS: </B>This paper reports the trajectory and therapeutic regimen documentation of a primigravida with APSN. The APSN was discovered in a primigravida woman aged 26 years at 11 weeks of gestation. The initial therapy regimen consists of daily administration of prednisone 10 mg, hydroxychloroquine 200 mg, dapparin 5000 IU, and aspirin 50 mg. At a gestational age of 20 + 3 weeks, the dosage of dapparin was modified to 5000 IU/other day, along with a significant rise in urinary protein level seen at 30 + 3 weeks of gestational age. The initial dosage of dapanin sodium was renewed. The patient delivered at 38 + 3 weeks of gestation without other complications.<BR><B>CONCLUSIONS: </B>It is imperative to acknowledge that altering the dosage and administration of medication should not be done haphazardly during pregnancy.