PDF(Pubmed)
Abstract：
UNASSIGNED: Determine the effects of a multifactorial lifestyle intervention on physical activity (PA), BMI and health-related quality of life (QoL) in obese and overweight adolescents.
UNASSIGNED: Nine schools in India were clustered randomly in a 12-month study with students allocated to a multifactorial intervention (MFI), or exercise only (EX) or control (CON) group. Participants were adolescents aged 11-16 years (n=671). In the MFI group, adolescents and their parents received lifestyle education using a validated booklet combined with a PA intervention for school students. The EX group received school-based PA only; the CON group continued regular activities. Primary outcomes were PA levels measured with the PAQ-A, and BMI; the secondary outcome was health-related QoL. A linear regression statistical model was used to analyse time, group effects and interactions, with Bonferroni correction for within-group differences at baseline (T0) and at 12-weeks (T1) (post-intervention), 6-month (T2) and 12-month (T3) follow-ups.
UNASSIGNED: Significant time and group effects observed for all groups with PA scores (p<0.001), with MFI group having largest increase in PA; with BMI (p<0.001) and MFI showing the least gain in BMI; and HRQOL (p<0.001), with MFI group showing greatest improvement in scores. There were significant increases in PA at T1 and T3 time-points with the EX group, and at T3 time-point only for MFI and CON, with MFI group showing largest increase in HRQOL scores. BMI increased significantly for all groups at T2 (MFI p=0.001, EX p<0.001) and T3 (p<0.001), while HRQOL increased significantly for both MFI and EX at both follow-ups (p<0.001).
UNASSIGNED: School-based lifestyle MFI was more effective for improving PA, lifestyle behaviours and HRQOL than exercise alone for adolescents, although BMI was not reduced. MFI with PA could be an effective school-based approach for behaviour modification but BMI has limitations for measuring body composition changes.
UNASSIGNED: CTRI/2019/04/018834 (30/04/2019).
UNASSIGNED: Nine schools in India were clustered randomly in a 12-month study with students allocated to a multifactorial intervention (MFI), or exercise only (EX) or control (CON) group. Participants were adolescents aged 11-16 years (n=671). In the MFI group, adolescents and their parents received lifestyle education using a validated booklet combined with a PA intervention for school students. The EX group received school-based PA only; the CON group continued regular activities. Primary outcomes were PA levels measured with the PAQ-A, and BMI; the secondary outcome was health-related QoL. A linear regression statistical model was used to analyse time, group effects and interactions, with Bonferroni correction for within-group differences at baseline (T0) and at 12-weeks (T1) (post-intervention), 6-month (T2) and 12-month (T3) follow-ups.
UNASSIGNED: Significant time and group effects observed for all groups with PA scores (p<0.001), with MFI group having largest increase in PA; with BMI (p<0.001) and MFI showing the least gain in BMI; and HRQOL (p<0.001), with MFI group showing greatest improvement in scores. There were significant increases in PA at T1 and T3 time-points with the EX group, and at T3 time-point only for MFI and CON, with MFI group showing largest increase in HRQOL scores. BMI increased significantly for all groups at T2 (MFI p=0.001, EX p<0.001) and T3 (p<0.001), while HRQOL increased significantly for both MFI and EX at both follow-ups (p<0.001).
UNASSIGNED: School-based lifestyle MFI was more effective for improving PA, lifestyle behaviours and HRQOL than exercise alone for adolescents, although BMI was not reduced. MFI with PA could be an effective school-based approach for behaviour modification but BMI has limitations for measuring body composition changes.
UNASSIGNED: CTRI/2019/04/018834 (30/04/2019).
摘要：
■确定多因素生活方式干预对身体活动（PA）的影响，肥胖和超重青少年的BMI和健康相关生活质量(QoL)。
■印度的9所学校在一项为期12个月的研究中随机聚集，学生被分配到多因素干预（MFI）。或仅锻炼（EX）或控制（CON）组。参与者为11-16岁的青少年（n=671）。在MFI组中，青少年和他们的父母使用经过验证的小册子接受了生活方式教育，并对在校学生进行了PA干预。EX小组仅接受学校基础的PA；CON小组继续进行常规活动。主要结果是用PAQ-A测量的PA水平，和BMI；次要结局是与健康相关的QoL。线性回归统计模型用于分析时间，群体效应和相互作用，使用Bonferroni校正基线（T0）和12周（T1）（干预后）的组内差异，6个月（T2）和12个月（T3）随访。
■对所有PA评分组观察到的显着时间和组效应（p<0.001），MFI组的PA增加最大；BMI（p<0.001）和MFI显示BMI增加最少；和HRQOL（p<0.001），MFI组得分改善最大。在T1和T3时间点，EX组的PA显著增加，在T3时间点仅适用于MFI和CON，MFI组HRQOL评分增加幅度最大。在T2（MFIp=0.001，EXp<0.001）和T3（p<0.001）时，所有组的BMI均显着增加，而MFI和EX的HRQOL在两次随访中均显著增加(p<0.001)。
■以学校为基础的生活方式MFI对改善PA更有效，青少年的生活方式行为和HRQOL比单独运动，虽然BMI没有降低。带有PA的MFI可能是一种有效的基于学校的行为矫正方法，但BMI在测量身体成分变化方面存在局限性。
■CTRI/2019/04/018834（2019年4月30日）。
■印度的9所学校在一项为期12个月的研究中随机聚集，学生被分配到多因素干预（MFI）。或仅锻炼（EX）或控制（CON）组。参与者为11-16岁的青少年（n=671）。在MFI组中，青少年和他们的父母使用经过验证的小册子接受了生活方式教育，并对在校学生进行了PA干预。EX小组仅接受学校基础的PA；CON小组继续进行常规活动。主要结果是用PAQ-A测量的PA水平，和BMI；次要结局是与健康相关的QoL。线性回归统计模型用于分析时间，群体效应和相互作用，使用Bonferroni校正基线（T0）和12周（T1）（干预后）的组内差异，6个月（T2）和12个月（T3）随访。
■对所有PA评分组观察到的显着时间和组效应（p<0.001），MFI组的PA增加最大；BMI（p<0.001）和MFI显示BMI增加最少；和HRQOL（p<0.001），MFI组得分改善最大。在T1和T3时间点，EX组的PA显著增加，在T3时间点仅适用于MFI和CON，MFI组HRQOL评分增加幅度最大。在T2（MFIp=0.001，EXp<0.001）和T3（p<0.001）时，所有组的BMI均显着增加，而MFI和EX的HRQOL在两次随访中均显著增加(p<0.001)。
■以学校为基础的生活方式MFI对改善PA更有效，青少年的生活方式行为和HRQOL比单独运动，虽然BMI没有降低。带有PA的MFI可能是一种有效的基于学校的行为矫正方法，但BMI在测量身体成分变化方面存在局限性。
■CTRI/2019/04/018834（2019年4月30日）。
